Product References
Okadaic Acid-Induced Alzheimer's in Rat Brain: Phytochemical Cucurbitacin E Contributes to Memory Gain by Reducing TAU Protein Accumulation.
Omics : a journal of integrative biology
Yılmaz ŞG,Almasri S,Karabulut YY,Korkmaz M,Bucak Ö,Balcı SO
Published figure using Tau monoclonal antibody (Product # 13-6400) in Western Blot
Sun Jan 01 00:00:00 EST 2023
Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy.
Acta neuropathologica communications
Qi C,Hasegawa M,Takao M,Sakai M,Sasaki M,Mizutani M,Akagi A,Iwasaki Y,Miyahara H,Yoshida M,Scheres SHW,Goedert M
Published figure using Tau monoclonal antibody (Product # 13-6400) in Western Blot
Fri May 05 00:00:00 EDT 2023
An early proinflammatory transcriptional response to tau pathology is age-specific and foreshadows reduced tau burden.
Brain pathology (Zurich, Switzerland)
Rasmussen J,Ewing AD,Bodea LG,Bodea GO,Gearing M,Faulkner GJ
Published figure using Tau monoclonal antibody (Product # 13-6400) in Western Blot
Sun May 01 00:00:00 EDT 2022
ATase inhibition rescues age-associated proteotoxicity of the secretory pathway.
Communications biology
Murie M,Peng Y,Rigby MJ,Dieterich IA,Farrugia MA,Endresen A,Bhattacharyya A,Puglielli L
Published figure using Tau monoclonal antibody (Product # 13-6400) in Western Blot
Fri Feb 25 00:00:00 EST 2022
ATase inhibition rescues age-associated proteotoxicity of the secretory pathway.
Communications biology
Murie M,Peng Y,Rigby MJ,Dieterich IA,Farrugia MA,Endresen A,Bhattacharyya A,Puglielli L
Published figure using Tau monoclonal antibody (Product # 13-6400) in Western Blot
Fri Feb 25 00:00:00 EST 2022
Central role for p62/SQSTM1 in the elimination of toxic tau species in a mouse model of tauopathy.
Aging cell
Ono M,Komatsu M,Ji B,Takado Y,Shimojo M,Minamihisamatsu T,Warabi E,Yanagawa T,Matsumoto G,Aoki I,Kanaan NM,Suhara T,Sahara N,Higuchi M
Published figure using Tau monoclonal antibody (Product # 13-6400) in Immunohistochemistry
Fri Jul 01 00:00:00 EDT 2022
Blocking Site-Specific Cleavage of Human Tau Delays Progression of Disease-Related Phenotypes in Genetically Matched Tau-Transgenic Mice Modeling Frontotemporal Dementia.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Steuer EL,Kemper LJ,Hlynialuk CJW,Leinonen-Wright K,Montonye ML,Lapcinski IP,Forster CL,Ashe KH,Liu P
13-6400 was used in Western Blotting to demonstrate that htau transgene expression occurs primarily in the forebrain at similar levels in rT2 and rT3 mice.
Wed Jun 08 00:00:00 EDT 2022
Spatially resolved transcriptomics reveals genes associated with the vulnerability of middle temporal gyrus in Alzheimer's disease.
Acta neuropathologica communications
Chen S,Chang Y,Li L,Acosta D,Li Y,Guo Q,Wang C,Turkes E,Morrison C,Julian D,Hester ME,Scharre DW,Santiskulvong C,Song SX,Plummer JT,Serrano GE,Beach TG,Duff KE,Ma Q,Fu H
13-6400 was used in Immunohistochemistry-immunofluorescence to utilize the 10 Visium platform to define the spatial transcriptomic profile in both AD and control (CT) MTG.
Wed Dec 21 00:00:00 EST 2022
Dephosphorylation Passivates the Seeding Activity of Oligomeric Tau Derived From Alzheimer's Brain.
Frontiers in molecular neuroscience
Wu R,Li L,Shi R,Zhou Y,Jin N,Gu J,Tung YC,Liu F,Chu D
Published figure using Tau monoclonal antibody (Product # 13-6400) in Western Blot
Tue Jun 01 00:00:00 EDT 2021
α- Linolenic acid modulates phagocytosis and endosomal pathways of extracellular Tau in microglia.
Cell adhesion & migration
Desale SE,Chinnathambi S
13-6400 was used in Immunocytochemistry-immunoflourescence to suggest that microglia could be influenced to reduce extracellular Tau seed with dietary fatty acids.
Wed Dec 01 00:00:00 EST 2021
α- Linolenic acid modulates phagocytosis and endosomal pathways of extracellular Tau in microglia.
Cell adhesion & migration
Desale SE,Chinnathambi S
13-6400 was used in Immunocytochemistry-immunoflourescence to suggest that microglia could be influenced to reduce extracellular Tau seed with dietary fatty acids.
Wed Dec 01 00:00:00 EST 2021
UBE4B, a microRNA-9 target gene, promotes autophagy-mediated Tau degradation.
Nature communications
Subramanian M,Hyeon SJ,Das T,Suh YS,Kim YK,Lee JS,Song EJ,Ryu H,Yu K
13-6400 was used in Western Blot to demonstrate that UBE4B, a miR-9 target gene, promotes autophagy-mediated Tau degradation together with STUB1, and is thus an innovative therapeutic approach for AD.
Wed Jun 02 00:00:00 EDT 2021
UBE4B, a microRNA-9 target gene, promotes autophagy-mediated Tau degradation.
Nature communications
Subramanian M,Hyeon SJ,Das T,Suh YS,Kim YK,Lee JS,Song EJ,Ryu H,Yu K
13-6400 was used in Western Blot to demonstrate that UBE4B, a miR-9 target gene, promotes autophagy-mediated Tau degradation together with STUB1, and is thus an innovative therapeutic approach for AD.
Wed Jun 02 00:00:00 EDT 2021
5-hydroxymethylcytosine is dynamically regulated during forebrain organoid development and aberrantly altered in Alzheimer's disease.
Cell reports
Kuehner JN,Chen J,Bruggeman EC,Wang F,Li Y,Xu C,McEachin ZT,Li Z,Chen L,Hales CM,Wen Z,Yang J,Yao B
13-6400 was used in Immunohistochemistry-immunofluorescence to generate 5hmC and transcriptome profiles encompassing several developmental time points of healthy forebrain organoids and organoids derived from several familial Alzheimer's disease (AD) patients.
Tue Apr 27 00:00:00 EDT 2021
Phagocytosis of full-length Tau oligomers by Actin-remodeling of activated microglia.
Journal of neuroinflammation
Das R,Balmik AA,Chinnathambi S
Published figure using Tau monoclonal antibody (Product # 13-6400) in Immunocytochemistry
Wed Jan 08 00:00:00 EST 2020
Basic Limonoid modulates Chaperone-mediated Proteostasis and dissolve Tau fibrils.
Scientific reports
Gorantla NV,Das R,Chidambaram H,Dubey T,Mulani FA,Thulasiram HV,Chinnathambi S
Published figure using Tau monoclonal antibody (Product # 13-6400) in Immunocytochemistry
Wed Mar 04 00:00:00 EST 2020
Asparagine residue 368 is involved in Alzheimer's disease tau strain-specific aggregation.
The Journal of biological chemistry
Shimonaka S,Matsumoto SE,Elahi M,Ishiguro K,Hasegawa M,Hattori N,Motoi Y
13-6400 was used in Western Blot to suggest that 353-368 aa is a novel aggregation-responsible sequence other than PHF6 and PHF6*, and within this sequence, the Asn-368 residue plays a role in strain-specific tau aggregation in different tauopathies.
Fri Oct 09 00:00:00 EDT 2020
Melatonin Reduces GSK3β-Mediated Tau Phosphorylation, Enhances Nrf2 Nuclear Translocation and Anti-Inflammation.
ASN neuro
Das R,Balmik AA,Chinnathambi S
13-6400 was used in Immunocytochemistry-immunoflourescence to check the neuroprotective function of Melatonin by MTT and LDH assay, where Melatonin inhibited the Tau aggregates-mediated cytotoxicity and membrane leakage in Neuro2A cells.
Wed Oct 06 00:00:00 EDT 2021
Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau.
Molecular psychiatry
Audrain M,Haure-Mirande JV,Wang M,Kim SH,Fanutza T,Chakrabarty P,Fraser P,St George-Hyslop PH,Golde TE,Blitzer RD,Schadt EE,Zhang B,Ehrlich ME,Gandy S
13-6400 was used in Western Blotting to characterise in mice the effects of TYROBP deficiency on the phenotypic and pathological evolution of tauopathy.
Sun Sep 01 00:00:00 EDT 2019
Suppression of glioblastoma by a drug cocktail reprogramming tumor cells into neuronal like cells.
Scientific reports
Gao L,Huang S,Zhang H,Hua W,Xin S,Cheng L,Guan W,Yu Y,Mao Y,Pei G
13-6400 was used in Immunocytochemistry-immunoflourescence to study the use of a neuronal reprogramming drug cocktail to improve existing treatment for glioblastoma.
Tue Mar 05 00:00:00 EST 2019
Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors.
Science advances
Dominy SS,Lynch C,Ermini F,Benedyk M,Marczyk A,Konradi A,Nguyen M,Haditsch U,Raha D,Griffin C,Holsinger LJ,Arastu-Kapur S,Kaba S,Lee A,Ryder MI,Potempa B,Mydel P,Hellvard A,Adamowicz K,Hasturk H,Walker GD,Reynolds EC,Faull RLM,Curtis MA,Dragunow M,Potempa J
13-6400 was used in Western Blotting to study porphyromonas gingivalis in Alzheimer's disease brains.
Tue Jan 01 00:00:00 EST 2019
Relevance of Phosphorylation and Truncation of Tau to the Etiopathogenesis of Alzheimer's Disease.
Frontiers in aging neuroscience
Zhou Y,Shi J,Chu D,Hu W,Guan Z,Gong CX,Iqbal K,Liu F
13-6400 was used in Western Blotting to suggest that tau pathogenesis involves both hyperphosphorylation and dominantly N-terminal truncation of tau in AD.
Sat Apr 09 00:00:00 EDT 2022
Impacts of Acute Hypoxia on Alzheimer's Disease-Like Pathologies in APPswe/PS1dE9 Mice and Their Wild Type Littermates.
Frontiers in neuroscience
Zhang F,Zhong R,Qi H,Li S,Cheng C,Liu X,Liu Y,Le W
13-6400 was used in Western Blotting to suggest that acute hypoxia could induce Alzheimer's disease-like pathological damages in the brain of APPswe/PS1dE9 mice and wild type mice.
Thu Oct 01 00:00:00 EDT 2020
Both secreted and the cellular levels of BDNF attenuated due to tau hyperphosphorylation in primary cultures of cortical neurons.
Journal of chemical neuroanatomy
Atasoy İL,Dursun E,Gezen-Ak D,Metin-Armağan D,Öztürk M,Yılmazer S
136400 was used in immunocytochemistry to report the effects of okadaic acid-induced tau hyperphosphorylation on secreted and cellular levels of brain-derived neurotrophic factor in primary cortical neurons
Wed Mar 01 00:00:00 EST 2017
A Dual Pathogenic Mechanism Links Tau Acetylation to Sporadic Tauopathy.
Scientific reports
Trzeciakiewicz H,Tseng JH,Wander CM,Madden V,Tripathy A,Yuan CX,Cohen TJ
136400 was used in immunoprecipitation and western blot to study the mechanisms of pathogenesis via tau acetylation in Alzheimer's disease
Mon Mar 13 00:00:00 EDT 2017
Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tau.
Acta neuropathologica
Taniguchi-Watanabe S,Arai T,Kametani F,Nonaka T,Masuda-Suzukake M,Tarutani A,Murayama S,Saito Y,Arima K,Yoshida M,Akiyama H,Robinson A,Mann DMA,Iwatsubo T,Hasegawa M
13-6400 was used in immunohistochemistry and western blot to assess using the biochemical properties of tau to classify tauopathies
Mon Feb 01 00:00:00 EST 2016
Improved proteostasis in the secretory pathway rescues Alzheimer's disease in the mouse.
Brain : a journal of neurology
Peng Y,Kim MJ,Hullinger R,O'Riordan KJ,Burger C,Pehar M,Puglielli L
13-6400 was used in western blot to assess rescue of Alzheimer's disease in the mouse by improved proteostasis in the secretory pathway
Tue Mar 01 00:00:00 EST 2016
Globular Glial Mixed Four Repeat Tau and TDP-43 Proteinopathy with Motor Neuron Disease and Frontotemporal Dementia.
Brain pathology (Zurich, Switzerland)
Takeuchi R,Toyoshima Y,Tada M,Tanaka H,Shimizu H,Shiga A,Miura T,Aoki K,Aikawa A,Ishizawa S,Ikeuchi T,Nishizawa M,Kakita A,Takahashi H
13-6400 was used in western blot to report a case of glial mixed tau and TDP-43 proteinopathies in a Japanese patient.
Fri Jan 01 00:00:00 EST 2016
Mutations in LRRK2 impair NF-κB pathway in iPSC-derived neurons.
Journal of neuroinflammation
López de Maturana R,Lang V,Zubiarrain A,Sousa A,Vázquez N,Gorostidi A,Águila J,López de Munain A,Rodríguez M,Sánchez-Pernaute R
136400 was used in immunocytochemistry and western blot to discuss the contribution of leucine-rich repeat kinase 2 mutations to Parkinson's disease
Fri Nov 18 00:00:00 EST 2016
Mutations in LRRK2 impair NF-κB pathway in iPSC-derived neurons.
Journal of neuroinflammation
López de Maturana R,Lang V,Zubiarrain A,Sousa A,Vázquez N,Gorostidi A,Águila J,López de Munain A,Rodríguez M,Sánchez-Pernaute R
136400 was used in immunocytochemistry and western blot to discuss the contribution of leucine-rich repeat kinase 2 mutations to Parkinson's disease
Fri Nov 18 00:00:00 EST 2016
Conserved Lysine Acetylation within the Microtubule-Binding Domain Regulates MAP2/Tau Family Members.
PloS one
Hwang AW,Trzeciakiewicz H,Friedmann D,Yuan CX,Marmorstein R,Lee VM,Cohen TJ
136400 was used in western blot to show that the tau family members MAP2 and MAP4 are subject to reversible acetylation
Mon Jul 03 00:00:00 EDT 2017
Different pathways of molecular pathophysiology underlie cognitive and motor tauopathy phenotypes in transgenic models for Alzheimer's disease and frontotemporal lobar degeneration.
Cellular and molecular life sciences : CMLS
Melis V,Zabke C,Stamer K,Magbagbeolu M,Schwab K,Marschall P,Veh RW,Bachmann S,Deiana S,Moreau PH,Davidson K,Harrington KA,Rickard JE,Horsley D,Garman R,Mazurkiewicz M,Niewiadomska G,Wischik CM,Harrington CR,Riedel G,Theuring F
Published figure using Tau monoclonal antibody (Product # 13-6400) in Western Blot
Mon Jun 01 00:00:00 EDT 2015
Different pathways of molecular pathophysiology underlie cognitive and motor tauopathy phenotypes in transgenic models for Alzheimer's disease and frontotemporal lobar degeneration.
Cellular and molecular life sciences : CMLS
Melis V,Zabke C,Stamer K,Magbagbeolu M,Schwab K,Marschall P,Veh RW,Bachmann S,Deiana S,Moreau PH,Davidson K,Harrington KA,Rickard JE,Horsley D,Garman R,Mazurkiewicz M,Niewiadomska G,Wischik CM,Harrington CR,Riedel G,Theuring F
Published figure using Tau monoclonal antibody (Product # 13-6400) in Western Blot
Mon Jun 01 00:00:00 EDT 2015
Tamoxifen inhibits CDK5 kinase activity by interacting with p35/p25 and modulates the pattern of tau phosphorylation.
Chemistry & biology
Corbel C,Zhang B,Le Parc A,Baratte B,Colas P,Couturier C,Kosik KS,Landrieu I,Le Tilly V,Bach S
13-6400 was used in western blot to identify small-molecules that inhibit the interaction between CDK5 and p25
Thu Apr 23 00:00:00 EDT 2015
Total body 100-mGy X-irradiation does not induce Alzheimer's disease-like pathogenesis or memory impairment in mice.
Journal of radiation research
Wang B,Tanaka K,Ji B,Ono M,Fang Y,Ninomiya Y,Maruyama K,Izumi-Nakajima N,Begum N,Higuchi M,Fujimori A,Uehara Y,Nakajima T,Suhara T,Ono T,Nenoi M
Wed Jan 01 00:00:00 EST 2014
Dissociation of tau toxicity and phosphorylation: role of GSK-3beta, MARK and Cdk5 in a Drosophila model.
Human molecular genetics
Chatterjee S,Sang TK,Lawless GM,Jackson GR
13-6400 was used in Western Blot to suggest that, in addition to tau phosphorylation, microtubule binding plays a crucial role in the regulation of tau toxicity when misexpressed.
Thu Jan 01 00:00:00 EST 2009
Abeta and tau form soluble complexes that may promote self aggregation of both into the insoluble forms observed in Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America
Guo JP,Arai T,Miklossy J,McGeer PL
Tue Feb 07 00:00:00 EST 2006
Abeta and tau form soluble complexes that may promote self aggregation of both into the insoluble forms observed in Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America
Guo JP,Arai T,Miklossy J,McGeer PL
Tue Feb 07 00:00:00 EST 2006
Abeta and tau form soluble complexes that may promote self aggregation of both into the insoluble forms observed in Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America
Guo JP,Arai T,Miklossy J,McGeer PL
Tue Feb 07 00:00:00 EST 2006
Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Mendes SW,Henkemeyer M,Liebl DJ
Wed Jan 18 00:00:00 EST 2006
Neurodegeneration in heterozygous Niemann-Pick type C1 (NPC1) mouse: implication of heterozygous NPC1 mutations being a risk for tauopathy.
The Journal of biological chemistry
Yu W,Ko M,Yanagisawa K,Michikawa M
Fri Jul 22 00:00:00 EDT 2005
Fyn phosphorylates human MAP-2c on tyrosine 67.
The Journal of biological chemistry
Zamora-Leon SP,Bresnick A,Backer JM,Shafit-Zagardo B
Fri Jan 21 00:00:00 EST 2005
Proteolysis of non-phosphorylated and phosphorylated tau by thrombin.
The Journal of biological chemistry
Arai T,Guo JP,McGeer PL
Fri Feb 18 00:00:00 EST 2005
Proteolysis of non-phosphorylated and phosphorylated tau by thrombin.
The Journal of biological chemistry
Arai T,Guo JP,McGeer PL
Fri Feb 18 00:00:00 EST 2005
Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology.
The Journal of clinical investigation
Rissman RA,Poon WW,Blurton-Jones M,Oddo S,Torp R,Vitek MP,LaFerla FM,Rohn TT,Cotman CW
Thu Jul 01 00:00:00 EDT 2004
Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology.
The Journal of clinical investigation
Rissman RA,Poon WW,Blurton-Jones M,Oddo S,Torp R,Vitek MP,LaFerla FM,Rohn TT,Cotman CW
Thu Jul 01 00:00:00 EDT 2004
Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology.
The Journal of clinical investigation
Rissman RA,Poon WW,Blurton-Jones M,Oddo S,Torp R,Vitek MP,LaFerla FM,Rohn TT,Cotman CW
Thu Jul 01 00:00:00 EDT 2004
Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology.
The Journal of clinical investigation
Rissman RA,Poon WW,Blurton-Jones M,Oddo S,Torp R,Vitek MP,LaFerla FM,Rohn TT,Cotman CW
Thu Jul 01 00:00:00 EDT 2004
Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17.
Proceedings of the National Academy of Sciences of the United States of America
Clark LN,Poorkaj P,Wszolek Z,Geschwind DH,Nasreddine ZS,Miller B,Li D,Payami H,Awert F,Markopoulou K,Andreadis A,D'Souza I,Lee VM,Reed L,Trojanowski JQ,Zhukareva V,Bird T,Schellenberg G,Wilhelmsen KC
Tue Oct 27 00:00:00 EST 1998
Cognitive, neuroimaging, and pathological studies in a patient with Pick's disease.
Annals of neurology
Lieberman AP,Trojanowski JQ,Lee VM,Balin BJ,Ding XS,Greenberg J,Morrison D,Reivich M,Grossman M
Sun Feb 01 00:00:00 EST 1998
Cognitive, neuroimaging, and pathological studies in a patient with Pick's disease.
Annals of neurology
Lieberman AP,Trojanowski JQ,Lee VM,Balin BJ,Ding XS,Greenberg J,Morrison D,Reivich M,Grossman M
Sun Feb 01 00:00:00 EST 1998
The neuropathology of a chromosome 17-linked autosomal dominant parkinsonism and dementia ("pallido-ponto-nigral degeneration").
Journal of neuropathology and experimental neurology
Reed LA,Schmidt ML,Wszolek ZK,Balin BJ,Soontornniyomkij V,Lee VM,Trojanowski JQ,Schelper RL
Mon Jun 01 00:00:00 EDT 1998
