Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 1
Positive Samples: HeLa, MCF7, 293T, Mouse kidney, Rat kidney
Immunogen sequence: MEPEPEPAAV EVPAGRVLSA RELFAARSRS QKLPQRSHGP KDFLPDGSAA QAERLRRCRE ELWQLLAEQR VERLGSLVAA EWRPEEGFVE LKSPAGKFWQ TMGFSEQGRQ RLHPEEALYL LECGSIHLFH QDLPLSIQEA YQLLLTDHTV TFLQYQVFSH LKRLGYVVRR FQPSSVLSPY ERQLNLDASV QHLEDGDGKR KRSSSSPRSI NKKAKALDNS LQPKSLAASS PPPCSQPSQC PEEKPQESSP MKGPGGPFQL LGSLGPSPGP AREGVGCSWE SGRAENGVTG AGKRRWNFEQ
This gene encodes a subunit of the tRNA splicing endonuclease complex, which catalyzes the removal of introns from precursor tRNAs. The complex is also implicated in pre-mRNA 3-prime end processing. Mutations in this gene result in pontocerebellar hypoplasia type 2.[provided by RefSeq, Oct 2009].
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Protein Aliases: HsSEN54; likely ortholog of H. sapiens SEN54L; SEN54 homolog; tRNA splicing endonuclease 54 homolog; tRNA-intron endonuclease Sen54; tRNA-splicing endonuclease subunit Sen54; TSEN54 tRNA splicing endonuclease subunit
Gene Aliases: 0610034P02Rik; PCH2A; PCH4; PCH5; SEN54; SEN54L; TSEN54
UniProt ID: (Human) Q7Z6J9, (Mouse) Q8C2A2
Entrez Gene ID: (Human) 283989, (Rat) 690308, (Mouse) 76265
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