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Product Details
PA5-18847
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (TDWIYRQMRADG) corresponding to the internal amino acids of TMPRSS2
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_10977438
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 3.4.219; Epitheliasin; FLJ41954; MGC6821; Plasmic transmembrane protein X; Serine protease 10; TMPS2; Transmembrane protease serine 2
Gene Aliases: D16Ertd61e; PP9284; PRSS10; TMPRSS2
UniProt ID: (Human) O15393, (Mouse) Q9JIQ8
Entrez Gene ID: (Human) 7113, (Mouse) 50528, (Rat) 156435
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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