Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Positive test controls include: Mouse liver. The target is usually found in the following locations: Nucleus.
Immunogen sequence: DPSSPRASPA HSPRENGIDK NRLLKKDASS SPASTASSAS STSLKSKEMS LHEKASTPVL KSSTPTPRSD MPTPGTSATP GLRPGLGKPP AIDPLVNQAA
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Grg-1; Groucho-related protein 1; RP11-203D19.1; TLE 1; transducin-like enhancer of split 4 (homolog of Drosophila E(spl)) - like; Transducin-like enhancer protein 1
Gene Aliases: C230057C06Rik; Estm14; Grg-1; Grg1; Tle1; Tle4l
UniProt ID: (Mouse) Q62440
Entrez Gene ID: (Mouse) 21885
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