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Product Details
H00081793-M01
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
2A11
Immunogen
TLR10 (NP_112218.2, 1 a.a. approximately 811 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.44 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: DAPELPEERE LMTNCSNMSL RKVPADLTPA TTTLDLSYNL LFQLQSSDFH SVSKLRVLIL CHNRIQQLDL KTFEFNKELR YLDLSNNRLK SVTWYLLAGL RYLDLSFNDF DTMPICEEAG NMSHLEILGL SGAKIQKSDF QKIAHLHLNT VFLGFRTLPH YEEGSLPILN TTKLHIVLPM DTNFWVLLRD GIKTSKILEM TNIDGKSQFV SYEMQRNLSL ENAKTSVLLL NKVDLLWDDL FLILQFVWHT SVEHF
Target Information
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Its exact function is not known. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD290; MGC104967; MGC126398; MGC126399; Toll-like receptor 10
Gene Aliases: CD290; TLR10; UNQ315/PRO358
UniProt ID: (Human) A8K7L1
Entrez Gene ID: (Human) 81793, (Rat) 305355
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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