Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: EVQLQTVIN NQSLWDEMLQ NKGLTVIDVY QAWCGPCRAM QPLFRKLKNE LNEDEILHFA VAEADNIVTL QPFRDKCEPV FLFSVNGKII EKIQGANAPL VNKKVINLID EERKIAAGEM ARPQYPEIPL VDSDSEVSEE SPCESVQELY SIAIIKPDAV ISKKVLEIKR KITKAGFIIE AEHKTVLTEE QVVNFYSRIA DQRDFEEFVS FMTSGLSYIL VVSQGSKHNP PSEETEPQTD TEPNERSEDQ PEVEAQVTPG MMKNKQDSLQ EYLERQHLAQ LCDIEEDAAN VAKFMDAFFP DFKKMKSMKL EKTLALLRPN LFHERKDDVL RIIKDEDFKI LEQRQVVLSE KEAQALCKEY ENEDY (7-370 aa encoded by BC036816)
This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3'-5' exonuclease NME8; epididymis secretory protein Li 99; NM23-H8; NME/NM23 family member 8; sperm-specific thioredoxin 2; Spermatid-specific thioredoxin-2; spermatid-specific thioredoxin-2 protein; Sptrx-2; thioredoxin domain containing 3 (spermatozoa); Thioredoxin domain-containing protein 3
Gene Aliases: 1700056P15Rik; CILD6; HEL-S-99; NM23-H8; NME8; Sptrx-2; SPTRX2; TXNDC3
UniProt ID: (Human) Q8N427, (Mouse) Q715T0
Entrez Gene ID: (Human) 51314, (Rat) 364729, (Mouse) 73412
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support