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Antibody detects endogenous levels of total TWISTNB.
DNA-directed RNA polymerase I subunit RPA43 or Twist neighbor protein (Twistnb)belongs to the eukaryotic RPA43 RNA polymerase subunit family. It catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.Twistnb is the component of RNA polymerase I which synthesizes ribosomal RNA precursors. It is widely expressed in all fetal and adult tissues, with highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues. Twist genes are essential for embryonic development and are conserved from jellyfish to human.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA-directed RNA polymerase I subunit F; DNA-directed RNA polymerase I subunit RPA43; Twist neighbor protein
Gene Aliases: POLR1F; TWISTNB
UniProt ID: (Human) Q3B726
Entrez Gene ID: (Human) 221830
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