Proteintech

TGM1 Polyclonal Antibody

TGM1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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TGM1 Antibody (12912-3-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using 12912-3-AP (TGM1 antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

TGM1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

12912-3-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 9 publications 9 publications

Immunohistochemistry (IHC)

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:600

Immunocytochemistry (ICC/IF)

View 3 publications 3 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TGM1 Fusion Protein Ag3905 (467-817 aa encoded by BC034699)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody recognizes the endogenous 90 kDa TGM1 proteins.

Immunogen sequence: SGIFCCGPC SVESIKNGLV YMKYDTPFIF AEVNSDKVYW QRQDDGSFKI VYVEEKAIGT LIVTKAISSN MREDITYLYK HPEGSDAERK AVETAAAHGS KPNVYANRGS AEDVAMQVEA QDAVMGQDLM VSVMLINHSS SRRTVKLHLY LSVTFYTGVS GTIFKETKKE VELAPGASDR VTMPVAYKEY RPHLVDQGAM LLNVSGHVKE SGQVLAKQHT FRLRTPDLSL TLLGAAVVGQ ECEVQIVFKN PLPVTLTNVV FRLEGSGLQR PKILNVGDIG GNETVTLRQS FVPVRPGPRQ LIASLDSPQL SQVHGVIQVD VAPAPGDGGF FSDAGGDSHL GETIPMASRG GA (467-817 aa encoded by BC034699)

Target Information

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Burns & trauma

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Inhibiting Hyper-O-GlcNAcylation of c-Myc accelerate diabetic wound healing by alleviating keratinocyte dysfunction.

Burns & trauma

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Wed Apr 27 00:00:00 EDT 2022

Inhibiting Hyper-O-GlcNAcylation of c-Myc accelerate diabetic wound healing by alleviating keratinocyte dysfunction.

Burns & trauma

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Wed Apr 27 00:00:00 EDT 2022

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Specialized Living Wound Dressing Based on the Self-Assembly Approach of Tissue Engineering.

Journal of functional biomaterials

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Filaggrin silencing by shRNA directly impairs the skin barrier function of normal human epidermal keratinocytes and then induces an immune response.

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Bioinformatics

Protein Aliases: Epidermal TGase; K polypeptide; K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase; Protein-glutamine gamma-glutamyltransferase K; protein-glutamine-gamma-glutamyltransferase; TG K; TG(K); TGase 1; TGase K; TGase-1; TGK; transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase); transglutaminase 1 isoform; transglutaminase 1, K polypeptide; Transglutaminase K; transglutaminase type 1; transglutaminase, keratinocyte; Transglutaminase-1

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Gene Aliases: 2310004J08Rik; ARCI1; ICR2; KTG; LI; LI1; TGASE; Tgase1; TGK; TGM1

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UniProt ID: (Human) P22735, (Rat) P23606, (Mouse) Q9JLF6

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Entrez Gene ID: (Human) 7051, (Rat) 60335, (Mouse) 21816

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Function(s)

protein-glutamine gamma-glutamyltransferase activity protein binding metal ion binding transferase activity transferase activity, transferring acyl groups transferase

Process(es)

cellular protein modification process positive regulation of keratinocyte proliferation peptide cross-linking keratinocyte differentiation keratinization cell envelope organization positive regulation of cell cycle organ morphogenesis protein metabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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TGM1 Polyclonal Antibody

TGM1 Antibody (12912-3-AP) in IHC (P)

Product Details

12912-3-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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