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FIGURE: 1 / 2
In direct ELISAs, approximately 15% cross-reactivity with recombinant human (rh) Teneurin-3 is observed, and less than 4% cross-reactivity with rhTeneurin-1 is observed.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Promotes the formation of filopodia and enlarged growth cone in neuronal cells. Induces homophilic cell-cell adhesion. May function as a cellular signal transducer. Isoform 2: Acts as a ligand of the ADGRL1 receptor. Mediates axon guidance and heterophilic cell-cell adhesion. {ECO:0000269 PubMed:21724987}. Ten-2 intracellular domain: Induces gene transcription inhibition. {ECO:0000250}.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Neurestin; neurestin alpha; odd Oz/ten-m homolog 2; odz, odd Oz/ten-m homolog 2; Protein Odd Oz/ten-m homolog 2; Ten-2; Ten-m2; Tenascin-M2; Teneurin transmembrane protein 2; Teneurin-2
Gene Aliases: KIAA1127; Lasso; ODZ2; Odz3; Ten-2; TEN-M2; TENM2; TNM2
UniProt ID: (Human) Q9NT68, (Rat) Q9R1K2
Entrez Gene ID: (Human) 57451, (Rat) 117242, (Mouse) 23964
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