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TCP-1 eta Antibody (PA5-27393) in WB
Western Blot using TCP-1 eta Polyclonal Antibody (Product # PA5-27393). Various whole cell extracts (30 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with TCP-1 eta Polyclonal Antibody (Product # PA5-27393) diluted at 1:1,000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Product Details
PA5-27393
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 361 and 530 of Human TCP1 eta
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2544869
Product Specific Information
Recommended positive controls: A431, Jurkat.
Predicted reactivity: Mouse (96%), Rat (97%), Zebrafish (92%), Xenopus laevis (93%), Pig (100%), Rabbit (98%), Chicken (94%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The TCP1 eta gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CCT-eta; Chaperonin containing T-complex polypeptide 1 subunit 7; chaperonin containing t-complex polypeptide 1, eta subunit; HIV-1 Nef interacting protein; HIV-1 Nef-interacting protein; MGC110985; T-complex protein 1 subunit eta; TCP-1-eta
Gene Aliases: CCT7; CCTETA; CCTH; NIP7-1; TCP1ETA
UniProt ID: (Human) Q99832
Entrez Gene ID: (Human) 10574
protein folding
binding of sperm to zona pellucida
positive regulation of telomere maintenance via telomerase
protein stabilization
toxin transport
positive regulation of establishment of protein localization to telomere
positive regulation of protein localization to Cajal body
positive regulation of telomerase RNA localization to Cajal body
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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