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Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells.
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Protein Aliases: Epidermal TGase; K polypeptide; K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase; Protein-glutamine gamma-glutamyltransferase K; protein-glutamine-gamma-glutamyltransferase; TG K; TG(K); TGase 1; TGase K; TGase-1; TGK; transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase); transglutaminase 1 isoform; transglutaminase 1, K polypeptide; Transglutaminase K; transglutaminase type 1; transglutaminase, keratinocyte; Transglutaminase-1
Gene Aliases: 2310004J08Rik; ARCI1; ICR2; KTG; LI; LI1; TGASE; Tgase1; TGK; TGM1
UniProt ID: (Human) P22735, (Rat) P23606, (Mouse) Q9JLF6
Entrez Gene ID: (Human) 7051, (Rat) 60335, (Mouse) 21816
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