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TNFR2 Antibody (MA5-52371) in Flow
Flow cytometry analysis of mouse TNFR2(TNFRSF1B) expression on L929 cells. Samples were incubated with TNFR2 monoclonal antibody (Product # MA5-52371). The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Product Details
MA5-52371
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
112
Immunogen
Recombinant Mouse TNFR2/CD120b/TNFRSF1B protein (Val 23-Gly258)
Conjugate
Excitation/Emission Max
651/660 nm
View spectra
Form
Liquid
Concentration
100 µg/mL
Purification
Protein A
Storage buffer
PBS with 0.05% BSA
Contains
0.03% ProClin 300
Storage conditions
4° C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD120b; p75; p75 TNFR; p80 TNF-alpha receptor; sCD120b; soluble CD120b; soluble TNFR2; sTNF R2; sTNFR 2; sTNFR2; TNF receptor beta chain; TNF-R2; TNF-RII; TNFR; TNFR II; TNFR-II; Tumor necrosis factor receptor; Tumor necrosis factor receptor 2; Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor type II
Gene Aliases: CD120b; p75; TNF-alphaR2; TNF-R-II; TNF-R2; TNF-R75; TNFalpha-R2; TNFBR; Tnfr-1; Tnfr-2; Tnfr2; TNFR80; TNFRII; Tnfrsf1b
UniProt ID: (Mouse) P25119
Entrez Gene ID: (Mouse) 21938
inflammatory response
immune response
cell surface receptor signaling pathway
cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage
programmed cell death
tumor necrosis factor-mediated signaling pathway
negative regulation of inflammatory response
RNA destabilization
positive regulation of membrane protein ectodomain proteolysis
cellular response to lipopolysaccharide
extrinsic apoptotic signaling pathway
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