Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Sequence homology: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 93%; Sheep: 100%
This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.
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Protein Aliases: 5,6-dihydroxyindole-2-carboxylic acid oxidase; Brown locus protein; Catalase B; DHICA oxidase; Glycoprotein 75; iris stromal atrophy; Melanoma antigen gp75; MGC120175; MGC149362; RP11-3L8.1; TRP; TRY1; TRY4; TRYP1; Tyrosinase-related protein 1
Gene Aliases: b; b-PROTEIN; brown; CAS2; CATB; GP75; isa; OCA3; TRP; TRP-1; TRP1; TYRP; Tyrp-1; TYRP1; TYRRP
UniProt ID: (Human) P17643, (Mouse) P07147
Entrez Gene ID: (Human) 7306, (Mouse) 22178
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