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Recommended positive controls: HeLaS3, HepG2, Raji.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The thromboxane A2 receptor (TBXA2R) is a member of the Prostanoid Receptor subfamily. TBXA2R performs an essential role in hemostasis by interacting with thromboxane A2 to induce platelet aggregation. Thromboxane A2 has been implicated in myocardial infarct, stroke, and asthma. Additionally, thromboxane-prostanoid receptors have been implicated in the pathogenesis of cardiovascular diseases. Changes in TBXA2R function have also been linked to a hereditary bleeding disorder.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Prostanoid TP receptor; Thromboxane A2 receptor; TXA2-R
Gene Aliases: BDPLT13; TBXA2R; TXA2-R
UniProt ID: (Human) P21731
Entrez Gene ID: (Human) 6915
Molecular Function:
G-protein coupled receptor
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