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Recommended positive controls: 293T, A431, Jurkat, Raji, mouse brain.
Predicted reactivity: Mouse (83%), Rat (83%), Chimpanzee (99%), Bovine (84%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis. [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: testis tissue sperm-binding protein Li 39a; transketolase-like 2; Transketolase-like protein 2
Gene Aliases: 4933401I19Rik; TKTL2
UniProt ID: (Human) Q9H0I9, (Mouse) Q9D4D4
Entrez Gene ID: (Human) 84076, (Mouse) 74419
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