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Antibody detects endogenous levels of total TSEN54.
This gene encodes a subunit of the tRNA splicing endonuclease complex, which catalyzes the removal of introns from precursor tRNAs. The complex is also implicated in pre-mRNA 3-prime end processing. Mutations in this gene result in pontocerebellar hypoplasia type 2.[provided by RefSeq, Oct 2009].
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Protein Aliases: HsSEN54; likely ortholog of H. sapiens SEN54L; SEN54 homolog; tRNA-intron endonuclease Sen54; tRNA-splicing endonuclease subunit Sen54; TSEN54 tRNA splicing endonuclease subunit
Gene Aliases: 0610034P02Rik; PCH2A; PCH4; PCH5; SEN54; SEN54L; TSEN54
UniProt ID: (Human) Q7Z6J9, (Mouse) Q8C2A2
Entrez Gene ID: (Human) 283989, (Mouse) 76265
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