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NeoBiotechnologies
TMPRSS2 (Transmembrane Serine Protease 2) Monoclonal Antibody (TMPRSS2/7410)
Product Details
7113-MSM1-P1
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
TMPRSS2/7410
Immunogen
Recombinant full-length human TMPRSS2 protein
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A/G
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive Control: colon Expressed strongly in small intestine. Also expressed in prostate stomach and salivary gland.
Cellular Location: Secreted. Cell Surface.
Target Information
TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 3.4.219; epitheliasin; FLJ41954; MGC6821; Serine protease 10; TMPS2; Transmembrane protease serine 2
Gene Aliases: PP9284; PRSS10; TMPRSS2
UniProt ID: (Human) O15393
Entrez Gene ID: (Human) 7113
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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