Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MDRSKRNSIA GFPPRVERLE EFEGGGGGEG NVSQVGRVWP SSYRALISAF SRLTRLDDFT CEKIGSGFFS EVFKVRHRAS GQVMALKMNT LSSNRANMLK EVQLMNRLSH PNILRFMGVC VHQGQLHALT EYINSGNLEQ LLDSNLHLPW TVRVKLAYDI AVGLSYLHFK GIFHRDLTSK NCLIKRDENG YSAVVADFGL AEKIPDVSMG SEKLAVVGSP FWMAPEVLRD EPYNEKADVF SYGIILCEII ARIQADPDYL PRTEMDPKLR PSFVEIGKTL EEILSRLQEE EQERDRKLQP TARGLLEKAP GVKRLSSLDD KIPHKSPCPR RTIWLSRSQS DIFSRKPPRT VSVLDPYYRP RDGAARTPKV NPFSARQDLM GGKIKFFDLP SKSVISLVFD LDAPGPGTMP LADWQEPLAP PIRRWCSLPG SPEFLHQEAC PFVGREESLS DGPPPRLSSL KYRVKEIPPF RASALPAAQA HEAMDCSILQ EENGFGSRPQ GTSPCPAGAS EEMEVEERPA GSTPATFSTS GIGLQTQGKQ DG
TESK2 or testis-specific kinase 2 is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. The kinase domain of TESK2 is structurally similar to the kinase domain of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). TESK2 is predominantly expressed in testis and prostate and plays an important role in spermatogenesis. TESK2 phosphorylates cofilin specifically at Ser-3 and induces formation of actin stress fibers and focal adhesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dual specificity testis-specific protein kinase 2; Testicular protein kinase 2
Gene Aliases: TESK2
UniProt ID: (Human) Q96S53
Entrez Gene ID: (Human) 10420
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