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TLR11 Antibody (PA1-41080) in WB
Western blot analysis of TLR11 in mouse testis lysate in the A) the absence and B) presence of blocking peptide and rat testis lysate in C) the absence and D) presence of blocking peptide. Samples were incubated in TLR11 polyclonal antibody (Product # PA1-41080) using a dilution of 3 µg/mL.
Product Details
PA1-41080
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues 911-926 (CEQLKRRLSKAGQERD) of mouse TLR11
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2204418
Target Information
The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). TLR11 does not respond to known TLR ligands but instead respond specifically to uropathogenic bacteria. TLR11-deficient mice are highly susceptible to infection of the kidneys by uropathogenic bacteria, indicating that TLR11 may play a protective role in preventing infection of internal organs of the urogenital system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Gm1365; RP23-392K10.4; Toll-like receptor 11; Toll-like receptor 12
Gene Aliases: Gm287; RGD1564460; Tlr11; Tlr12
UniProt ID: (Mouse) Q6R5P0
Entrez Gene ID: (Mouse) 239081, (Rat) 498491
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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