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Product Details
MA1-41484
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Mouse
/ IgM
Class
Monoclonal
Type
Antibody
Clone
15F1215
Immunogen
Amino acids 791-821 of mouse TLR12
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites/PBS with 0.2% gelatin
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_1087884
Product Specific Information
Based on sequence homology, this antibody may also detect mouse TLR11.
Target Information
The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). TLR12 has been cloned that displays a distinct pattern of expression in macrophages and liver, kidney, and bladder epithelial cells. TLR12 does not respond to known TLR ligands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Gm287; MGC129352; MGC129353; Toll-like receptor 11; Toll-like receptor 12
Gene Aliases: Gm1365; Tlr11; Tlr12
UniProt ID: (Mouse) Q6QNU9
Entrez Gene ID: (Mouse) 384059
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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