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Search Thermo Fisher Scientific
Immunogen sequence: ERGKHDGSHE GTVYFKCRHP TGGSFIRPNK VNFGTDFLTA IKNRYVLEDG PEEDRKEQIV TIGNKPVETI GFDSIMKQQS QLSKLQEVSL RNCAVSCAGE
Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 71%.
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hypoparathyroidism, growth and mental retardation, and dysmorphism; Tubulin-folding cofactor E; Tubulin-specific chaperone E
Gene Aliases: HRD; KCS; KCS1; pac2; TBCE
UniProt ID: (Human) Q15813
Entrez Gene ID: (Human) 6905
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