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TMPRSS2 Antibody (PA5-143838) in ICC/IF
Immunofluorescent analysis of TMPRSS2 in 4% paraformaldehyde-fixed A549 cells. Samples were incubated in TMPRSS2 Polyclonal antibody (Product # PA5-143838) using a dilution of 20 µg/mL followed by goat anti-rabbit IgG secondary antibody at a 1:500 dilution (green) and DAPI staining (blue).
Product Details
PA5-143838
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A peptide corresponding to 12 amino acids near the carboxyl terminus of human TMPRSS2. The immunogen is located within the last 50 amino acids of TMPRSS2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3075052
Target Information
TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 3.4.219; Epitheliasin; FLJ41954; MGC6821; Plasmic transmembrane protein X; Serine protease 10; TMPS2; Transmembrane protease serine 2
Gene Aliases: D16Ertd61e; PP9284; PRSS10; TMPRSS2
UniProt ID: (Human) O15393, (Mouse) Q9JIQ8
Entrez Gene ID: (Human) 7113, (Mouse) 50528, (Rat) 156435
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