Product References
Activation of cDCs and iNKT cells contributes to triptolide-induced hepatotoxicity via STING signaling pathway and endoplasmic reticulum stress.
Cell biology and toxicology
Chen X,Yu Z,Nong C,Xue R,Zhang M,Zhang Y,Sun L,Zhang L,Wang X
Tue Aug 01 00:00:00 EDT 2023
Activation of cDCs and iNKT cells contributes to triptolide-induced hepatotoxicity via STING signaling pathway and endoplasmic reticulum stress.
Cell biology and toxicology
Chen X,Yu Z,Nong C,Xue R,Zhang M,Zhang Y,Sun L,Zhang L,Wang X
Tue Aug 01 00:00:00 EDT 2023
NETs Promote Inflammatory Injury by Activating cGAS-STING Pathway in Acute Lung Injury.
International journal of molecular sciences
Zhao J,Zhen N,Zhou Q,Lou J,Cui W,Zhang G,Tian B
Tue Mar 07 00:00:00 EST 2023
STING activation in platelets aggravates septic thrombosis by enhancing platelet activation and granule secretion.
Immunity
Yang M,Jiang H,Ding C,Zhang L,Ding N,Li G,Zhang F,Wang J,Deng L,Liu J,Xu Y
Tue May 09 00:00:00 EDT 2023
Sirt1 Negatively Regulates Cellular Antiviral Responses by Preventing the Cytoplasmic Translocation of Interferon-Inducible Protein 16 in Human Cells.
Journal of virology
Wang J,Qin X,Huang Y,Zhang G,Liu Y,Cui Y,Wang Y,Pei J,Ma S,Song Z,Zhu X,Wang H,Yang B
Tue Feb 28 00:00:00 EST 2023
cGAS-STING pathway aggravates early cerebral ischemia-reperfusion injury in mice by activating NCOA4-mediated ferritinophagy.
Experimental neurology
Li B,Wang W,Li Y,Wang S,Liu H,Xia Z,Gao W,Zhao B
Sun Jan 01 00:00:00 EST 2023
Chemoproteomics reveals microbiota-derived aromatic monoamine agonists for GPRC5A.
Nature chemical biology
Zhao X,Stein KR,Chen V,Griffin ME,Lairson LL,Hang HC
Sun Oct 01 00:00:00 EDT 2023
DNA virus oncoprotein HPV18 E7 selectively antagonizes cGAS-STING-triggered innate immune activation.
Journal of medical virology
Lou M,Huang D,Zhou Z,Shi X,Wu M,Rui Y,Su J,Zheng W,Yu XF
Sun Jan 01 00:00:00 EST 2023
TAK1 deficiency promotes liver injury and tumorigenesis via ferroptosis and macrophage cGAS-STING signalling.
JHEP reports : innovation in hepatology
Su W,Gao W,Zhang R,Wang Q,Li L,Bu Q,Xu Z,Liu Z,Wang M,Zhu Y,Wu G,Zhou H,Wang X,Lu L
Mon May 01 00:00:00 EDT 2023
TAK1 deficiency promotes liver injury and tumorigenesis via ferroptosis and macrophage cGAS-STING signalling.
JHEP reports : innovation in hepatology
Su W,Gao W,Zhang R,Wang Q,Li L,Bu Q,Xu Z,Liu Z,Wang M,Zhu Y,Wu G,Zhou H,Wang X,Lu L
Mon May 01 00:00:00 EDT 2023
Schisandrin C enhances cGAS-STING pathway activation and inhibits HBV replication.
Journal of ethnopharmacology
Zhao J,Xu G,Hou X,Mu W,Yang H,Shi W,Wen J,Liu T,Wu Z,Bai J,Zhang P,Wang Z,Xiao X,Zou W,Bai Z,Zhan X
Sat Jul 15 00:00:00 EDT 2023
C9ORF72 suppresses JAK-STAT mediated inflammation.
iScience
Pang W,Hu F
Fri May 19 00:00:00 EDT 2023
C9ORF72 suppresses JAK-STAT mediated inflammation.
iScience
Pang W,Hu F
Fri May 19 00:00:00 EDT 2023
SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool.
Nature cell biology
Ji Y,Luo Y,Wu Y,Sun Y,Zhao L,Xue Z,Sun M,Wei X,He Z,Wu SA,Lin LL,Lu Y,Chang L,Chen F,Chen S,Qian W,Xu X,Chen S,Pan D,Zhou Z,Xia S,Hu CA,Liang T,Qi L
Mon May 01 00:00:00 EDT 2023
SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool.
Nature cell biology
Ji Y,Luo Y,Wu Y,Sun Y,Zhao L,Xue Z,Sun M,Wei X,He Z,Wu SA,Lin LL,Lu Y,Chang L,Chen F,Chen S,Qian W,Xu X,Chen S,Pan D,Zhou Z,Xia S,Hu CA,Liang T,Qi L
Mon May 01 00:00:00 EDT 2023
SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool.
Nature cell biology
Ji Y,Luo Y,Wu Y,Sun Y,Zhao L,Xue Z,Sun M,Wei X,He Z,Wu SA,Lin LL,Lu Y,Chang L,Chen F,Chen S,Qian W,Xu X,Chen S,Pan D,Zhou Z,Xia S,Hu CA,Liang T,Qi L
Mon May 01 00:00:00 EDT 2023
Human kidney organoids model of Esculentoside A nephrotoxicity to investigate the role of epithelial-mesenchymal transition via STING signaling.
Toxicology letters
Gu S,Wu G,Lu D,Wang Y,Tang L,Zhang W
Sun Jan 15 00:00:00 EST 2023
Protocol for the identification and expression analysis of a cytoplasmic membrane-localized protein STING.
STAR protocols
Shi J,Liu C,Luo S,Zhang Y,Li M,Zhou M,Weng M,Li X,Zheng T
Mon Mar 20 00:00:00 EDT 2023
Silk fibroin peptide self-assembled nanofibers delivered naringenin to alleviate cisplatin-induced acute kidney injury by inhibiting mtDNA-cGAS-STING pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Liu S,Gao X,Yin Y,Wang J,Dong K,Shi D,Wu X,Guo C
Sat Jul 01 00:00:00 EDT 2023
Silk fibroin peptide self-assembled nanofibers delivered naringenin to alleviate cisplatin-induced acute kidney injury by inhibiting mtDNA-cGAS-STING pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Liu S,Gao X,Yin Y,Wang J,Dong K,Shi D,Wu X,Guo C
Sat Jul 01 00:00:00 EDT 2023
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
Cell death & disease
Li J,Sun Y,Zhao X,Ma Y,Xie Y,Liu S,Hui B,Shi X,Sun X,Zhang X
Sat Apr 08 00:00:00 EDT 2023
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
Cell death & disease
Li J,Sun Y,Zhao X,Ma Y,Xie Y,Liu S,Hui B,Shi X,Sun X,Zhang X
Sat Apr 08 00:00:00 EDT 2023
The role of chemerin in the regulation of cGAS-STING pathway in gestational diabetes mellitus placenta.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhou X,Zhang H,Jiang Y,Wei L,Chen Y,Zhang J,Gao P,Zhu S,Fang C,Du Y,Su R,He M,Yu J,Wang S,Ding W,Feng L
Wed Mar 01 00:00:00 EST 2023
The role of chemerin in the regulation of cGAS-STING pathway in gestational diabetes mellitus placenta.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhou X,Zhang H,Jiang Y,Wei L,Chen Y,Zhang J,Gao P,Zhu S,Fang C,Du Y,Su R,He M,Yu J,Wang S,Ding W,Feng L
Wed Mar 01 00:00:00 EST 2023
STING deficiency protects against wasp venom-induced acute kidney injury.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Lv Y,Lu L,Yu F,Gao Z,Yuan H,Hu F
Sat Jul 01 00:00:00 EDT 2023
TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion.
Signal transduction and targeted therapy
Zheng W,Zhou Z,Rui Y,Ye R,Xia F,Guo F,Liu X,Su J,Lou M,Yu XF
Fri Feb 24 00:00:00 EST 2023
TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion.
Signal transduction and targeted therapy
Zheng W,Zhou Z,Rui Y,Ye R,Xia F,Guo F,Liu X,Su J,Lou M,Yu XF
Fri Feb 24 00:00:00 EST 2023
Naringin protects against inflammation and apoptosis induced by intestinal ischemia-reperfusion injury through deactivation of cGAS-STING signaling pathway.
Phytotherapy research : PTR
Gu L,Wang F,Wang Y,Sun D,Sun Y,Tian T,Meng Q,Yin L,Xu L,Lu X,Peng J,Lin Y,Sun P
Tue Aug 01 00:00:00 EDT 2023
The mechanism of STING autoinhibition and activation.
Molecular cell
Liu S,Yang B,Hou Y,Cui K,Yang X,Li X,Chen L,Liu S,Zhang Z,Jia Y,Xie Y,Xue Y,Li X,Yan B,Wu C,Deng W,Qi J,Lu D,Gao GF,Wang P,Shang G
Thu May 04 00:00:00 EDT 2023
NF-κB regulates the expression of STING via alternative promoter usage.
Life sciences
Chen LY,Pang XY,Chen C,Xu HG
Wed Feb 01 00:00:00 EST 2023
Zhen Wu decoction represses renal fibrosis by invigorating tubular NRF2 and TFAM to fuel mitochondrial bioenergetics.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zheng M,Hu Z,Wang Y,Wang C,Zhong C,Cui W,You J,Gao B,Sun X,La L
Sun Jan 01 00:00:00 EST 2023
Zhen Wu decoction represses renal fibrosis by invigorating tubular NRF2 and TFAM to fuel mitochondrial bioenergetics.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zheng M,Hu Z,Wang Y,Wang C,Zhong C,Cui W,You J,Gao B,Sun X,La L
Sun Jan 01 00:00:00 EST 2023
Zhen Wu decoction represses renal fibrosis by invigorating tubular NRF2 and TFAM to fuel mitochondrial bioenergetics.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zheng M,Hu Z,Wang Y,Wang C,Zhong C,Cui W,You J,Gao B,Sun X,La L
Sun Jan 01 00:00:00 EST 2023
Zhen Wu decoction represses renal fibrosis by invigorating tubular NRF2 and TFAM to fuel mitochondrial bioenergetics.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zheng M,Hu Z,Wang Y,Wang C,Zhong C,Cui W,You J,Gao B,Sun X,La L
Sun Jan 01 00:00:00 EST 2023
Myricetin-Loaded Nanomicelles Protect against Cisplatin-Induced Acute Kidney Injury by Inhibiting the DNA Damage-cGAS-STING Signaling Pathway.
Molecular pharmaceutics
Qi X,Wang J,Fei F,Gao X,Wu X,Shi D,Guo C
Mon Jan 02 00:00:00 EST 2023
Inhibition of cGAS aggravated the host inflammatory response to Aspergillus fumigatus.
Experimental lung research
Peng M,Li X,Zhang X,Peng L
Sat Dec 16 00:00:00 EST 2023
Tegument protein UL21 of alpha-herpesvirus inhibits the innate immunity by triggering CGAS degradation through TOLLIP-mediated selective autophagy.
Autophagy
Ma Z,Bai J,Jiang C,Zhu H,Liu D,Pan M,Wang X,Pi J,Jiang P,Liu X
Mon May 01 00:00:00 EDT 2023
Protocol using lentivirus to establish THP-1 suspension cell lines for immunostaining and confocal microscopy.
STAR protocols
Ji W,Zhang L,Liu X
Fri Mar 17 00:00:00 EDT 2023
Borrelia burgdorferi Engages Mammalian Type I IFN Responses via the cGAS-STING Pathway.
Journal of immunology (Baltimore, Md. : 1950)
Farris LC,Torres-Odio S,Adams LG,West AP,Hyde JA
Thu Jun 01 00:00:00 EDT 2023
ARMH3-mediated recruitment of PI4KB directs Golgi-to-endosome trafficking and activation of the antiviral effector STING.
Immunity
Fang R,Jiang Q,Jia X,Jiang Z
Tue Mar 14 00:00:00 EDT 2023
ARMH3-mediated recruitment of PI4KB directs Golgi-to-endosome trafficking and activation of the antiviral effector STING.
Immunity
Fang R,Jiang Q,Jia X,Jiang Z
Tue Mar 14 00:00:00 EDT 2023
Moderate Intensity of Treadmill Exercise Rescues TBI-Induced Ferroptosis, Neurodegeneration, and Cognitive Impairments via Suppressing STING Pathway.
Molecular neurobiology
Chen J,Zhu T,Yu D,Yan B,Zhang Y,Jin J,Yang Z,Zhang B,Hao X,Chen Z,Yan C,Yu J
Fri Sep 01 00:00:00 EDT 2023
Moderate Intensity of Treadmill Exercise Rescues TBI-Induced Ferroptosis, Neurodegeneration, and Cognitive Impairments via Suppressing STING Pathway.
Molecular neurobiology
Chen J,Zhu T,Yu D,Yan B,Zhang Y,Jin J,Yang Z,Zhang B,Hao X,Chen Z,Yan C,Yu J
Fri Sep 01 00:00:00 EDT 2023
Aβ Induces Neuroinflammation and Microglial M1 Polarization via cGAS-STING-IFITM3 Signaling Pathway in BV-2 Cells.
Neurochemical research
Wu Z,Tang W,Ibrahim FEEM,Chen X,Yan H,Tao C,Wang Z,Guo Y,Fu Y,Wang Q,Ge Y
Fri Sep 01 00:00:00 EDT 2023
Inhibition of cGAS ameliorates acute lung injury triggered by zinc oxide nanoparticles.
Toxicology letters
Jiang Z,Jiang Y,Fan J,Zhang J,Xu G,Fan Y,Zhang L,Qin X,Jiang X,Mao L,Liu G,Chen C,Zou Z
Sun Jan 15 00:00:00 EST 2023
Inhibition of cGAS ameliorates acute lung injury triggered by zinc oxide nanoparticles.
Toxicology letters
Jiang Z,Jiang Y,Fan J,Zhang J,Xu G,Fan Y,Zhang L,Qin X,Jiang X,Mao L,Liu G,Chen C,Zou Z
Sun Jan 15 00:00:00 EST 2023
Inhibition of cGAS ameliorates acute lung injury triggered by zinc oxide nanoparticles.
Toxicology letters
Jiang Z,Jiang Y,Fan J,Zhang J,Xu G,Fan Y,Zhang L,Qin X,Jiang X,Mao L,Liu G,Chen C,Zou Z
Sun Jan 15 00:00:00 EST 2023
Inhibition of cGAS ameliorates acute lung injury triggered by zinc oxide nanoparticles.
Toxicology letters
Jiang Z,Jiang Y,Fan J,Zhang J,Xu G,Fan Y,Zhang L,Qin X,Jiang X,Mao L,Liu G,Chen C,Zou Z
Sun Jan 15 00:00:00 EST 2023
Proteomic analysis predicts anti-angiogenic resistance in recurred glioblastoma.
Journal of translational medicine
Jeon H,Byun J,Kang H,Kim K,Lee E,Kim JH,Hong CK,Song SW,Kim YH,Chong S,Kim JH,Nam SJ,Park JE,Lee S
Thu Feb 02 00:00:00 EST 2023
A role of STING signaling in obesity-induced lung inflammation.
International journal of obesity (2005)
Qi Y,Wu Z,Chen D,Zhu L,Yang Y
Sat Apr 01 00:00:00 EDT 2023
Manganese Mediates Its Antiviral Functions in a cGAS-STING Pathway Independent Manner.
Viruses
Sun S,Xu Y,Qiu M,Jiang S,Cao Q,Luo J,Zhang T,Chen N,Zheng W,Meurens F,Liu Z,Zhu J
Tue Feb 28 00:00:00 EST 2023
Effect of STING signaling on intestinal barrier damage in severe acute pancreatitis.
Experimental cell research
Zhang Y,Jiang Y,Li H,Wang J,Li C,Zhang D
Sat Jul 15 00:00:00 EDT 2023
STING contributes to trauma-induced heterotopic ossification through NLRP3-dependent macrophage pyroptosis.
Clinical immunology (Orlando, Fla.)
Sun Z,Liu H,Hu Y,Luo G,Yuan Z,Tu B,Ruan H,Li J,Fan C
Mon May 01 00:00:00 EDT 2023
STING contributes to trauma-induced heterotopic ossification through NLRP3-dependent macrophage pyroptosis.
Clinical immunology (Orlando, Fla.)
Sun Z,Liu H,Hu Y,Luo G,Yuan Z,Tu B,Ruan H,Li J,Fan C
Mon May 01 00:00:00 EDT 2023
Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis.
Cell reports
Ji W,Zhang L,Ma C,Xu X,Li S,Xia H,Zhou W,Liu X
Tue Apr 25 00:00:00 EDT 2023
STING mediates experimental osteoarthritis and mechanical allodynia in mouse.
Arthritis research & therapy
Shin Y,Cho D,Kim SK,Chun JS
Wed May 31 00:00:00 EDT 2023
STING mediates experimental osteoarthritis and mechanical allodynia in mouse.
Arthritis research & therapy
Shin Y,Cho D,Kim SK,Chun JS
Wed May 31 00:00:00 EDT 2023
STING mediates experimental osteoarthritis and mechanical allodynia in mouse.
Arthritis research & therapy
Shin Y,Cho D,Kim SK,Chun JS
Wed May 31 00:00:00 EDT 2023
STING mediates experimental osteoarthritis and mechanical allodynia in mouse.
Arthritis research & therapy
Shin Y,Cho D,Kim SK,Chun JS
Wed May 31 00:00:00 EDT 2023
Novel STING-targeted PET radiotracer for alert and therapeutic evaluation of acute lung injury.
Acta pharmaceutica Sinica. B
Xu D,Yang F,Chen J,Zhu T,Wang F,Xiao Y,Liang Z,Bi L,Huang G,Jiang Z,Shan H,Li D
Mon May 01 00:00:00 EDT 2023
Novel STING-targeted PET radiotracer for alert and therapeutic evaluation of acute lung injury.
Acta pharmaceutica Sinica. B
Xu D,Yang F,Chen J,Zhu T,Wang F,Xiao Y,Liang Z,Bi L,Huang G,Jiang Z,Shan H,Li D
Mon May 01 00:00:00 EDT 2023
Novel STING-targeted PET radiotracer for alert and therapeutic evaluation of acute lung injury.
Acta pharmaceutica Sinica. B
Xu D,Yang F,Chen J,Zhu T,Wang F,Xiao Y,Liang Z,Bi L,Huang G,Jiang Z,Shan H,Li D
Mon May 01 00:00:00 EDT 2023
Novel STING-targeted PET radiotracer for alert and therapeutic evaluation of acute lung injury.
Acta pharmaceutica Sinica. B
Xu D,Yang F,Chen J,Zhu T,Wang F,Xiao Y,Liang Z,Bi L,Huang G,Jiang Z,Shan H,Li D
Mon May 01 00:00:00 EDT 2023
Novel STING-targeted PET radiotracer for alert and therapeutic evaluation of acute lung injury.
Acta pharmaceutica Sinica. B
Xu D,Yang F,Chen J,Zhu T,Wang F,Xiao Y,Liang Z,Bi L,Huang G,Jiang Z,Shan H,Li D
Mon May 01 00:00:00 EDT 2023
Novel STING-targeted PET radiotracer for alert and therapeutic evaluation of acute lung injury.
Acta pharmaceutica Sinica. B
Xu D,Yang F,Chen J,Zhu T,Wang F,Xiao Y,Liang Z,Bi L,Huang G,Jiang Z,Shan H,Li D
Mon May 01 00:00:00 EDT 2023
Flavonoid derivative DMXAA attenuates cisplatin-induced acute kidney injury independent of STING signaling.
Clinical science (London, England : 1979)
Lu L,Liu W,Li S,Bai M,Zhou Y,Jiang Z,Jia Z,Huang S,Zhang A,Gong W
Fri Mar 31 00:00:00 EDT 2023
African Swine Fever Virus L83L Negatively Regulates the cGAS-STING-Mediated IFN-I Pathway by Recruiting Tollip To Promote STING Autophagic Degradation.
Journal of virology
Cheng M,Kanyema MM,Sun Y,Zhao W,Lu Y,Wang J,Li X,Shi C,Wang J,Wang N,Yang W,Jiang Y,Huang H,Yang G,Zeng Y,Wang C,Cao X
Tue Feb 28 00:00:00 EST 2023
African Swine Fever Virus L83L Negatively Regulates the cGAS-STING-Mediated IFN-I Pathway by Recruiting Tollip To Promote STING Autophagic Degradation.
Journal of virology
Cheng M,Kanyema MM,Sun Y,Zhao W,Lu Y,Wang J,Li X,Shi C,Wang J,Wang N,Yang W,Jiang Y,Huang H,Yang G,Zeng Y,Wang C,Cao X
Tue Feb 28 00:00:00 EST 2023
African Swine Fever Virus L83L Negatively Regulates the cGAS-STING-Mediated IFN-I Pathway by Recruiting Tollip To Promote STING Autophagic Degradation.
Journal of virology
Cheng M,Kanyema MM,Sun Y,Zhao W,Lu Y,Wang J,Li X,Shi C,Wang J,Wang N,Yang W,Jiang Y,Huang H,Yang G,Zeng Y,Wang C,Cao X
Tue Feb 28 00:00:00 EST 2023
Yi-Shen-Xie-Zhuo formula alleviates cisplatin-induced AKI by regulating inflammation and apoptosis via the cGAS/STING pathway.
Journal of ethnopharmacology
Qi J,Luo Q,Zhang Q,Wu M,Zhang L,Qin L,Xue Q,Nie X
Mon Jun 12 00:00:00 EDT 2023
The cGAS-STING pathway promotes endometriosis by up-regulating autophagy.
International immunopharmacology
Zhu S,Chen Q,Sun J,Du W,Chen Z,Yu M,Tao J,Zhou Y,Zhao Y,Zhang Q
Sat Apr 01 00:00:00 EDT 2023
The cGAS-STING pathway promotes endometriosis by up-regulating autophagy.
International immunopharmacology
Zhu S,Chen Q,Sun J,Du W,Chen Z,Yu M,Tao J,Zhou Y,Zhao Y,Zhang Q
Sat Apr 01 00:00:00 EDT 2023
The cGAS-STING pathway promotes endometriosis by up-regulating autophagy.
International immunopharmacology
Zhu S,Chen Q,Sun J,Du W,Chen Z,Yu M,Tao J,Zhou Y,Zhao Y,Zhang Q
Sat Apr 01 00:00:00 EDT 2023
The cGAS-STING pathway promotes endometriosis by up-regulating autophagy.
International immunopharmacology
Zhu S,Chen Q,Sun J,Du W,Chen Z,Yu M,Tao J,Zhou Y,Zhao Y,Zhang Q
Sat Apr 01 00:00:00 EDT 2023
Yes-Associated Protein 1 Inhibition Induces Immunogenic Cell Death and Synergizes With Radiation and PD-1 Blockade.
International journal of radiation oncology, biology, physics
Zhuang Y,Wang Y,Liu C,Li S,Du S,Li G
Sat Jul 15 00:00:00 EDT 2023
Induction of Inflammation Disrupts the Negative Interplay between STING and S1P Axis That Is Observed during Physiological Conditions in the Lung.
International journal of molecular sciences
Terlizzi M,Colarusso C,Falanga A,Somma P,De Rosa I,Panico L,Pinto A,Maiolino P,Sorrentino R
Fri May 05 00:00:00 EDT 2023
Murine Coronavirus Disease 2019 Lethality Is Characterized by Lymphoid Depletion Associated with Suppressed Antigen-Presenting Cell Functionality.
The American journal of pathology
Lee YJ,Seok SH,Lee NY,Choi HJ,Lee YW,Chang HJ,Hwang JY,On DI,Noh HA,Lee SB,Kwon HK,Yun JW,Shin JS,Seo JY,Nam KT,Lee H,Lee HY,Park JW,Seong JK
Sat Jul 01 00:00:00 EDT 2023
Activation of the STING pathway induces peripheral sensitization via neuroinflammation in a rat model of bone cancer pain.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Zhang Y,Wang W,Gong Z,Peng Y,Li X,Zhang Z,Zhang X,You X,Wu J
Sun Jan 01 00:00:00 EST 2023
The Papain-Like Protease of Porcine Reproductive and Respiratory Syndrome Virus Impedes STING Translocation from the Endoplasmic Reticulum to the Golgi Apparatus by Deubiquitinating STIM1.
Journal of virology
Diao F,Bai J,Jiang C,Sun Y,Gao Y,Nauwynck H,Jiang P,Liu X
Thu Apr 27 00:00:00 EDT 2023
The Papain-Like Protease of Porcine Reproductive and Respiratory Syndrome Virus Impedes STING Translocation from the Endoplasmic Reticulum to the Golgi Apparatus by Deubiquitinating STIM1.
Journal of virology
Diao F,Bai J,Jiang C,Sun Y,Gao Y,Nauwynck H,Jiang P,Liu X
Thu Apr 27 00:00:00 EDT 2023
The Papain-Like Protease of Porcine Reproductive and Respiratory Syndrome Virus Impedes STING Translocation from the Endoplasmic Reticulum to the Golgi Apparatus by Deubiquitinating STIM1.
Journal of virology
Diao F,Bai J,Jiang C,Sun Y,Gao Y,Nauwynck H,Jiang P,Liu X
Thu Apr 27 00:00:00 EDT 2023
4-octyl itaconate as a metabolite derivative inhibits inflammation via alkylation of STING.
Cell reports
Li W,Li Y,Kang J,Jiang H,Gong W,Chen L,Wu C,Liu M,Wu X,Zhao Y,Ren J
Tue Mar 28 00:00:00 EDT 2023
Flavonoids derived from licorice suppress LPS-induced acute lung injury in mice by inhibiting the cGAS-STING signaling pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Wen J,Qin S,Li Y,Zhang P,Zhan X,Fang M,Shi C,Mu W,Kan W,Zhao J,Hui S,Hou M,Li H,Xiao X,Xu G,Bai Z
Mon May 01 00:00:00 EDT 2023
ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer.
Developmental cell
Yi J,Wang L,Du J,Wang M,Shen H,Liu Z,Qin Y,Liu J,Hu G,Xiao R,Ding J,Chen X,Wang H,Huang H,Ouyang G,Liu W
Mon May 08 00:00:00 EDT 2023
Rhinovirus C replication is associated with the endoplasmic reticulum and triggers cytopathic effects in an in vitro model of human airway epithelium.
PLoS pathogens
Gagliardi TB,Goldstein ME,Song D,Gray KM,Jung JW,Ignacio MA,Stroka KM,Duncan GA,Scull MA
Sat Jan 01 00:00:00 EST 2022
New mechanism of nephrotoxicity of triptolide: Oxidative stress promotes cGAS-STING signaling pathway.
Free radical biology & medicine
Lu J,Zhang Y,Dong H,Sun J,Zhu L,Liu P,Wen F,Lin R
Mon Aug 01 00:00:00 EDT 2022
New mechanism of nephrotoxicity of triptolide: Oxidative stress promotes cGAS-STING signaling pathway.
Free radical biology & medicine
Lu J,Zhang Y,Dong H,Sun J,Zhu L,Liu P,Wen F,Lin R
Mon Aug 01 00:00:00 EDT 2022
New mechanism of nephrotoxicity of triptolide: Oxidative stress promotes cGAS-STING signaling pathway.
Free radical biology & medicine
Lu J,Zhang Y,Dong H,Sun J,Zhu L,Liu P,Wen F,Lin R
Mon Aug 01 00:00:00 EDT 2022
New mechanism of nephrotoxicity of triptolide: Oxidative stress promotes cGAS-STING signaling pathway.
Free radical biology & medicine
Lu J,Zhang Y,Dong H,Sun J,Zhu L,Liu P,Wen F,Lin R
Mon Aug 01 00:00:00 EDT 2022
BAP1 maintains HIF-dependent interferon beta induction to suppress tumor growth in clear cell renal cell carcinoma.
Cancer letters
Langbein LE,El Hajjar R,He S,Sementino E,Zhong Z,Jiang W,Leiby BE,Li L,Uzzo RG,Testa JR,Yang H
Fri Oct 28 00:00:00 EDT 2022
Circulating cell-free mtDNA release is associated with the activation of cGAS-STING pathway and inflammation in mitochondrial diseases.
Journal of neurology
Zhao X,Yu M,Zhao Y,Zheng Y,Meng L,Du K,Xie Z,Lv H,Zhang W,Liu J,Wang Q,Yuan Y,Wang Z,Deng J
Thu Sep 01 00:00:00 EDT 2022
Predicting the Immune Microenvironment and Prognosis with a NETosis-Related lncRNA Signature in Head and Neck Squamous Cell Carcinoma.
BioMed research international
He X,Xiao Y,Liu S,Deng R,Li Z,Zhu X
Mon Sep 26 00:00:00 EDT 2022
Activation of cGAS-STING pathway - A possible cause of myofiber atrophy/necrosis in dermatomyositis and immune-mediated necrotizing myopathy.
Journal of clinical laboratory analysis
Zhou M,Cheng X,Zhu W,Jiang J,Zhu S,Wu X,Liu M,Fang Q
Sat Oct 01 00:00:00 EDT 2022
An alternatively spliced STING isoform localizes in the cytoplasmic membrane and directly senses extracellular cGAMP.
The Journal of clinical investigation
Li X,Zhu Y,Zhang X,An X,Weng M,Shi J,Wang S,Liu C,Luo S,Zheng T
Tue Feb 01 00:00:00 EST 2022
An alternatively spliced STING isoform localizes in the cytoplasmic membrane and directly senses extracellular cGAMP.
The Journal of clinical investigation
Li X,Zhu Y,Zhang X,An X,Weng M,Shi J,Wang S,Liu C,Luo S,Zheng T
Tue Feb 01 00:00:00 EST 2022
An alternatively spliced STING isoform localizes in the cytoplasmic membrane and directly senses extracellular cGAMP.
The Journal of clinical investigation
Li X,Zhu Y,Zhang X,An X,Weng M,Shi J,Wang S,Liu C,Luo S,Zheng T
Tue Feb 01 00:00:00 EST 2022
An alternatively spliced STING isoform localizes in the cytoplasmic membrane and directly senses extracellular cGAMP.
The Journal of clinical investigation
Li X,Zhu Y,Zhang X,An X,Weng M,Shi J,Wang S,Liu C,Luo S,Zheng T
Tue Feb 01 00:00:00 EST 2022
An alternatively spliced STING isoform localizes in the cytoplasmic membrane and directly senses extracellular cGAMP.
The Journal of clinical investigation
Li X,Zhu Y,Zhang X,An X,Weng M,Shi J,Wang S,Liu C,Luo S,Zheng T
Tue Feb 01 00:00:00 EST 2022
An alternatively spliced STING isoform localizes in the cytoplasmic membrane and directly senses extracellular cGAMP.
The Journal of clinical investigation
Li X,Zhu Y,Zhang X,An X,Weng M,Shi J,Wang S,Liu C,Luo S,Zheng T
Tue Feb 01 00:00:00 EST 2022
Chlorin e6-Induced Photodynamic Effect Polarizes the Macrophage Into an M1 Phenotype Through Oxidative DNA Damage and Activation of STING.
Frontiers in pharmacology
Yu TT,Han N,Li LG,Peng XC,Li QR,Xu HZ,Wang XY,Yang ZY,Chen X,Wang MF,Li TF
Tue Mar 22 00:00:00 EDT 2022
Chlorin e6-Induced Photodynamic Effect Polarizes the Macrophage Into an M1 Phenotype Through Oxidative DNA Damage and Activation of STING.
Frontiers in pharmacology
Yu TT,Han N,Li LG,Peng XC,Li QR,Xu HZ,Wang XY,Yang ZY,Chen X,Wang MF,Li TF
Tue Mar 22 00:00:00 EDT 2022
Sustained IL-4 priming of macrophages enhances the inflammatory response to TLR7/8 ligand R848.
Journal of leukocyte biology
Banete A,Gee K,Basta S
Tue Feb 01 00:00:00 EST 2022
The Porcine Cyclic GMP-AMP Synthase-STING Pathway Exerts an Unusual Antiviral Function Independent of Interferon and Autophagy.
Journal of virology
Jiang S,Xia N,Luo J,Zhang Y,Cao Q,Zhang J,Wang Y,Zhao Y,Zheng W,Chen N,Meurens F,Li X,Zhu J
Wed Dec 14 00:00:00 EST 2022
Lipotoxicity-induced STING1 activation stimulates MTORC1 and restricts hepatic lipophagy.
Autophagy
Liu K,Qiu D,Liang X,Huang Y,Wang Y,Jia X,Li K,Zhao J,Du C,Qiu X,Cui J,Xiao Z,Qin Y,Zhang Q
Fri Apr 01 00:00:00 EDT 2022
ITGA2 induces STING expression in pancreatic cancer by inducing DNMT1 degradation.
Cellular oncology (Dordrecht)
Meng J,Cai H,Sun Y,Wen S,Wu H,Ren D
Thu Dec 01 00:00:00 EST 2022
ITGA2 induces STING expression in pancreatic cancer by inducing DNMT1 degradation.
Cellular oncology (Dordrecht)
Meng J,Cai H,Sun Y,Wen S,Wu H,Ren D
Thu Dec 01 00:00:00 EST 2022
The Absence of STING Ameliorates Non-Alcoholic Fatty Liver Disease and Reforms Gut Bacterial Community.
Frontiers in immunology
Zhang Q,Chen Q,Yan C,Niu C,Zhou J,Liu J,Song Y,Zhou F,Fan Y,Ren J,Xu H,Zhang B
Tue Jul 19 00:00:00 EDT 2022
The cGAS-STING pathway connects mitochondrial damage to inflammation in burn-induced acute lung injury in rat.
Burns : journal of the International Society for Burn Injuries
Comish PB,Liu MM,Huebinger R,Carlson D,Kang R,Tang D
Tue Feb 01 00:00:00 EST 2022
Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway.
Environmental pollution (Barking, Essex : 1987)
Shen R,Yang K,Cheng X,Guo C,Xing X,Sun H,Liu D,Liu X,Wang D
Sun May 01 00:00:00 EDT 2022
Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway.
Environmental pollution (Barking, Essex : 1987)
Shen R,Yang K,Cheng X,Guo C,Xing X,Sun H,Liu D,Liu X,Wang D
Sun May 01 00:00:00 EDT 2022
SARS-CoV-2 ORF10 antagonizes STING-dependent interferon activation and autophagy.
Journal of medical virology
Han L,Zheng Y,Deng J,Nan ML,Xiao Y,Zhuang MW,Zhang J,Wang W,Gao C,Wang PH
Tue Nov 01 00:00:00 EDT 2022
SARS-CoV-2 ORF10 antagonizes STING-dependent interferon activation and autophagy.
Journal of medical virology
Han L,Zheng Y,Deng J,Nan ML,Xiao Y,Zhuang MW,Zhang J,Wang W,Gao C,Wang PH
Tue Nov 01 00:00:00 EDT 2022
SHP-1 knockdown suppresses mitochondrial biogenesis and aggravates mitochondria-dependent apoptosis induced by all trans retinal through the STING/AMPK pathways.
Molecular medicine (Cambridge, Mass.)
Zhuang X,Ma J,Xu G,Sun Z
Sat Oct 22 00:00:00 EDT 2022
SHP-1 knockdown suppresses mitochondrial biogenesis and aggravates mitochondria-dependent apoptosis induced by all trans retinal through the STING/AMPK pathways.
Molecular medicine (Cambridge, Mass.)
Zhuang X,Ma J,Xu G,Sun Z
Sat Oct 22 00:00:00 EDT 2022
SHP-1 knockdown suppresses mitochondrial biogenesis and aggravates mitochondria-dependent apoptosis induced by all trans retinal through the STING/AMPK pathways.
Molecular medicine (Cambridge, Mass.)
Zhuang X,Ma J,Xu G,Sun Z
Sat Oct 22 00:00:00 EDT 2022
The African swine fever virus protease pS273R inhibits DNA sensing cGAS-STING pathway by targeting IKKε.
Virulence
Luo J,Zhang J,Ni J,Jiang S,Xia N,Guo Y,Shao Q,Cao Q,Zheng W,Chen N,Zhang Q,Chen H,Chen Q,Zhu H,Meurens F,Zhu J
Thu Dec 01 00:00:00 EST 2022
Irradiation combined with PD-L1-/- and autophagy inhibition enhances the antitumor effect of lung cancer via cGAS-STING-mediated T cell activation.
iScience
Zhao X,Hu S,Zeng L,Liu X,Song Y,Zhang Y,Chen Q,Bai Y,Zhang J,Zhang H,Pan Y,Shao C
Fri Aug 19 00:00:00 EDT 2022
Inhibition of cGAS in Paraventricular Nucleus Attenuates Hypertensive Heart Injury Via Regulating Microglial Autophagy.
Molecular neurobiology
Han C,Qian X,Ren X,Zhang S,Hu L,Li J,Huang Y,Huang R,Ooi K,Lin H,Xia C
Tue Nov 01 00:00:00 EDT 2022
Inhibition of cGAS in Paraventricular Nucleus Attenuates Hypertensive Heart Injury Via Regulating Microglial Autophagy.
Molecular neurobiology
Han C,Qian X,Ren X,Zhang S,Hu L,Li J,Huang Y,Huang R,Ooi K,Lin H,Xia C
Tue Nov 01 00:00:00 EDT 2022
Lipid Nanoparticles Delivering Constitutively Active STING mRNA to Stimulate Antitumor Immunity.
International journal of molecular sciences
Liu W,Alameh MG,Yang JF,Xu JR,Lin PJC,Tam YK,Weissman D,You J
Tue Nov 22 00:00:00 EST 2022
Lipid Nanoparticles Delivering Constitutively Active STING mRNA to Stimulate Antitumor Immunity.
International journal of molecular sciences
Liu W,Alameh MG,Yang JF,Xu JR,Lin PJC,Tam YK,Weissman D,You J
Tue Nov 22 00:00:00 EST 2022
Helicobacter pylori actively suppresses innate immune nucleic acid receptors.
Gut microbes
Dooyema SDR,Noto JM,Wroblewski LE,Piazuelo MB,Krishna U,Suarez G,Romero-Gallo J,Delgado AG,Peek RM
Tue Aug 02 00:00:00 EDT 2022
Helicobacter pylori actively suppresses innate immune nucleic acid receptors.
Gut microbes
Dooyema SDR,Noto JM,Wroblewski LE,Piazuelo MB,Krishna U,Suarez G,Romero-Gallo J,Delgado AG,Peek RM
Tue Aug 02 00:00:00 EDT 2022
Helicobacter pylori actively suppresses innate immune nucleic acid receptors.
Gut microbes
Dooyema SDR,Noto JM,Wroblewski LE,Piazuelo MB,Krishna U,Suarez G,Romero-Gallo J,Delgado AG,Peek RM
Tue Aug 02 00:00:00 EDT 2022
Helicobacter pylori actively suppresses innate immune nucleic acid receptors.
Gut microbes
Dooyema SDR,Noto JM,Wroblewski LE,Piazuelo MB,Krishna U,Suarez G,Romero-Gallo J,Delgado AG,Peek RM
Tue Aug 02 00:00:00 EDT 2022
cGAS-STING mediates cytoplasmic mitochondrial-DNA-induced inflammatory signal transduction during accelerated senescence of pancreatic β-cells induced by metabolic stress.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Hu H,Zhao R,He Q,Cui C,Song J,Guo X,Zang N,Yang M,Zou Y,Yang J,Li J,Wang L,Xia L,Wang L,He F,Hou X,Yan F,Chen L
Sun May 01 00:00:00 EDT 2022
cGAS-STING mediates cytoplasmic mitochondrial-DNA-induced inflammatory signal transduction during accelerated senescence of pancreatic β-cells induced by metabolic stress.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Hu H,Zhao R,He Q,Cui C,Song J,Guo X,Zang N,Yang M,Zou Y,Yang J,Li J,Wang L,Xia L,Wang L,He F,Hou X,Yan F,Chen L
Sun May 01 00:00:00 EDT 2022
STING-mediated inflammation contributes to Gao binge ethanol feeding model.
Journal of cellular physiology
Wang L,You HM,Meng HW,Pan XY,Chen X,Bi YH,Zhang YF,Li JJ,Yin NN,Zhang ZW,Huang C,Li J
Tue Feb 01 00:00:00 EST 2022
Microcystin-leucine arginine (MC-LR) induces mouse ovarian inflammation by promoting granulosa cells to produce inflammatory cytokine via activation of cGAS-STING signaling.
Toxicology letters
Liu K,Zhao X,Guo M,Zhu J,Li D,Ding J,Han X,Wu J
Fri Apr 01 00:00:00 EDT 2022
Comprehensive analysis of FKBP4/NR3C1/TMEM173 signaling pathway in triple-negative breast cancer cell and dendritic cell among tumor microenvironment.
Molecular therapy oncolytics
Xiong H,Chen Z,Lin B,Chen W,Li Q,Li Y,Fang M,Wang Y,Zhang H,Lu Y,Bi A,Wu S,Jia Y,Wang X
Thu Mar 17 00:00:00 EDT 2022
CD4 T cell-intrinsic STING signaling controls the differentiation and effector functions of TH1 and TH9 cells.
Journal for immunotherapy of cancer
Benoit-Lizon I,Jacquin E,Rivera Vargas T,Richard C,Roussey A,Dal Zuffo L,Martin T,Melis A,Vinokurova D,Shahoei SH,Baeza Garcia A,Pignol C,Giorgiutti S,Carapito R,Boidot R,Végran F,Flavell RA,Ryffel B,Nelson ER,Soulas-Sprauel P,Lawrence T,Apetoh L
Sat Jan 01 00:00:00 EST 2022
The Lack of STING Impairs the MHC-I Dependent Antigen Presentation and JAK/STAT Signaling in Murine Macrophages.
International journal of molecular sciences
Caiazza C,Brusco T,D'Alessio F,D'Agostino M,Avagliano A,Arcucci A,Ambrosino C,Fiume G,Mallardo M
Thu Nov 17 00:00:00 EST 2022
1,25(OH)2 D3 blocks IFNβ production through regulating STING in epithelial layer of oral lichen planus.
Journal of cellular and molecular medicine
Ge X,Wang Y,Xie H,Li R,Zhang F,Zhao B,Du J
Fri Jul 01 00:00:00 EDT 2022
Gain-of-function genetic screening identifies the antiviral function of TMEM120A via STING activation.
Nature communications
Li S,Qian N,Jiang C,Zu W,Liang A,Li M,Elledge SJ,Tan X
Mon Jan 10 00:00:00 EST 2022
Gain-of-function genetic screening identifies the antiviral function of TMEM120A via STING activation.
Nature communications
Li S,Qian N,Jiang C,Zu W,Liang A,Li M,Elledge SJ,Tan X
Mon Jan 10 00:00:00 EST 2022
Novel CRBN-Recruiting Proteolysis-Targeting Chimeras as Degraders of Stimulator of Interferon Genes with In Vivo Anti-Inflammatory Efficacy.
Journal of medicinal chemistry
Liu J,Yuan L,Ruan Y,Deng B,Yang Z,Ren Y,Li L,Liu T,Zhao H,Mai R,Chen J
Thu May 12 00:00:00 EDT 2022
Deficient DNASE1L3 facilitates neutrophil extracellular traps-induced invasion via cyclic GMP-AMP synthase and the non-canonical NF-κB pathway in diabetic hepatocellular carcinoma.
Clinical & translational immunology
Li N,Zheng X,Chen M,Huang L,Chen L,Huo R,Li X,Huang Y,Sun M,Mai S,Wu Z,Zhang H,Liu J,Yang CT
Fri Apr 29 00:00:00 EDT 2022
Innate immunity mediator STING modulates nascent DNA metabolism at stalled forks in human cells.
Frontiers in molecular biosciences
Lazarchuk P,Nguyen VN,Brunon S,Pavlova MN,Sidorova JM
Wed Aug 30 00:00:00 EDT 2023
Molecular cloning and functional analysis of Macaca mulatta STING.
Developmental and comparative immunology
Zhao M,Zhang H,Sha H,Li H,Wang R
Tue Feb 01 00:00:00 EST 2022
STING Induces Liver Ischemia-Reperfusion Injury by Promoting Calcium-Dependent Caspase 1-GSDMD Processing in Macrophages.
Oxidative medicine and cellular longevity
Wu XY,Chen YJ,Liu CA,Gong JH,Xu XS
Thu Mar 24 00:00:00 EDT 2022
Allosteric inhibition reveals SHP2-mediated tumor immunosuppression in colon cancer by single-cell transcriptomics.
Acta pharmaceutica Sinica. B
Gao J,Wu Z,Zhao M,Zhang R,Li M,Sun D,Cheng H,Qi X,Shen Y,Xu Q,Chen H,Chen D,Sun Y
Sat Jan 01 00:00:00 EST 2022
Harnessing chlorin e6 loaded by functionalized iron oxide nanoparticles linked with glucose for target photodynamic therapy and improving of the immunogenicity of lung cancer.
Journal of cancer research and clinical oncology
Yu TT,Peng XC,Wang MF,Han N,Xu HZ,Li QR,Li LG,Xu X,Ma QL,Liu B,Wang J,Zhao L,Chen X,Li TF
Fri Apr 01 00:00:00 EDT 2022
Harnessing chlorin e6 loaded by functionalized iron oxide nanoparticles linked with glucose for target photodynamic therapy and improving of the immunogenicity of lung cancer.
Journal of cancer research and clinical oncology
Yu TT,Peng XC,Wang MF,Han N,Xu HZ,Li QR,Li LG,Xu X,Ma QL,Liu B,Wang J,Zhao L,Chen X,Li TF
Fri Apr 01 00:00:00 EDT 2022
Clathrin-associated AP-1 controls termination of STING signalling.
Nature
Liu Y,Xu P,Rivara S,Liu C,Ricci J,Ren X,Hurley JH,Ablasser A
Sat Oct 01 00:00:00 EDT 2022
Resveratrol reduces inflammatory response and detrimental effects in chronic cerebral hypoperfusion by down-regulating stimulator of interferon genes/TANK-binding kinase 1/interferon regulatory factor 3 signaling.
Frontiers in aging neuroscience
Kang N,Shi Y,Song J,Gao F,Fan M,Jin W,Gao Y,Lv P
Tue Aug 09 00:00:00 EDT 2022
Resveratrol reduces inflammatory response and detrimental effects in chronic cerebral hypoperfusion by down-regulating stimulator of interferon genes/TANK-binding kinase 1/interferon regulatory factor 3 signaling.
Frontiers in aging neuroscience
Kang N,Shi Y,Song J,Gao F,Fan M,Jin W,Gao Y,Lv P
Tue Aug 09 00:00:00 EDT 2022
HIV-1-induced type I IFNs promote viral latency in macrophages.
Journal of leukocyte biology
Dickey LL,Martins LJ,Planelles V,Hanley TM
Tue Nov 01 00:00:00 EDT 2022
Expression of STING Is Increased in Monocyte-Derived Macrophages and Contributes to Liver Inflammation in Hepatic Ischemia-Reperfusion Injury.
The American journal of pathology
Jiao J,Jiang Y,Qian Y,Liu G,Xu M,Wang F,Sun X,Gao Y,Su L,Shi Y,Kong X
Thu Dec 01 00:00:00 EST 2022
Expression of STING Is Increased in Monocyte-Derived Macrophages and Contributes to Liver Inflammation in Hepatic Ischemia-Reperfusion Injury.
The American journal of pathology
Jiao J,Jiang Y,Qian Y,Liu G,Xu M,Wang F,Sun X,Gao Y,Su L,Shi Y,Kong X
Thu Dec 01 00:00:00 EST 2022
Expression of STING Is Increased in Monocyte-Derived Macrophages and Contributes to Liver Inflammation in Hepatic Ischemia-Reperfusion Injury.
The American journal of pathology
Jiao J,Jiang Y,Qian Y,Liu G,Xu M,Wang F,Sun X,Gao Y,Su L,Shi Y,Kong X
Thu Dec 01 00:00:00 EST 2022
SHR1032, a novel STING agonist, stimulates anti-tumor immunity and directly induces AML apoptosis.
Scientific reports
Song C,Liu D,Liu S,Li D,Horecny I,Zhang X,Li P,Chen L,Miller M,Chowdhury R,Issa M,Shen R,Yan Y,Zhang F,Zhang L,Zhang L,Bai C,Feng J,Zhuang L,Zhang R,Li J,Wilkinson H,Liu J,Tao W
Fri May 20 00:00:00 EDT 2022
Interruption of post-Golgi STING trafficking activates tonic interferon signaling.
Nature communications
Tu X,Chu TT,Jeltema D,Abbott K,Yang K,Xing C,Han J,Dobbs N,Yan N
Tue Nov 15 00:00:00 EST 2022
Interruption of post-Golgi STING trafficking activates tonic interferon signaling.
Nature communications
Tu X,Chu TT,Jeltema D,Abbott K,Yang K,Xing C,Han J,Dobbs N,Yan N
Tue Nov 15 00:00:00 EST 2022
Interruption of post-Golgi STING trafficking activates tonic interferon signaling.
Nature communications
Tu X,Chu TT,Jeltema D,Abbott K,Yang K,Xing C,Han J,Dobbs N,Yan N
Tue Nov 15 00:00:00 EST 2022
Interruption of post-Golgi STING trafficking activates tonic interferon signaling.
Nature communications
Tu X,Chu TT,Jeltema D,Abbott K,Yang K,Xing C,Han J,Dobbs N,Yan N
Tue Nov 15 00:00:00 EST 2022
Role of the cGAS-STING Pathway in Aging-related Endothelial Dysfunction.
Aging and disease
Yu H,Liao K,Hu Y,Lv D,Luo M,Liu Q,Huang L,Luo S
Thu Dec 01 00:00:00 EST 2022
Pharmacological inhibition of the cGAS-STING signaling pathway suppresses microglial M1-polarization in the spinal cord and attenuates neuropathic pain.
Neuropharmacology
Wu W,Zhang X,Wang S,Li T,Hao Q,Li S,Yao W,Sun R
Sat Oct 01 00:00:00 EDT 2022
Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.
Biochemical pharmacology
Ni L,Lin Z,Hu S,Shi Y,Jiang Z,Zhao J,Zhou Y,Wu Y,Tian N,Sun L,Wu A,Pan Z,Zhang X,Wang X
Fri Apr 01 00:00:00 EDT 2022
Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.
Biochemical pharmacology
Ni L,Lin Z,Hu S,Shi Y,Jiang Z,Zhao J,Zhou Y,Wu Y,Tian N,Sun L,Wu A,Pan Z,Zhang X,Wang X
Fri Apr 01 00:00:00 EDT 2022
Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.
Biochemical pharmacology
Ni L,Lin Z,Hu S,Shi Y,Jiang Z,Zhao J,Zhou Y,Wu Y,Tian N,Sun L,Wu A,Pan Z,Zhang X,Wang X
Fri Apr 01 00:00:00 EDT 2022
DNA damage induces STING mediated IL-6-STAT3 survival pathway in triple-negative breast cancer cells and decreased survival of breast cancer patients.
Apoptosis : an international journal on programmed cell death
Vasiyani H,Mane M,Rana K,Shinde A,Roy M,Singh J,Gohel D,Currim F,Srivastava R,Singh R
Thu Dec 01 00:00:00 EST 2022
African Swine Fever Virus Structural Protein p17 Inhibits cGAS-STING Signaling Pathway Through Interacting With STING.
Frontiers in immunology
Zheng W,Xia N,Zhang J,Cao Q,Jiang S,Luo J,Wang H,Chen N,Zhang Q,Meurens F,Zhu J
Tue Jul 19 00:00:00 EDT 2022
African Swine Fever Virus Structural Protein p17 Inhibits cGAS-STING Signaling Pathway Through Interacting With STING.
Frontiers in immunology
Zheng W,Xia N,Zhang J,Cao Q,Jiang S,Luo J,Wang H,Chen N,Zhang Q,Meurens F,Zhu J
Tue Jul 19 00:00:00 EDT 2022
Porcine cGAS-STING signaling induced autophagy inhibits STING downstream IFN and apoptosis.
Frontiers in immunology
Xia N,Zheng W,Jiang S,Cao Q,Luo J,Zhang J,Xu Y,Sun S,Zhang K,Chen N,Meurens F,Zhu J
Tue Nov 01 00:00:00 EDT 2022
Mitochondrial cristae architecture protects against mtDNA release and inflammation.
Cell reports
He B,Yu H,Liu S,Wan H,Fu S,Liu S,Yang J,Zhang Z,Huang H,Li Q,Wang F,Jiang Z,Liu Q,Jiang H
Tue Dec 06 00:00:00 EST 2022
MPYS Modulates Fatty Acid Metabolism and Immune Tolerance at Homeostasis Independent of Type I IFNs.
Journal of immunology (Baltimore, Md. : 1950)
Mansouri S,Gogoi H,Patel S,Katikaneni DS,Singh A,Aybar-Torres A,de Lartigue G,Jin L
Thu Dec 01 00:00:00 EST 2022
The Porcine and Chicken Innate DNA Sensing cGAS-STING-IRF Signaling Axes Exhibit Differential Species Specificity.
Journal of immunology (Baltimore, Md. : 1950)
Jiang S,Luo J,Zhang Y,Cao Q,Wang Y,Xia N,Zheng W,Chen N,Meurens F,Wu H,Zhu J
Fri Jul 15 00:00:00 EDT 2022
Baicalein-loaded silk fibroin peptide nanofibers protect against cisplatin-induced acute kidney injury: Fabrication, characterization and mechanism.
International journal of pharmaceutics
Liu S,Gao X,Wang Y,Wang J,Qi X,Dong K,Shi D,Wu X,Guo C
Sat Oct 15 00:00:00 EDT 2022
Baicalein-loaded silk fibroin peptide nanofibers protect against cisplatin-induced acute kidney injury: Fabrication, characterization and mechanism.
International journal of pharmaceutics
Liu S,Gao X,Wang Y,Wang J,Qi X,Dong K,Shi D,Wu X,Guo C
Sat Oct 15 00:00:00 EDT 2022
Baicalein-loaded silk fibroin peptide nanofibers protect against cisplatin-induced acute kidney injury: Fabrication, characterization and mechanism.
International journal of pharmaceutics
Liu S,Gao X,Wang Y,Wang J,Qi X,Dong K,Shi D,Wu X,Guo C
Sat Oct 15 00:00:00 EDT 2022
Baicalein-loaded silk fibroin peptide nanofibers protect against cisplatin-induced acute kidney injury: Fabrication, characterization and mechanism.
International journal of pharmaceutics
Liu S,Gao X,Wang Y,Wang J,Qi X,Dong K,Shi D,Wu X,Guo C
Sat Oct 15 00:00:00 EDT 2022
Baicalein-loaded silk fibroin peptide nanofibers protect against cisplatin-induced acute kidney injury: Fabrication, characterization and mechanism.
International journal of pharmaceutics
Liu S,Gao X,Wang Y,Wang J,Qi X,Dong K,Shi D,Wu X,Guo C
Sat Oct 15 00:00:00 EDT 2022
Baicalein-loaded silk fibroin peptide nanofibers protect against cisplatin-induced acute kidney injury: Fabrication, characterization and mechanism.
International journal of pharmaceutics
Liu S,Gao X,Wang Y,Wang J,Qi X,Dong K,Shi D,Wu X,Guo C
Sat Oct 15 00:00:00 EDT 2022
UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum.
EMBO reports
Song P,Yang W,Lou KF,Dong H,Zhang H,Wang B,Chen D
Mon Nov 07 00:00:00 EST 2022
UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum.
EMBO reports
Song P,Yang W,Lou KF,Dong H,Zhang H,Wang B,Chen D
Mon Nov 07 00:00:00 EST 2022
STING Contributes to Cancer-Induced Bone Pain by Promoting M1 Polarization of Microglia in the Medial Prefrontal Cortex.
Cancers
Zhang X,Li X,Wang W,Zhang Y,Gong Z,Peng Y,Wu J,You X
Sat Oct 22 00:00:00 EDT 2022
STING Contributes to Cancer-Induced Bone Pain by Promoting M1 Polarization of Microglia in the Medial Prefrontal Cortex.
Cancers
Zhang X,Li X,Wang W,Zhang Y,Gong Z,Peng Y,Wu J,You X
Sat Oct 22 00:00:00 EDT 2022
STING expression is an independent prognostic factor in patients with mycosis fungoides.
Scientific reports
Takayanagi-Hara R,Sawada Y,Sugino H,Minokawa Y,Kawahara-Nanamori H,Itamura M,Tashiro T,Kaneoka A,Saito-Sasaki N,Yamamoto K,Okada E
Tue Jul 26 00:00:00 EDT 2022
Targeting KDM4C enhances CD8+ T cell mediated antitumor immunity by activating chemokine CXCL10 transcription in lung cancer.
Journal for immunotherapy of cancer
Jie X,Chen Y,Zhao Y,Yang X,Xu Y,Wang J,Meng R,Zhang S,Dong X,Zhang T,Yang K,Xu S,Wu G
Tue Feb 01 00:00:00 EST 2022
Human Atheromatous Plaques Expressed Sensing Adaptor STING, a Potential Role in Vascular Inflammation Pathogenesis.
Thrombosis and haemostasis
Pallarés J,Torreguitart N,Arqué G,Portero-Otin M,Purroy F
Thu Sep 01 00:00:00 EDT 2022
XBP1 deficiency promotes hepatocyte pyroptosis by impairing mitophagy to activate mtDNA-cGAS-STING signaling in macrophages during acute liver injury.
Redox biology
Liu Z,Wang M,Wang X,Bu Q,Wang Q,Su W,Li L,Zhou H,Lu L
Wed Jun 01 00:00:00 EDT 2022
Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity.
Cell research
Gao Y,Zheng X,Chang B,Lin Y,Huang X,Wang W,Ding S,Zhan W,Wang S,Xiao B,Huo L,Yu Y,Chen Y,Gong R,Wu Y,Zhang R,Zhong L,Wang X,Chen Q,Gao S,Jiang Z,Wei D,Kang T
Thu Dec 01 00:00:00 EST 2022
Macrophage targeted triptolide micelles capable of cGAS-STING pathway inhibition for rheumatoid arthritis treatment.
Journal of drug targeting
Xu A,Yang R,Zhang M,Wang X,Di Y,Jiang B,Di Y,Zhou Z,Zhou L
Tue Nov 01 00:00:00 EDT 2022
Macrophage targeted triptolide micelles capable of cGAS-STING pathway inhibition for rheumatoid arthritis treatment.
Journal of drug targeting
Xu A,Yang R,Zhang M,Wang X,Di Y,Jiang B,Di Y,Zhou Z,Zhou L
Tue Nov 01 00:00:00 EDT 2022
The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages.
Cell death & disease
Wu J,Liu Q,Zhang X,Tan M,Li X,Liu P,Wu L,Jiao F,Lin Z,Wu X,Wang X,Zhao Y,Ren J
Thu Jul 28 00:00:00 EDT 2022
The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages.
Cell death & disease
Wu J,Liu Q,Zhang X,Tan M,Li X,Liu P,Wu L,Jiao F,Lin Z,Wu X,Wang X,Zhao Y,Ren J
Thu Jul 28 00:00:00 EDT 2022
The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages.
Cell death & disease
Wu J,Liu Q,Zhang X,Tan M,Li X,Liu P,Wu L,Jiao F,Lin Z,Wu X,Wang X,Zhao Y,Ren J
Thu Jul 28 00:00:00 EDT 2022
The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages.
Cell death & disease
Wu J,Liu Q,Zhang X,Tan M,Li X,Liu P,Wu L,Jiao F,Lin Z,Wu X,Wang X,Zhao Y,Ren J
Thu Jul 28 00:00:00 EDT 2022
The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages.
Cell death & disease
Wu J,Liu Q,Zhang X,Tan M,Li X,Liu P,Wu L,Jiao F,Lin Z,Wu X,Wang X,Zhao Y,Ren J
Thu Jul 28 00:00:00 EDT 2022
The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages.
Cell death & disease
Wu J,Liu Q,Zhang X,Tan M,Li X,Liu P,Wu L,Jiao F,Lin Z,Wu X,Wang X,Zhao Y,Ren J
Thu Jul 28 00:00:00 EDT 2022
Activation of cGAS-STING Pathway Is Associated with MSI-H Stage IV Colorectal Cancer.
Cancers
Kunac N,Degoricija M,Viculin J,Omerović J,Terzić J,Vilović K,Korac-Prlic J
Fri Dec 30 00:00:00 EST 2022
GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.
Oncogene
Xu H,Jin J,Chen Y,Wu G,Zhu H,Wang Q,Wang J,Li S,Grigore FN,Ma J,Chen CC,Lan Q,Li M
Fri Jul 01 00:00:00 EDT 2022
GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.
Oncogene
Xu H,Jin J,Chen Y,Wu G,Zhu H,Wang Q,Wang J,Li S,Grigore FN,Ma J,Chen CC,Lan Q,Li M
Fri Jul 01 00:00:00 EDT 2022
GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.
Oncogene
Xu H,Jin J,Chen Y,Wu G,Zhu H,Wang Q,Wang J,Li S,Grigore FN,Ma J,Chen CC,Lan Q,Li M
Fri Jul 01 00:00:00 EDT 2022
GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.
Oncogene
Xu H,Jin J,Chen Y,Wu G,Zhu H,Wang Q,Wang J,Li S,Grigore FN,Ma J,Chen CC,Lan Q,Li M
Fri Jul 01 00:00:00 EDT 2022
Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity.
PLoS pathogens
Kong Z,Yin H,Wang F,Liu Z,Luan X,Sun L,Liu W,Shang Y
Sun May 01 00:00:00 EDT 2022
Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity.
PLoS pathogens
Kong Z,Yin H,Wang F,Liu Z,Luan X,Sun L,Liu W,Shang Y
Sun May 01 00:00:00 EDT 2022
Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity.
PLoS pathogens
Kong Z,Yin H,Wang F,Liu Z,Luan X,Sun L,Liu W,Shang Y
Sun May 01 00:00:00 EDT 2022
Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity.
PLoS pathogens
Kong Z,Yin H,Wang F,Liu Z,Luan X,Sun L,Liu W,Shang Y
Sun May 01 00:00:00 EDT 2022
Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity.
PLoS pathogens
Kong Z,Yin H,Wang F,Liu Z,Luan X,Sun L,Liu W,Shang Y
Sun May 01 00:00:00 EDT 2022
Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity.
PLoS pathogens
Kong Z,Yin H,Wang F,Liu Z,Luan X,Sun L,Liu W,Shang Y
Sun May 01 00:00:00 EDT 2022
Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity.
PLoS pathogens
Kong Z,Yin H,Wang F,Liu Z,Luan X,Sun L,Liu W,Shang Y
Sun May 01 00:00:00 EDT 2022
Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity.
PLoS pathogens
Kong Z,Yin H,Wang F,Liu Z,Luan X,Sun L,Liu W,Shang Y
Sun May 01 00:00:00 EDT 2022
Pseudorabies virus tegument protein UL13 recruits RNF5 to inhibit STING-mediated antiviral immunity.
PLoS pathogens
Kong Z,Yin H,Wang F,Liu Z,Luan X,Sun L,Liu W,Shang Y
Sun May 01 00:00:00 EDT 2022
STING activation promotes inflammatory response and delays skin wound healing in diabetic mice.
Biochemical and biophysical research communications
Feng Z,Zang C,Zhang L,Yin S,Zhuang Q,Wang X
Thu Jun 30 00:00:00 EDT 2022
Tonic prime-boost of STING signalling mediates Niemann-Pick disease type C.
Nature
Chu TT,Tu X,Yang K,Wu J,Repa JJ,Yan N
Sun Aug 01 00:00:00 EDT 2021
eccDNAs are apoptotic products with high innate immunostimulatory activity.
Nature
Wang Y,Wang M,Djekidel MN,Chen H,Liu D,Alt FW,Zhang Y
Mon Nov 01 00:00:00 EDT 2021
The analog of cGAMP, c-di-AMP, activates STING mediated cell death pathway in estrogen-receptor negative breast cancer cells.
Apoptosis : an international journal on programmed cell death
Vasiyani H,Shinde A,Roy M,Mane M,Singh K,Singh J,Gohel D,Currim F,Vaidya K,Chhabria M,Singh R
Tue Jun 01 00:00:00 EDT 2021
STING Contributes to Host Defense Against Staphylococcus aureus Pneumonia Through Suppressing Necroptosis.
Frontiers in immunology
Liu ZZ,Yang YJ,Zhou CK,Yan SQ,Ma K,Gao Y,Chen W
Tue Oct 26 00:00:00 EDT 2021
Mutant p53 suppresses innate immune signaling to promote tumorigenesis.
Cancer cell
Ghosh M,Saha S,Bettke J,Nagar R,Parrales A,Iwakuma T,van der Velden AWM,Martinez LA
Mon Apr 12 00:00:00 EDT 2021
The Innate Immune DNA Sensing cGAS-STING Signaling Pathway Mediates Anti-PRRSV Function.
Viruses
Xu Y,Zhang Y,Sun S,Luo J,Jiang S,Zhang J,Liu X,Shao Q,Cao Q,Zheng W,Chen N,Meurens F,Zhu J
Tue Sep 14 00:00:00 EDT 2021
The cGAS-STING signaling pathway contributes to the inflammatory response and autophagy in Aspergillus fumigatus keratitis.
Experimental eye research
Han F,Guo H,Wang L,Zhang Y,Sun L,Dai C,Wu X
Fri Jan 01 00:00:00 EST 2021
Negative Regulation of RNF90 on RNA Virus-Triggered Antiviral Immune Responses Targeting MAVS.
Frontiers in immunology
Yang B,Zhang G,Qin X,Huang Y,Ren X,Sun J,Ma S,Liu Y,Song D,Liu Y,Cui Y,Wang H,Wang J
Thu Dec 23 00:00:00 EST 2021
The novel STING antagonist H151 ameliorates cisplatin-induced acute kidney injury and mitochondrial dysfunction.
American journal of physiology. Renal physiology
Gong W,Lu L,Zhou Y,Liu J,Ma H,Fu L,Huang S,Zhang Y,Zhang A,Jia Z
Thu Apr 01 00:00:00 EDT 2021
The novel STING antagonist H151 ameliorates cisplatin-induced acute kidney injury and mitochondrial dysfunction.
American journal of physiology. Renal physiology
Gong W,Lu L,Zhou Y,Liu J,Ma H,Fu L,Huang S,Zhang Y,Zhang A,Jia Z
Thu Apr 01 00:00:00 EDT 2021
USP18 and USP20 restrict oHSV-1 replication in resistant human oral squamous carcinoma cell line SCC9 and affect the viability of SCC9 cells.
Molecular therapy oncolytics
Lu R,Wu G,Chen M,Ji D,Liu Y,Zhou GG,Fu W
Fri Dec 17 00:00:00 EST 2021
USP18 and USP20 restrict oHSV-1 replication in resistant human oral squamous carcinoma cell line SCC9 and affect the viability of SCC9 cells.
Molecular therapy oncolytics
Lu R,Wu G,Chen M,Ji D,Liu Y,Zhou GG,Fu W
Fri Dec 17 00:00:00 EST 2021
A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA.
Cell reports
Sun H,Huang Y,Mei S,Xu F,Liu X,Zhao F,Yin L,Zhang D,Wei L,Wu C,Ma S,Wang J,Cen S,Liang C,Hu S,Guo F
Tue Jan 05 00:00:00 EST 2021
Synergistic Activation of Antitumor Immunity by a Particulate Therapeutic Vaccine.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Mai J,Li Z,Xia X,Zhang J,Li J,Liu H,Shen J,Ramirez M,Li F,Li Z,Yokoi K,Liu X,Mittendorf EA,Ferrari M,Shen H
Tue Jun 01 00:00:00 EDT 2021
The DJ1-Nrf2-STING axis mediates the neuroprotective effects of Withaferin A in Parkinson's disease.
Cell death and differentiation
Zhao M,Wang B,Zhang C,Su Z,Guo B,Zhao Y,Zheng R
Sun Aug 01 00:00:00 EDT 2021
The DJ1-Nrf2-STING axis mediates the neuroprotective effects of Withaferin A in Parkinson's disease.
Cell death and differentiation
Zhao M,Wang B,Zhang C,Su Z,Guo B,Zhao Y,Zheng R
Sun Aug 01 00:00:00 EDT 2021
FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates.
Scientific reports
Schlütermann D,Berleth N,Deitersen J,Wallot-Hieke N,Friesen O,Wu W,Stuhldreier F,Sun Y,Berning L,Friedrich A,Mendiburo MJ,Peter C,Wiek C,Hanenberg H,Stefanski A,Stühler K,Stork B
Mon Jul 05 00:00:00 EDT 2021
Activation of STING Signaling Pathway Effectively Blocks Human Coronavirus Infection.
Journal of virology
Liu W,Reyes HM,Yang JF,Li Y,Stewart KM,Basil MC,Lin SM,Katzen J,Morrisey EE,Weiss SR,You J
Mon May 24 00:00:00 EDT 2021
Brucella spp. Omp25 Promotes Proteasome-Mediated cGAS Degradation to Attenuate IFN-β Production.
Frontiers in microbiology
Li R,Liu W,Yin X,Zheng F,Wang Z,Wu X,Zhang X,Du Q,Huang Y,Tong D
Tue Aug 17 00:00:00 EDT 2021
Extracellular vesicles package dsDNA to aggravate Crohn's disease by activating the STING pathway.
Cell death & disease
Zhao F,Zheng T,Gong W,Wu J,Xie H,Li W,Zhang R,Liu P,Liu J,Wu X,Zhao Y,Ren J
Fri Aug 27 00:00:00 EDT 2021
Activation of the cGAS-STING signaling pathway in adenomyosis patients.
Immunity, inflammation and disease
Lin Y,Wang L,Ye M,Yu KN,Sun X,Xue M,Deng X
Wed Sep 01 00:00:00 EDT 2021
Chromosome aberrations induced by the non-mutagenic carcinogen acetamide involve in rat hepatocarcinogenesis through micronucleus formation in hepatocytes.
Archives of toxicology
Nakamura K,Ishii Y,Takasu S,Nohmi T,Shibutani M,Ogawa K
Sun Aug 01 00:00:00 EDT 2021
Staphylococcus aureus Induces IFN-β Production via a CARMA3-Independent Mechanism.
Pathogens (Basel, Switzerland)
Zhou Y,Zhao S,Gao X,Jiang S,Ma J,Wang R,Li Q,Qin L,Tong Z,Wu J,Zhao J
Thu Mar 04 00:00:00 EST 2021
A cell-free assay implicates a role of sphingomyelin and cholesterol in STING phosphorylation.
Scientific reports
Takahashi K,Niki T,Ogawa E,Fumika K,Nishioka Y,Sawa M,Arai H,Mukai K,Taguchi T
Mon Jun 07 00:00:00 EDT 2021
A cell-free assay implicates a role of sphingomyelin and cholesterol in STING phosphorylation.
Scientific reports
Takahashi K,Niki T,Ogawa E,Fumika K,Nishioka Y,Sawa M,Arai H,Mukai K,Taguchi T
Mon Jun 07 00:00:00 EDT 2021
Efficient Delivery of Chlorin e6 by Polyglycerol-Coated Iron Oxide Nanoparticles with Conjugated Doxorubicin for Enhanced Photodynamic Therapy of Melanoma.
Molecular pharmaceutics
Li TF,Xu HZ,Xu YH,Yu TT,Tang JM,Li K,Wang C,Peng XC,Li QR,Sang XY,Zheng MY,Liu Y,Zhao L,Chen X
Mon Sep 06 00:00:00 EDT 2021
Efficient Delivery of Chlorin e6 by Polyglycerol-Coated Iron Oxide Nanoparticles with Conjugated Doxorubicin for Enhanced Photodynamic Therapy of Melanoma.
Molecular pharmaceutics
Li TF,Xu HZ,Xu YH,Yu TT,Tang JM,Li K,Wang C,Peng XC,Li QR,Sang XY,Zheng MY,Liu Y,Zhao L,Chen X
Mon Sep 06 00:00:00 EDT 2021
Conjugation with nanodiamonds via hydrazone bond fundamentally alters intracellular distribution and activity of doxorubicin.
International journal of pharmaceutics
Yuan SJ,Wang C,Xu HZ,Liu Y,Zheng MY,Li K,Sun SK,Komatsu N,Zhao L,Chen X
Sun Sep 05 00:00:00 EDT 2021
Conjugation with nanodiamonds via hydrazone bond fundamentally alters intracellular distribution and activity of doxorubicin.
International journal of pharmaceutics
Yuan SJ,Wang C,Xu HZ,Liu Y,Zheng MY,Li K,Sun SK,Komatsu N,Zhao L,Chen X
Sun Sep 05 00:00:00 EDT 2021
Screening of Porcine Innate Immune Adaptor Signaling Revealed Several Anti-PRRSV Signaling Pathways.
Vaccines
Xu Y,Ye M,Zhang Y,Sun S,Luo J,Jiang S,Zhang J,Liu X,Shao Q,Cao Q,Zheng W,Meurens F,Chen N,Zhu J
Thu Oct 14 00:00:00 EDT 2021
Transfected DNA is targeted by STING-mediated restriction.
Biochemical and biophysical research communications
Gu C,Ming L,Tao S,Luo M,Guo H,Xie Y,Liu J,Shen Z
Fri Apr 16 00:00:00 EDT 2021
A Versatile Nanoplatform for Broad-Spectrum Immunotherapy by Reversing the Tumor Microenvironment.
ACS applied materials & interfaces
Chen A,Yang F,Kuang J,Xiong Y,Mi BB,Zhou Y,Hu JJ,Song SJ,Wan T,Wan ZZ,Huang HY,Li XR,Song W,Qiu WX
Wed Sep 29 00:00:00 EDT 2021
Pharmacological activation of STING blocks SARS-CoV-2 infection.
Science immunology
Li M,Ferretti M,Ying B,Descamps H,Lee E,Dittmar M,Lee JS,Whig K,Kamalia B,Dohnalová L,Uhr G,Zarkoob H,Chen YC,Ramage H,Ferrer M,Lynch K,Schultz DC,Thaiss CA,Diamond MS,Cherry S
Tue May 18 00:00:00 EDT 2021
Arginine methyltransferase PRMT5 negatively regulates cGAS-mediated antiviral immune response.
Science advances
Ma D,Yang M,Wang Q,Sun C,Shi H,Jing W,Bi Y,Shen X,Ma X,Qin Z,Lin Y,Zhu L,Zhao Y,Cheng Y,Han L
Mon Mar 01 00:00:00 EST 2021
USP18 positively regulates innate antiviral immunity by promoting K63-linked polyubiquitination of MAVS.
Nature communications
Hou J,Han L,Zhao Z,Liu H,Zhang L,Ma C,Yi F,Liu B,Zheng Y,Gao C
Thu May 20 00:00:00 EDT 2021
Homeostatic regulation of STING protein at the resting state by stabilizer TOLLIP.
Nature immunology
Pokatayev V,Yang K,Tu X,Dobbs N,Wu J,Kalb RG,Yan N
Sat Feb 01 00:00:00 EST 2020
Galectin-9 promotes a suppressive microenvironment in human cancer by enhancing STING degradation.
Oncogenesis
Zhang CX,Huang DJ,Baloche V,Zhang L,Xu JX,Li BW,Zhao XR,He J,Mai HQ,Chen QY,Zhang XS,Busson P,Cui J,Li J
Mon Jul 06 00:00:00 EDT 2020
mtDNA-STING pathway promotes necroptosis-dependent enterocyte injury in intestinal ischemia reperfusion.
Cell death & disease
Zhang X,Wu J,Liu Q,Li X,Li S,Chen J,Hong Z,Wu X,Zhao Y,Ren J
Fri Dec 11 00:00:00 EST 2020
Stimulator of interferon genes (STING) is an essential proviral host factor for human rhinovirus species A and C.
Proceedings of the National Academy of Sciences of the United States of America
McKnight KL,Swanson KV,Austgen K,Richards C,Mitchell JK,McGivern DR,Fritch E,Johnson J,Remlinger K,Magid-Slav M,Kapustina M,You S,Lemon SM
Tue Nov 03 00:00:00 EST 2020
Stimulator of interferon genes (STING) is an essential proviral host factor for human rhinovirus species A and C.
Proceedings of the National Academy of Sciences of the United States of America
McKnight KL,Swanson KV,Austgen K,Richards C,Mitchell JK,McGivern DR,Fritch E,Johnson J,Remlinger K,Magid-Slav M,Kapustina M,You S,Lemon SM
Tue Nov 03 00:00:00 EST 2020
Interferon-independent STING signaling promotes resistance to HSV-1 in vivo.
Nature communications
Yamashiro LH,Wilson SC,Morrison HM,Karalis V,Chung JJ,Chen KJ,Bateup HS,Szpara ML,Lee AY,Cox JS,Vance RE
Tue Jul 07 00:00:00 EDT 2020
Targeting macrophage priming by polyphyllin VII triggers anti-tumor immunity via STING-governed cytotoxic T-cell infiltration in lung cancer.
Scientific reports
Yu J,Deng H,Xu Z
Mon Dec 07 00:00:00 EST 2020
Autophagic degradation of PML promotes susceptibility to HSV-1 by stress-induced corticosterone.
Theranostics
Li W,Luo Z,Yan CY,Wang XH,He ZJ,Ouyang SH,Yan C,Liu LF,Zhou QQ,Mu HL,Gong HB,Duan WJ,Liang L,Kurihara H,Feng D,Li YF,He RR
Tue Jun 01 00:00:00 EDT 2021
Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage.
Journal of neuroinflammation
Peng Y,Zhuang J,Ying G,Zeng H,Zhou H,Cao Y,Chen H,Xu C,Fu X,Xu H,Li J,Cao S,Chen J,Gu C,Yan F,Chen G
Mon May 25 00:00:00 EDT 2020
Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage.
Journal of neuroinflammation
Peng Y,Zhuang J,Ying G,Zeng H,Zhou H,Cao Y,Chen H,Xu C,Fu X,Xu H,Li J,Cao S,Chen J,Gu C,Yan F,Chen G
Mon May 25 00:00:00 EDT 2020
Reactive oxygen species oxidize STING and suppress interferon production.
eLife
Tao L,Lemoff A,Wang G,Zarek C,Lowe A,Yan N,Reese TA
Fri Sep 04 00:00:00 EDT 2020
Reactive oxygen species oxidize STING and suppress interferon production.
eLife
Tao L,Lemoff A,Wang G,Zarek C,Lowe A,Yan N,Reese TA
Fri Sep 04 00:00:00 EDT 2020
TBC1D9 regulates TBK1 activation through Ca2+ signaling in selective autophagy.
Nature communications
Nozawa T,Sano S,Minowa-Nozawa A,Toh H,Nakajima S,Murase K,Aikawa C,Nakagawa I
Fri Feb 07 00:00:00 EST 2020
Metformin activates the STING/IRF3/IFN-β pathway by inhibiting AKT phosphorylation in pancreatic cancer.
American journal of cancer research
Ren D,Qin G,Zhao J,Sun Y,Zhang B,Li D,Wang B,Jin X,Wu H
Tue Oct 13 00:00:00 EDT 2020
SPHK2-Generated S1P in CD11b+ Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages.
Cell reports
Joshi JC,Joshi B,Rochford I,Rayees S,Akhter MZ,Baweja S,Chava KR,Tauseef M,Abdelkarim H,Natarajan V,Gaponenko V,Mehta D
Tue Mar 24 00:00:00 EDT 2020
Long non-coding RNA MALAT1 targeting STING transcription promotes bronchopulmonary dysplasia through regulation of CREB.
Journal of cellular and molecular medicine
Chen JH,Feng DD,Chen YF,Yang CX,Juan CX,Cao Q,Chen X,Liu S,Zhou GP
Tue Sep 01 00:00:00 EDT 2020
Long non-coding RNA MALAT1 targeting STING transcription promotes bronchopulmonary dysplasia through regulation of CREB.
Journal of cellular and molecular medicine
Chen JH,Feng DD,Chen YF,Yang CX,Juan CX,Cao Q,Chen X,Liu S,Zhou GP
Tue Sep 01 00:00:00 EDT 2020
Long non-coding RNA MALAT1 targeting STING transcription promotes bronchopulmonary dysplasia through regulation of CREB.
Journal of cellular and molecular medicine
Chen JH,Feng DD,Chen YF,Yang CX,Juan CX,Cao Q,Chen X,Liu S,Zhou GP
Tue Sep 01 00:00:00 EDT 2020
RNF90 negatively regulates cellular antiviral responses by targeting MITA for degradation.
PLoS pathogens
Yang B,Liu Y,Cui Y,Song D,Zhang G,Ma S,Liu Y,Chen M,Chen F,Wang H,Wang J
Sun Mar 01 00:00:00 EST 2020
Redox homeostasis maintained by GPX4 facilitates STING activation.
Nature immunology
Jia M,Qin D,Zhao C,Chai L,Yu Z,Wang W,Tong L,Lv L,Wang Y,Rehwinkel J,Yu J,Zhao W
Wed Jul 01 00:00:00 EDT 2020
Redox homeostasis maintained by GPX4 facilitates STING activation.
Nature immunology
Jia M,Qin D,Zhao C,Chai L,Yu Z,Wang W,Tong L,Lv L,Wang Y,Rehwinkel J,Yu J,Zhao W
Wed Jul 01 00:00:00 EDT 2020
Mitochondrial DNA drives noncanonical inflammation activation via cGAS-STING signaling pathway in retinal microvascular endothelial cells.
Cell communication and signaling : CCS
Guo Y,Gu R,Gan D,Hu F,Li G,Xu G
Wed Oct 28 00:00:00 EDT 2020
STING signaling remodels the tumor microenvironment by antagonizing myeloid-derived suppressor cell expansion.
Cell death and differentiation
Zhang CX,Ye SB,Ni JJ,Cai TT,Liu YN,Huang DJ,Mai HQ,Chen QY,He J,Zhang XS,Zeng YX,Li J,Cui J
Fri Nov 01 00:00:00 EDT 2019
cGAS/STING/TBK1/IRF3 Signaling Pathway Activates BMDCs Maturation Following Mycobacterium bovis Infection.
International journal of molecular sciences
Li Q,Liu C,Yue R,El-Ashram S,Wang J,He X,Zhao D,Zhou X,Xu L
Tue Feb 19 00:00:00 EST 2019
Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury.
Cell reports
Maekawa H,Inoue T,Ouchi H,Jao TM,Inoue R,Nishi H,Fujii R,Ishidate F,Tanaka T,Tanaka Y,Hirokawa N,Nangaku M,Inagi R
Tue Oct 29 00:00:00 EDT 2019
Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury.
Cell reports
Maekawa H,Inoue T,Ouchi H,Jao TM,Inoue R,Nishi H,Fujii R,Ishidate F,Tanaka T,Tanaka Y,Hirokawa N,Nangaku M,Inagi R
Tue Oct 29 00:00:00 EDT 2019
Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury.
Cell reports
Maekawa H,Inoue T,Ouchi H,Jao TM,Inoue R,Nishi H,Fujii R,Ishidate F,Tanaka T,Tanaka Y,Hirokawa N,Nangaku M,Inagi R
Tue Oct 29 00:00:00 EDT 2019
Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury.
Cell reports
Maekawa H,Inoue T,Ouchi H,Jao TM,Inoue R,Nishi H,Fujii R,Ishidate F,Tanaka T,Tanaka Y,Hirokawa N,Nangaku M,Inagi R
Tue Oct 29 00:00:00 EDT 2019
Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury.
Cell reports
Maekawa H,Inoue T,Ouchi H,Jao TM,Inoue R,Nishi H,Fujii R,Ishidate F,Tanaka T,Tanaka Y,Hirokawa N,Nangaku M,Inagi R
Tue Oct 29 00:00:00 EDT 2019
Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury.
Cell reports
Maekawa H,Inoue T,Ouchi H,Jao TM,Inoue R,Nishi H,Fujii R,Ishidate F,Tanaka T,Tanaka Y,Hirokawa N,Nangaku M,Inagi R
Tue Oct 29 00:00:00 EDT 2019
Autophagy induction via STING trafficking is a primordial function of the cGAS pathway.
Nature
Gui X,Yang H,Li T,Tan X,Shi P,Li M,Du F,Chen ZJ
Fri Mar 01 00:00:00 EST 2019
Autophagy induction via STING trafficking is a primordial function of the cGAS pathway.
Nature
Gui X,Yang H,Li T,Tan X,Shi P,Li M,Du F,Chen ZJ
Fri Mar 01 00:00:00 EST 2019
PKR-dependent cytosolic cGAS foci are necessary for intracellular DNA sensing.
Science signaling
Hu S,Sun H,Yin L,Li J,Mei S,Xu F,Wu C,Liu X,Zhao F,Zhang D,Huang Y,Ren L,Cen S,Wang J,Liang C,Guo F
Tue Nov 26 00:00:00 EST 2019
USP49 negatively regulates cellular antiviral responses via deconjugating K63-linked ubiquitination of MITA.
PLoS pathogens
Ye L,Zhang Q,Liuyu T,Xu Z,Zhang MX,Luo MH,Zeng WB,Zhu Q,Lin D,Zhong B
Mon Apr 01 00:00:00 EDT 2019
DNA Sensor IFI204 Contributes to Host Defense Against Staphylococcus aureus Infection in Mice.
Frontiers in immunology
Chen W,Yu SX,Zhou FH,Zhang XJ,Gao WY,Li KY,Liu ZZ,Han WY,Yang YJ
Thu Sep 10 00:00:00 EDT 2020
DNA Sensor IFI204 Contributes to Host Defense Against Staphylococcus aureus Infection in Mice.
Frontiers in immunology
Chen W,Yu SX,Zhou FH,Zhang XJ,Gao WY,Li KY,Liu ZZ,Han WY,Yang YJ
Thu Sep 10 00:00:00 EDT 2020
The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling.
Science (New York, N.Y.)
Abdel-Nour M,Carneiro LAM,Downey J,Tsalikis J,Outlioua A,Prescott D,Da Costa LS,Hovingh ES,Farahvash A,Gaudet RG,Molinaro R,van Dalen R,Lau CCY,Azimi FC,Escalante NK,Trotman-Grant A,Lee JE,Gray-Owen SD,Divangahi M,Chen JJ,Philpott DJ,Arnoult D,Girardin SE
Fri Jul 05 00:00:00 EDT 2019
Lung adenocarcinoma-intrinsic GBE1 signaling inhibits anti-tumor immunity.
Molecular cancer
Li L,Yang L,Cheng S,Fan Z,Shen Z,Xue W,Zheng Y,Li F,Wang D,Zhang K,Lian J,Wang D,Zhu Z,Zhao J,Zhang Y
Thu Jun 20 00:00:00 EDT 2019
African Swine Fever Virus Armenia/07 Virulent Strain Controls Interferon Beta Production through the cGAS-STING Pathway.
Journal of virology
García-Belmonte R,Pérez-Núñez D,Pittau M,Richt JA,Revilla Y
Sat Jun 15 00:00:00 EDT 2019
Tandem Mass Tag Proteomic Analysis of in Vitro and in Vivo Models of Cutaneous Leishmaniasis Reveals Parasite-Specific and Nonspecific Modulation of Proteins in the Host.
ACS infectious diseases
Negrão F,Diedrich JK,Giorgio S,Eberlin MN,Yates JR
Fri Dec 13 00:00:00 EST 2019
Innate responses to gene knockouts impact overlapping gene networks and vary with respect to resistance to viral infection.
Proceedings of the National Academy of Sciences of the United States of America
Liu Y,Liu Y,Wu J,Roizman B,Zhou GG
Tue Apr 03 00:00:00 EDT 2018
Innate responses to gene knockouts impact overlapping gene networks and vary with respect to resistance to viral infection.
Proceedings of the National Academy of Sciences of the United States of America
Liu Y,Liu Y,Wu J,Roizman B,Zhou GG
Tue Apr 03 00:00:00 EDT 2018
Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS.
Journal of virology
Burgess HM,Mohr I
Wed Aug 01 00:00:00 EDT 2018
Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS.
Journal of virology
Burgess HM,Mohr I
Wed Aug 01 00:00:00 EDT 2018
IFI16 regulates HTLV-1 replication through promoting HTLV-1 RTI-induced innate immune responses.
FEBS letters
Yang B,Song D,Liu Y,Cui Y,Lu G,Di W,Xing H,Ma L,Guo Z,Guan Y,Wang H,Wang J
Tue May 01 00:00:00 EDT 2018
IFI16 regulates HTLV-1 replication through promoting HTLV-1 RTI-induced innate immune responses.
FEBS letters
Yang B,Song D,Liu Y,Cui Y,Lu G,Di W,Xing H,Ma L,Guo Z,Guan Y,Wang H,Wang J
Tue May 01 00:00:00 EDT 2018
IFI16 regulates HTLV-1 replication through promoting HTLV-1 RTI-induced innate immune responses.
FEBS letters
Yang B,Song D,Liu Y,Cui Y,Lu G,Di W,Xing H,Ma L,Guo Z,Guan Y,Wang H,Wang J
Tue May 01 00:00:00 EDT 2018
IFI16 regulates HTLV-1 replication through promoting HTLV-1 RTI-induced innate immune responses.
FEBS letters
Yang B,Song D,Liu Y,Cui Y,Lu G,Di W,Xing H,Ma L,Guo Z,Guan Y,Wang H,Wang J
Tue May 01 00:00:00 EDT 2018
Priming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts.
Nature communications
Torralba D,Baixauli F,Villarroya-Beltri C,Fernández-Delgado I,Latorre-Pellicer A,Acín-Pérez R,Martín-Cófreces NB,Jaso-Tamame ÁL,Iborra S,Jorge I,González-Aseguinolaza G,Garaude J,Vicente-Manzanares M,Enríquez JA,Mittelbrunn M,Sánchez-Madrid F
Mon Jul 09 00:00:00 EDT 2018
Priming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts.
Nature communications
Torralba D,Baixauli F,Villarroya-Beltri C,Fernández-Delgado I,Latorre-Pellicer A,Acín-Pérez R,Martín-Cófreces NB,Jaso-Tamame ÁL,Iborra S,Jorge I,González-Aseguinolaza G,Garaude J,Vicente-Manzanares M,Enríquez JA,Mittelbrunn M,Sánchez-Madrid F
Mon Jul 09 00:00:00 EDT 2018
Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D.
The Journal of biological chemistry
Motani K,Kosako H
Fri May 18 00:00:00 EDT 2018
Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D.
The Journal of biological chemistry
Motani K,Kosako H
Fri May 18 00:00:00 EDT 2018
Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D.
The Journal of biological chemistry
Motani K,Kosako H
Fri May 18 00:00:00 EDT 2018
Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D.
The Journal of biological chemistry
Motani K,Kosako H
Fri May 18 00:00:00 EDT 2018
Hepatitis B Virus Evasion From Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase Sensing in Human Hepatocytes.
Hepatology (Baltimore, Md.)
Verrier ER,Yim SA,Heydmann L,El Saghire H,Bach C,Turon-Lagot V,Mailly L,Durand SC,Lucifora J,Durantel D,Pessaux P,Manel N,Hirsch I,Zeisel MB,Pochet N,Schuster C,Baumert TF
Thu Nov 01 00:00:00 EDT 2018
A proteomics landscape of circadian clock in mouse liver.
Nature communications
Wang Y,Song L,Liu M,Ge R,Zhou Q,Liu W,Li R,Qie J,Zhen B,Wang Y,He F,Qin J,Ding C
Thu Apr 19 00:00:00 EDT 2018
A proteomics landscape of circadian clock in mouse liver.
Nature communications
Wang Y,Song L,Liu M,Ge R,Zhou Q,Liu W,Li R,Qie J,Zhen B,Wang Y,He F,Qin J,Ding C
Thu Apr 19 00:00:00 EDT 2018
STING positively regulates human ORMDL3 expression through TBK1-IRF3-STAT6 complex mediation.
Experimental cell research
Cao Q,Juan CX,Zhang DQ,He J,Cao YZ,Pasha AB,Wang JY,Qi HX,Li S,Jin R,Zhou GP
Sat Sep 15 00:00:00 EDT 2018
Expression of STING Is Increased in Liver Tissues From Patients With NAFLD and Promotes Macrophage-Mediated Hepatic Inflammation and Fibrosis in Mice.
Gastroenterology
Luo X,Li H,Ma L,Zhou J,Guo X,Woo SL,Pei Y,Knight LR,Deveau M,Chen Y,Qian X,Xiao X,Li Q,Chen X,Huo Y,McDaniel K,Francis H,Glaser S,Meng F,Alpini G,Wu C
Sat Dec 01 00:00:00 EST 2018
PUM1 is a biphasic negative regulator of innate immunity genes by suppressing LGP2.
Proceedings of the National Academy of Sciences of the United States of America
Liu Y,Qu L,Liu Y,Roizman B,Zhou GG
Tue Aug 15 00:00:00 EDT 2017
PUM1 is a biphasic negative regulator of innate immunity genes by suppressing LGP2.
Proceedings of the National Academy of Sciences of the United States of America
Liu Y,Qu L,Liu Y,Roizman B,Zhou GG
Tue Aug 15 00:00:00 EDT 2017
HTLV-1 Tax impairs K63-linked ubiquitination of STING to evade host innate immunity.
Virus research
Wang J,Yang S,Liu L,Wang H,Yang B
Wed Mar 15 00:00:00 EDT 2017
HTLV-1 Tax impairs K63-linked ubiquitination of STING to evade host innate immunity.
Virus research
Wang J,Yang S,Liu L,Wang H,Yang B
Wed Mar 15 00:00:00 EDT 2017
Ku70 Senses HTLV-1 DNA and Modulates HTLV-1 Replication.
Journal of immunology (Baltimore, Md. : 1950)
Wang J,Kang L,Song D,Liu L,Yang S,Ma L,Guo Z,Ding H,Wang H,Yang B
Sun Oct 01 00:00:00 EDT 2017
Ku70 Senses HTLV-1 DNA and Modulates HTLV-1 Replication.
Journal of immunology (Baltimore, Md. : 1950)
Wang J,Kang L,Song D,Liu L,Yang S,Ma L,Guo Z,Ding H,Wang H,Yang B
Sun Oct 01 00:00:00 EDT 2017
MITA modulated autophagy flux promotes cell death in breast cancer cells.
Cellular signalling
Bhatelia K,Singh K,Prajapati P,Sripada L,Roy M,Singh R
Sat Jul 01 00:00:00 EDT 2017
MITA modulated autophagy flux promotes cell death in breast cancer cells.
Cellular signalling
Bhatelia K,Singh K,Prajapati P,Sripada L,Roy M,Singh R
Sat Jul 01 00:00:00 EDT 2017
Indirubin, a bisindole alkaloid from Isatis indigotica, reduces H1N1 susceptibility in stressed mice by regulating MAVS signaling.
Oncotarget
Jie C,Luo Z,Chen H,Wang M,Yan C,Mao ZF,Xiao GK,Kurihara H,Li YF,He RR
Fri Dec 01 00:00:00 EST 2017
Indirubin, a bisindole alkaloid from Isatis indigotica, reduces H1N1 susceptibility in stressed mice by regulating MAVS signaling.
Oncotarget
Jie C,Luo Z,Chen H,Wang M,Yan C,Mao ZF,Xiao GK,Kurihara H,Li YF,He RR
Fri Dec 01 00:00:00 EST 2017
Decreased expression of STING predicts poor prognosis in patients with gastric cancer.
Scientific reports
Song S,Peng P,Tang Z,Zhao J,Wu W,Li H,Shao M,Li L,Yang C,Duan F,Zhang M,Zhang J,Wu H,Li C,Wang X,Wang H,Ruan Y,Gu J
Wed Feb 08 00:00:00 EST 2017
Decreased expression of STING predicts poor prognosis in patients with gastric cancer.
Scientific reports
Song S,Peng P,Tang Z,Zhao J,Wu W,Li H,Shao M,Li L,Yang C,Duan F,Zhang M,Zhang J,Wu H,Li C,Wang X,Wang H,Ruan Y,Gu J
Wed Feb 08 00:00:00 EST 2017
The RAB2B-GARIL5 Complex Promotes Cytosolic DNA-Induced Innate Immune Responses.
Cell reports
Takahama M,Fukuda M,Ohbayashi N,Kozaki T,Misawa T,Okamoto T,Matsuura Y,Akira S,Saitoh T
Tue Sep 19 00:00:00 EDT 2017
The RAB2B-GARIL5 Complex Promotes Cytosolic DNA-Induced Innate Immune Responses.
Cell reports
Takahama M,Fukuda M,Ohbayashi N,Kozaki T,Misawa T,Okamoto T,Matsuura Y,Akira S,Saitoh T
Tue Sep 19 00:00:00 EDT 2017
The RAB2B-GARIL5 Complex Promotes Cytosolic DNA-Induced Innate Immune Responses.
Cell reports
Takahama M,Fukuda M,Ohbayashi N,Kozaki T,Misawa T,Okamoto T,Matsuura Y,Akira S,Saitoh T
Tue Sep 19 00:00:00 EDT 2017
The RAB2B-GARIL5 Complex Promotes Cytosolic DNA-Induced Innate Immune Responses.
Cell reports
Takahama M,Fukuda M,Ohbayashi N,Kozaki T,Misawa T,Okamoto T,Matsuura Y,Akira S,Saitoh T
Tue Sep 19 00:00:00 EDT 2017
TRIM29 promotes DNA virus infections by inhibiting innate immune response.
Nature communications
Xing J,Zhang A,Zhang H,Wang J,Li XC,Zeng MS,Zhang Z
Mon Oct 16 00:00:00 EDT 2017
TRIM29 promotes DNA virus infections by inhibiting innate immune response.
Nature communications
Xing J,Zhang A,Zhang H,Wang J,Li XC,Zeng MS,Zhang Z
Mon Oct 16 00:00:00 EDT 2017
The Central Role of IFI204 in IFN-β Release and Autophagy Activation during Mycobacterium bovis Infection.
Frontiers in cellular and infection microbiology
Chunfa L,Xin S,Qiang L,Sreevatsan S,Yang L,Zhao D,Zhou X
Wed Dec 27 00:00:00 EST 2017
The Central Role of IFI204 in IFN-β Release and Autophagy Activation during Mycobacterium bovis Infection.
Frontiers in cellular and infection microbiology
Chunfa L,Xin S,Qiang L,Sreevatsan S,Yang L,Zhao D,Zhou X
Wed Dec 27 00:00:00 EST 2017
AIM2 inhibits autophagy and IFN-β production during M. bovis infection.
Oncotarget
Liu C,Yue R,Yang Y,Cui Y,Yang L,Zhao D,Zhou X
Tue Jul 26 00:00:00 EDT 2016
Activation of STING requires palmitoylation at the Golgi.
Nature communications
Mukai K,Konno H,Akiba T,Uemura T,Waguri S,Kobayashi T,Barber GN,Arai H,Taguchi T
Tue Jun 21 00:00:00 EDT 2016
Activation of STING requires palmitoylation at the Golgi.
Nature communications
Mukai K,Konno H,Akiba T,Uemura T,Waguri S,Kobayashi T,Barber GN,Arai H,Taguchi T
Tue Jun 21 00:00:00 EDT 2016
Hepatitis B virus polymerase disrupts K63-linked ubiquitination of STING to block innate cytosolic DNA-sensing pathways.
Journal of virology
Liu Y,Li J,Chen J,Li Y,Wang W,Du X,Song W,Zhang W,Lin L,Yuan Z
Sun Feb 01 00:00:00 EST 2015
Hepatitis B virus polymerase disrupts K63-linked ubiquitination of STING to block innate cytosolic DNA-sensing pathways.
Journal of virology
Liu Y,Li J,Chen J,Li Y,Wang W,Du X,Song W,Zhang W,Lin L,Yuan Z
Sun Feb 01 00:00:00 EST 2015
Hepatitis B virus polymerase disrupts K63-linked ubiquitination of STING to block innate cytosolic DNA-sensing pathways.
Journal of virology
Liu Y,Li J,Chen J,Li Y,Wang W,Du X,Song W,Zhang W,Lin L,Yuan Z
Sun Feb 01 00:00:00 EST 2015
Hepatitis B virus polymerase disrupts K63-linked ubiquitination of STING to block innate cytosolic DNA-sensing pathways.
Journal of virology
Liu Y,Li J,Chen J,Li Y,Wang W,Du X,Song W,Zhang W,Lin L,Yuan Z
Sun Feb 01 00:00:00 EST 2015
Antiviral signaling protein MITA acts as a tumor suppressor in breast cancer by regulating NF-κB induced cell death.
Biochimica et biophysica acta
Bhatelia K,Singh A,Tomar D,Singh K,Sripada L,Chagtoo M,Prajapati P,Singh R,Godbole MM,Singh R
Sat Feb 01 00:00:00 EST 2014
Antiviral signaling protein MITA acts as a tumor suppressor in breast cancer by regulating NF-κB induced cell death.
Biochimica et biophysica acta
Bhatelia K,Singh A,Tomar D,Singh K,Sripada L,Chagtoo M,Prajapati P,Singh R,Godbole MM,Singh R
Sat Feb 01 00:00:00 EST 2014
NET23/STING promotes chromatin compaction from the nuclear envelope.
PloS one
Malik P,Zuleger N,de las Heras JI,Saiz-Ros N,Makarov AA,Lazou V,Meinke P,Waterfall M,Kelly DA,Schirmer EC
Mon Dec 21 00:00:00 EST 2015
NET23/STING promotes chromatin compaction from the nuclear envelope.
PloS one
Malik P,Zuleger N,de las Heras JI,Saiz-Ros N,Makarov AA,Lazou V,Meinke P,Waterfall M,Kelly DA,Schirmer EC
Mon Dec 21 00:00:00 EST 2015
NET23/STING promotes chromatin compaction from the nuclear envelope.
PloS one
Malik P,Zuleger N,de las Heras JI,Saiz-Ros N,Makarov AA,Lazou V,Meinke P,Waterfall M,Kelly DA,Schirmer EC
Mon Dec 21 00:00:00 EST 2015
NET23/STING promotes chromatin compaction from the nuclear envelope.
PloS one
Malik P,Zuleger N,de las Heras JI,Saiz-Ros N,Makarov AA,Lazou V,Meinke P,Waterfall M,Kelly DA,Schirmer EC
Mon Dec 21 00:00:00 EST 2015
