Product References
Rhodocetin-αβ selectively breaks the endothelial barrier of the tumor vasculature in HT1080 fibrosarcoma and A431 epidermoid carcinoma tumor models.
Oncotarget
Niland S,Komljenovic D,Macas J,Bracht T,Bäuerle T,Liebner S,Eble JA
MA1-70078 was used in Immunohistochemistry to suggest that the neuropilin-1-MET signaling axis may be a promising drugable target for anti-tumor therapy, and that rhodocetin-αΒ may serve as a lead structure to develop novel anti-tumor drugs that target such vessels.
Fri Apr 27 00:00:00 EDT 2018
Combined blockade of the IL-13 and IL-33 pathways leads to a greater inhibition of type 2 inflammation over inhibition of either pathway alone.
The Journal of allergy and clinical immunology
Ramirez-Carrozzi V,Sambandam A,Zhou M,Yan D,Kang J,Wu X,Suto E,Baca M,Austin C,Xu M,Lee W,Pappu R
MA170078 was used in flow cytometry to study the effect of IL-13 and IL-33 pathways in dysregulated type 2 inflammation.
Wed Feb 01 00:00:00 EST 2017
A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice.
Haematologica
Cañete A,Carmona R,Ariza L,Sánchez MJ,Rojas A,Muñoz-Chápuli R
MA170078 was used in flow cytometry to utilize a G2-Gata4Cre;R26REYFP mouse line to track the developmental fate of the G2-Gata4 cell lineage
Sat Apr 01 00:00:00 EDT 2017
LCN2 overexpression in bone enhances the hematopoietic compartment via modulation of the bone marrow microenvironment.
Journal of cellular physiology
Costa D,Principi E,Lazzarini E,Descalzi F,Cancedda R,Castagnola P,Tavella S
MA170078 was used in flow cytometry to examine the function of lipocalin-2 in bone tissue
Wed Nov 01 00:00:00 EDT 2017
Single Cell Gene Expression Profiling of Skeletal Muscle-Derived Cells.
Methods in molecular biology (Clifton, N.J.)
Gatto S,Puri PL,Malecova B
MA170078 was used in flow cytometry to develop a procedure for isolating the skeletal muscle interstitial cells, termed Fibro-Adipogenic Progenitors, and their gene expression profiling at the single cell level
Mon Feb 26 00:00:00 EST 2018
Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment.
Nature
Dong L,Yu WM,Zheng H,Loh ML,Bunting ST,Pauly M,Huang G,Zhou M,Broxmeyer HE,Scadden DT,Qu CK
MA170078 was used in flow cytometry to elucidate the contribution of Ptpn11 mutations in the bone marrow microenvironment to leukaemogenesis
Thu Nov 10 00:00:00 EST 2016
Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence.
Nature
Ibiza S,García-Cassani B,Ribeiro H,Carvalho T,Almeida L,Marques R,Misic AM,Bartow-McKenney C,Larson DM,Pavan WJ,Eberl G,Grice EA,Veiga-Fernandes H
MA170078 was used in flow cytometry to explain how glial cells impact ILC3-derived IL-22
Thu Jul 21 00:00:00 EDT 2016
A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency.
Nature genetics
Jabara HH,Boyden SE,Chou J,Ramesh N,Massaad MJ,Benson H,Bainter W,Fraulino D,Rahimov F,Sieff C,Liu ZJ,Alshemmari SH,Al-Ramadi BK,Al-Dhekri H,Arnaout R,Abu-Shukair M,Vatsayan A,Silver E,Ahuja S,Davies EG,Sola-Visner M,Ohsumi TK,Andrews NC,Notarangelo LD,Fleming MD,Al-Herz W,Kunkel LM,Geha RS
MA170078 was used in flow cytometry to elucidate the role of TfR1 in adaptive immunity
Fri Jan 01 00:00:00 EST 2016
Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4.
The Journal of experimental medicine
Uckelmann H,Blaszkiewicz S,Nicolae C,Haas S,Schnell A,Wurzer S,Wagener R,Aszodi A,Essers MA
MA170078 was used in flow cytometry to identify Matrilin-4 (Matn4) as a negative regulator of the hematopoietic stem cell stress response
Mon Sep 19 00:00:00 EDT 2016
General control non-derepressible 2 (GCN2) in T cells controls disease progression of autoimmune neuroinflammation.
Journal of neuroimmunology
Keil M,Sonner JK,Lanz TV,Oezen I,Bunse T,Bittner S,Meyer HV,Meuth SG,Wick W,Platten M
MA170078 was used in flow cytometry to investigate the role of general control non-derepressible 2 in resolving autoimmune neuroinflammation
Mon Aug 15 00:00:00 EDT 2016
GRK6 regulates ROS response and maintains hematopoietic stem cell self-renewal.
Cell death & disease
Le Q,Yao W,Chen Y,Yan B,Liu C,Yuan M,Zhou Y,Ma L
MA170078 was used in flow cytometry to use knockout mice to determine if GRK6 contributes to hematopoiesis
Thu Nov 24 00:00:00 EST 2016
IL-25-responsive, lineage-negative KLRG1(hi) cells are multipotential 'inflammatory' type 2 innate lymphoid cells.
Nature immunology
Huang Y,Guo L,Qiu J,Chen X,Hu-Li J,Siebenlist U,Williamson PR,Urban JF,Paul WE
MA1-70078 was used in Flow Cytometry to characterise the existence of an inflammatory ILC2 population responsive to interleukin 25 that complements IL-33-responsive natural ILC2 cells.
Sun Feb 01 00:00:00 EST 2015
Epigenetic plasticity of Cd8a locus during CD8(+) T-cell development and effector differentiation and reprogramming.
Nature communications
Harland KL,Day EB,Apte SH,Russ BE,Doherty PC,Turner SJ,Kelso A
MA1-70078 was used in flow cytometry to demonstrate the heritable downregulation of CD8 during type 2 polarization of murine CD8 positive effector T cells is associated with CpG methylation of the Cd8a locus
Fri Mar 28 00:00:00 EDT 2014
Thymic alterations in mice deficient for the SNARE protein VAMP8/endobrevin.
Cell and tissue research
Kanwar N,Fayyazi A,Backofen B,Nitsche M,Dressel R,von Mollard GF
MA1-70078 was used in flow cytometry to elucidate the role of VAMP8 in the thymus
Sat Nov 01 00:00:00 EDT 2008