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Positive test controls include: U-251MG, 293T, HepG2, Mouse brain, Mouse heart, Mouse kidney. The target is usually found in the following locations: Endoplasmic reticulum lumen.
Immunogen sequence: NLEDEEEPKD EDFSPDGGYI PRILFLDPSG KVHPEIINEN GNPSYKYFYV SAEQVVQGMK EAQERLTGDA FRKKHLEDEL
TXNDC12 belongs to the thioredoxin superfamily. Members of this superfamily possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors.
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Protein Aliases: anterior gradient homolog 1; endoplasmic reticulum protein ERp19; Endoplasmic reticulum resident protein 18; Endoplasmic reticulum resident protein 19; endoplasmic reticulum thioredoxin superfamily member, 18 kDa; ER protein 18; ER protein 19; hTLP19; ortholog of endoplasmic reticulum thioredoxin superfamily member, 18 kDa TLP19; protein disulfide isomerase family A, member 16; thioredoxin domain containing 12 (endoplasmic reticulum); Thioredoxin domain-containing protein 12; Thioredoxin-like protein p19
Gene Aliases: 0610040B21Rik; AG1; AGR1; ERP16; ERP18; ERP19; hAG-1; hTLP19; PDIA16; RGD1305960; TLP19; TXNDC12; UNQ713/PRO1376
UniProt ID: (Human) O95881, (Mouse) Q9CQU0, (Rat) Q498E0
Entrez Gene ID: (Human) 51060, (Mouse) 66073, (Rat) 298370
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