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Immunogen sequence: QPWNQQGFGV DQSPSAAWMG GFGAQPPQGQ APPPVIPPPN QAGYGMASYQ T
Antigen sequence identity: Mouse 96%; Rat 96%
The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: aging-associated gene 7 protein; Nucleolysin TIAR; T-cluster binding protein; TIA-1-related nucleolysin; TIA-1-related protein
Gene Aliases: TCBP; TIAL1; TIAR
UniProt ID: (Human) Q01085
Entrez Gene ID: (Human) 7073
Molecular Function:
translation initiation factor
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