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Product Details
TA804824
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1H5
Immunogen
Full length human recombinant protein of human TNNC1 produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Troponin (Tn) is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments, and as a result of calcium-ion uptake by troponin-C, the elements of the muscle thin filament undergo a series of allosteric changes which allow the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac 3; cardiac troponin C; CMD1FF; CMD2A; CMH7; MGC116817; RCM1; slow twitch skeletal/cardiac muscle troponin C; TN-C; Tn1; Tni; TNN I3; TNNC 1; TNNI3; troponin C type 1 (slow); Troponin C, slow skeletal and cardiac muscles; troponin C1, slow; Troponin I cardiac; TroponinI
Gene Aliases: CMD1Z; CMH13; TN-C; TNC; TNNC; TNNC1
UniProt ID: (Human) P63316
Entrez Gene ID: (Human) 7134
diaphragm contraction
skeletal muscle contraction
regulation of muscle contraction
response to metal ion
transition between fast and slow fiber
muscle filament sliding
regulation of muscle filament sliding speed
regulation of ATPase activity
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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