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Immunogen sequence: PWGPASIQVA LSRKSPYLPS AHRVSGLMMA NHTSISSLFE RTCRQYDKLR KREAFLEQFR KEDMFKDNFD EMDTSREIVQ QLIDEYHAAT RPDYISWGTQ E; Positive Samples: MCF-7, HeLa, Mouse brain, Mouse lung, Rat brain; Cellular Location: Cytoplasm, centrosome, cytoskeleton, microtubule organizing center
This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7.
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Protein Aliases: Gamma-1-tubulin; Gamma-tubulin complex component 1; GCP-1; Tubulin gamma-1 chain; tubulin, gamma 1; tubulin, gamma polypeptide
Gene Aliases: 1500010O08Rik; AI451582; AI503389; CDCBM4; GCP-1; TUBG; TUBG1; TUBGCP1
UniProt ID: (Human) P23258, (Mouse) P83887, (Rat) P83888
Entrez Gene ID: (Human) 7283, (Mouse) 103733, (Rat) 252921
Molecular Function: tubulin
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