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FIGURE: 1 / 1
Thrombomodulin Antibody (PA5-47550) in ICC/IF
Immunocytochemical analysis of Thrombomodulin/BDCA-3 was detected in immersion fixed bEnd.3 mouse endothelioma cell line using Goat Anti-mouse Thrombomodulin/BDCA-3 Antigen Affinity-purified Polyclonal Antibody (Product # PA5-47550) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the 493-conjugated Anti-Goat IgG Secondary Antibody (gree and counterstained with DAPI (blue). Specific sta... View More
Product Details
PA5-47550
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Thrombomodulin/BDCA-3 Leu17-Ser517
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609393
Product Specific Information
In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human Thrombomodulin is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112. Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells. Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BDCA-3; CD141; DC141; Fetomodulin; sCD141; snoRNA MBII-339; soluble CD141; Thrombomodulin; TM
Gene Aliases: AI385582; CD141; Thbd; TM
UniProt ID: (Mouse) P15306
Entrez Gene ID: (Mouse) 21824
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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