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NeoBiotechnologies
TRPS1 (Transcriptional repressor GATA binding 1) Recombinant Rabbit Monoclonal Antibody (TRPS1/8131R)
FIGURE: 1 / 2
TRPS1 (Transcriptional repressor GATA binding 1) Antibody (7227-RBM10-P0) in IHC (P)
IHC analysis of Formalin-fixed, paraffin-embedded human brain. Negative tissue control using TRPS1/8131R at 2 µg/mL in PBS for 30 min RT. HIER: Tris/EDTA, pH9.0, 45 min. 2 °: HRP-polymer, 30 min. DAB, 5 min.
Product Details
7227-RBM10-P0
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
TRPS1/8131R
Immunogen
Recombinant fragment (around aa900-1100) of human TRPS1 protein.
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4° C, do not freeze
Shipping conditions
Wet ice
Target Information
This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Tricho-rhino-phalangeal syndrome type I protein; trichorhinophalangeal syndrome I; Zinc finger protein GC79; Zinc finger transcription factor Trps1
Gene Aliases: GC79; LGCR; TRPS1
UniProt ID: (Human) Q9UHF7
Entrez Gene ID: (Human) 7227
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
DNA-binding transcription factor
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
transcription from RNA polymerase II promoter
NLS-bearing protein import into nucleus
heart development
organ morphogenesis
tissue development
regulation of chondrocyte differentiation
cell fate commitment
positive regulation of transcription from RNA polymerase II promoter
cell development
digestive tract development
anatomical structure formation involved in morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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