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Invitrogen
TGFBI Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 3
TGFBI Antibody (PA5-27261) in WB
Western Blot was performed using Anti-TGFBI Polyclonal Antibody (Product # PA5-27261) and a 68 kDa band corresponding to Transforming growth factor-beta-induced protein ig-h3 was observed across across the cell lines tested. Whole cell extracts (30 µg lysate) of HeLa (Lane 1), A549 (Lane 2), IMR-32 (Lane 3), Raji (Lane 4), Jurkat (Lane 5) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0321BOX). Resolved proteins were then transferred onto a Nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry Blotting Sys... View More
Product Details
PA5-27261
Product Specifications
Species Reactivity
Chicken,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 354 and 670 of Human TGFBI
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2544737
Product Specific Information
Recommended positive controls: HeLa.
Predicted reactivity: Mouse (85%), Rat (85%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta ig-h3; beta-ig-h3; betaig-h3; Kerato-epithelin; RGD-CAP; RGD-containing collagen-associated protein; transforming growth factor beta-induced 68kDa; transforming growth factor, beta induced, 68 kDa; transforming growth factor, beta-induced, 68kD; transforming growth factor, beta-induced, 68kDa; Transforming growth factor-beta-induced protein ig-h3
Gene Aliases: 68kDa; AI181842; AI747162; Beta-ig; Big-h3; BIGH3; CDB1; CDG2; CDGG1; CSD; CSD1; CSD2; CSD3; EBMD; LCD1; RGD-CAP; TGFBI
UniProt ID: (Human) Q15582, (Mouse) P82198
Entrez Gene ID: (Chicken) 395897, (Human) 7045, (Mouse) 21810, (Rat) 116487
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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