Proteintech

TTC35 Polyclonal Antibody

FIGURE: 1 / 10

TTC35 Antibody (25443-1-AP) in WB

Human placenta tissue were subjected to SDS PAGE followed by western blot with 25443-1-AP (TTC35 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

TTC35 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

25443-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 11 publications 11 publications

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TTC35 Fusion Protein Ag22196 (1-297 aa encoded by BC021667)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.51 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAKVSELYD VTWEEMRDKM RKWREENSRN SEQIVEVGEE LINEYASKLG DDIWIIYEQV MIAALDYGRD DLALFCLQEL RRQFPGSHRV KRLTGMRFEA MERYDDAIQL YDRILQEDPT NTAARKRKIA IRKAQGKNVE AIRELNEYLE QFVGDQEAWH ELAELYINEH DYAKAAFCLE ELMMTNPHNH LYCQQYAEVK YTQGGLENLE LSRKYFAQAL KLNNRNMRAL FGLYMSASHI ASNPKASAKT KKDNMKYASW AASQINRAYQ FAGRSKKETK YSLKAVEDML ETLQITQS (1-297 aa encoded by BC021667)

Target Information

The exact function of TTC35 remains unknown.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

A selectivity filter in the ER membrane protein complex limits protein misinsertion at the ER.

The Journal of cell biology

Pleiner T,Hazu M,Pinton Tomaleri G,Nguyen VN,Januszyk K,Voorhees RM

Mon Aug 07 00:00:00 EDT 2023

A specific EMC subunit supports Dengue virus infection by promoting virus membrane fusion essential for cytosolic genome delivery.

PLoS pathogens

Bagchi P,Speckhart K,Kennedy A,Tai AW,Tsai B

Fri Jul 01 00:00:00 EDT 2022

WNK kinases sense molecular crowding and rescue cell volume via phase separation.

Cell

Boyd-Shiwarski CR,Shiwarski DJ,Griffiths SE,Beacham RT,Norrell L,Morrison DE,Wang J,Mann J,Tennant W,Anderson EN,Franks J,Calderon M,Connolly KA,Cheema MU,Weaver CJ,Nkashama LJ,Weckerly CC,Querry KE,Pandey UB,Donnelly CJ,Sun D,Rodan AR,Subramanya AR

Wed Nov 23 00:00:00 EST 2022

ATP13A1 prevents ERAD of folding-competent mislocalized and misoriented proteins.

Molecular cell

McKenna MJ,Adams BM,Chu V,Paulo JA,Shao S

Thu Nov 17 00:00:00 EST 2022

Mechanism of an intramembrane chaperone for multipass membrane proteins.

Nature

Smalinskaitė L,Kim MK,Lewis AJO,Keenan RJ,Hegde RS

Tue Nov 01 00:00:00 EDT 2022

The endoplasmic reticulum membrane complex promotes proteostasis of GABA_A receptors.

iScience

Whittsette AL,Wang YJ,Mu TW

Fri Aug 19 00:00:00 EDT 2022

WNK1 is an assembly factor for the human ER membrane protein complex.

Molecular cell

Pleiner T,Hazu M,Tomaleri GP,Januszyk K,Oania RS,Sweredoski MJ,Moradian A,Guna A,Voorhees RM

Thu Jul 01 00:00:00 EDT 2021

Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.

eLife

Miller-Vedam LE,Bräuning B,Popova KD,Schirle Oakdale NT,Bonnar JL,Prabu JR,Boydston EA,Sevillano N,Shurtleff MJ,Stroud RM,Craik CS,Schulman BA,Frost A,Weissman JS

Wed Nov 25 00:00:00 EST 2020

The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis.

Journal of cell science

Volkmar N,Thezenas ML,Louie SM,Juszkiewicz S,Nomura DK,Hegde RS,Kessler BM,Christianson JC

Wed Jan 16 00:00:00 EST 2019

The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis.

Journal of cell science

Volkmar N,Thezenas ML,Louie SM,Juszkiewicz S,Nomura DK,Hegde RS,Kessler BM,Christianson JC

Wed Jan 16 00:00:00 EST 2019

The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins.

eLife

Ngo AM,Shurtleff MJ,Popova KD,Kulsuptrakul J,Weissman JS,Puschnik AS

Fri Sep 13 00:00:00 EDT 2019

EMC Is Required to Initiate Accurate Membrane Protein Topogenesis.

Cell

Chitwood PJ,Juszkiewicz S,Guna A,Shao S,Hegde RS

Thu Nov 29 00:00:00 EST 2018

EMC Is Required to Initiate Accurate Membrane Protein Topogenesis.

Cell

Chitwood PJ,Juszkiewicz S,Guna A,Shao S,Hegde RS

Thu Nov 29 00:00:00 EST 2018

SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome.

EMBO molecular medicine

Janer A,Prudent J,Paupe V,Fahiminiya S,Majewski J,Sgarioto N,Des Rosiers C,Forest A,Lin ZY,Gingras AC,Mitchell G,McBride HM,Shoubridge EA

Thu Sep 01 00:00:00 EDT 2016

SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome.

EMBO molecular medicine

Janer A,Prudent J,Paupe V,Fahiminiya S,Majewski J,Sgarioto N,Des Rosiers C,Forest A,Lin ZY,Gingras AC,Mitchell G,McBride HM,Shoubridge EA

Thu Sep 01 00:00:00 EDT 2016

Bioinformatics

Protein Aliases: ER membrane protein complex subunit 2; tetratricopeptide repeat domain 35; Tetratricopeptide repeat protein 35; TPR repeat protein 35

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Gene Aliases: 4921531G14Rik; AV060620; AW209495; EMC2; KIAA0103; RGD1310430; TTC35

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UniProt ID: (Human) Q15006, (Rat) B0BNG0, (Mouse) Q9CRD2

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Entrez Gene ID: (Human) 9694, (Rat) 362905, (Mouse) 66736

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Function(s)

molecular_function chaperone

Process(es)

biological_process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

TTC35 Polyclonal Antibody

TTC35 Antibody (25443-1-AP) in WB

Product Details

25443-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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