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In Western blot, this antibody detects a band at ~46 kDa (predicted molecular weight 50.8 kDa.
For optimal results, primary antibody incubations should be performed at room temperature.
Suggested positive control: antigen standard for TNFRSF19 (transient overexpression lysate), T98G.
TROY can mediate activation of c-Jun and NF-kappa-B. May promote caspase-independent cell death. Isoform 2 and isoform 3 may act as decoy receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Toxicity and JNK inducer; TRADE; Tumor necrosis factor receptor superfamily member 19; tumor necrosis factor receptor superfamily, member 19
Gene Aliases: AL023044; AW123854; TAJ; TAJ-ALPHA; TNFRSF19; TRADE; TROY; UNQ1888/PRO4333
UniProt ID: (Human) Q9NS68, (Mouse) Q9JJH6
Entrez Gene ID: (Human) 55504, (Mouse) 29820
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