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Immunogen sequence: GYSAVVADF GLAEKIPDVS MGSEKLAVVG SPFWMAPEVL RDEPYNEKAD VFSYGIILCE IIARIQADPD YLPRTEMDPK LRPSFVEIGK TLEEILSRLQ EEEQERDRKL QPTARGLLEK APGVKRLSSL DDKIPHKSPC PRRTIWLSRS QSDIFSRKPP RTVSVLDPYY RPRDGAARTP KVNPFSARQD LMGGKIKFFD LPSKSVISLV FDLDAPGPGT MPLADWQEPL APPIRRWCSL PGSPEFLHQE ACPFVGREES LSDGPPPRLS SLKYRVKEIP PFRASALPAA QAHEAMDCSI LQEENGFGSR PQGTSPCPAG ASEEMEVEER PAGSTPATFS TSGIGLQTQG KQDG (190-542 aa encoded by B C033085)
TESK2 or testis-specific kinase 2 is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. The kinase domain of TESK2 is structurally similar to the kinase domain of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). TESK2 is predominantly expressed in testis and prostate and plays an important role in spermatogenesis. TESK2 phosphorylates cofilin specifically at Ser-3 and induces formation of actin stress fibers and focal adhesions.
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Protein Aliases: Dual specificity testis-specific protein kinase 2; Testicular protein kinase 2
Gene Aliases: TESK2
UniProt ID: (Human) Q96S53, (Rat) Q924U5, (Mouse) Q8VCT9
Entrez Gene ID: (Human) 10420, (Rat) 170908, (Mouse) 230661
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