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The basic helix-loop-helix transcription factor TCF21/Pod1 (also called capsulin or epicardin) is involved in kidney, lung and spleen organogenesis. It is also essential for normal development of the testes and ovaries. TCF21/Pod1 is involved in the transcriptional repression of steroidogenic factor 1 (Sf1/Nr5a1/Ad4BP), an orphan nuclear receptor that regulates the expression of multiple genes (including Scc) that mediate sexual differentiation.
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Protein Aliases: Capsulin; Epicardin; MyoRa2; TCF-21; Transcription factor 21
Gene Aliases: tcf21; zgc:123313
UniProt ID: (Zebrafish) Q32PV5
Entrez Gene ID: (Zebrafish) 558148
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