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Immunogen sequence: SEGSSQPEEQ LKSPMAESLD GGCSSSSEDQ GERVRQLSGQ STSSDTTYKG GASEKAGSSP AQGAQNEPPR LNASPAAREE ATSPGAKDMP LSSDGNPKVN EKTVGVIVS
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 90%.
This gene encodes a transcription factor that recognizes the platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 promoter. The encoded protein is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Mutations in this gene are associated with autism spectrum disorders. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Nuclear factor SPBP; Protein AR1; SPRE-binding protein; Stromelysin-1 PDGF-responsive element-binding protein; stromelysin-1 platelet-derived growth factor-responsive element binding protein; TCF-20; Transcription factor 20; transcription factor 20 (AR1)
Gene Aliases: AR1; KIAA0292; SPBP; TCF-20; TCF20
UniProt ID: (Human) Q9UGU0
Entrez Gene ID: (Human) 6942
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