Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: FMGSKCSNSG IECDSSGTCI NPSNWCDGVS HCPGGEDENR CVRLYGPNFI LQVYSSQRKS WHPVCQDDWN ENYGRAACRD MGYKNNFYSS QGIVDDSGST SFMKLNTSAG NVDIYKKLYH SDACSSKAVV SLRCIACGVN LNSSRQSRIV GGESALPGAW PWQVSLHVQN VHVCGGSIIT PEWIVTAAHC VEKPLNNPWH WTAFAGILRQ SFMFYGAGYQ VEKVISHPNY DSKTKNNDIA LMKLQKPLTF NDLVKPVCLP NPGMMLQPEQ LCWISGWGAT EEKGKTSEVL NAAKVLLIET QRCNSRYVYD NLITPAMICA GFLQGNVDSC QGDSGGPLVT SKNNIWWLIG DTSWGSGCAK AYRPGVYGNV MVFTDWIYRQ MRADG
TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.
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Protein Aliases: EC 3.4.219; epitheliasin; FLJ41954; MGC6821; Serine protease 10; TMPS2; Transmembrane protease serine 2
Gene Aliases: PP9284; PRSS10; TMPRSS2
UniProt ID: (Human) O15393
Entrez Gene ID: (Human) 7113
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