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Product Details
PA5-96019
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 140-400 of human TMPRSS2.
Conjugate
Form
Liquid
Concentration
1.02 mg/mL
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2807821
Product Specific Information
Immunogen sequence: GLLWKFMGSK CSNSGIECDS SGTCINPSNW CDGVSHCPGG EDENRCVRLY GPNFILQVYS SQRKSWHPVC QDDWNENYGR AACRDMGYKN NFYSSQGIVD DSGSTSFMKL NTSAGNVDIY KKLYHSDACS SKAVVSLRCI ACGVNLNSSR QSRIVGGESA LPGAWPWQVS LHVQNVHVCG GSIITPEWIV TAAHCVEKPL NNPWHWTAFA GILRQSFMFY GAGYQVEKVI SHPNYDSKTK NNDIALMKLQ KPLTFNDLVK P; Positive Samples: 22Rv1; Cellular Location: Cell membrane, Single-pass type II membrane protein
Target Information
TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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