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Product Details
PA5-66322
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human TRPS1. Recombinant protein control fragment (Product #RP-107003).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2665079
Product Specific Information
Immunogen sequence: SPIEKYQYPLF GLPFVHNDFQ SEADWLRFWS KYKLSVPGNP HYLSHVPGLP NPCQNYVPYP TFNLPPHFSA VGSDNDIPLD LAIKHSRPGP
Highest antigen sequence identity to the following orthologs - mouse 99%, rat 99%.
Target Information
This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Tricho-rhino-phalangeal syndrome type I protein; trichorhinophalangeal syndrome I; Zinc finger protein GC79; Zinc finger transcription factor Trps1
Gene Aliases: GC79; LGCR; TRPS1
UniProt ID: (Human) Q9UHF7
Entrez Gene ID: (Human) 7227
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
DNA-binding transcription factor
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
transcription from RNA polymerase II promoter
NLS-bearing protein import into nucleus
heart development
organ morphogenesis
tissue development
regulation of chondrocyte differentiation
cell fate commitment
positive regulation of transcription from RNA polymerase II promoter
cell development
digestive tract development
anatomical structure formation involved in morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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