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TMPRSS2 Antibody (PA5-117279) in IHC (P)
Immunohistochemistry analysis of TMPRSS2 in paraffin-embedded human prostate. Samples was treated with Citrate buffer (pH 6, 15 min) for antigen retrieval and incubated in TMPRSS2 polyclonal antibody (Product # PA5-117279) using a dilution of 1:500.
Product Details
PA5-117279
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human TMPRSS2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.01 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901909
Product Specific Information
Centrifuge briefly prior to opening.
Target Information
TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 3.4.219; epitheliasin; FLJ41954; MGC6821; Serine protease 10; TMPS2; Transmembrane protease serine 2
Gene Aliases: PP9284; PRSS10; TMPRSS2
UniProt ID: (Human) O15393
Entrez Gene ID: (Human) 7113
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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