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Bethyl Laboratories
Thrombomodulin Recombinant Rabbit Monoclonal Antibody (BLR253L)
FIGURE: 1 / 7
Thrombomodulin Antibody (A700-253) in ICC/IF
Detection of human Thrombomodulin by immunocytochemistry. Sample: FFPE section of human SW954 cells. Antibody: Rabbit anti-Thrombomodulin recombinant monoclonal antibody [BLR253L) (A700-253). Secondary: HRP-conjugated goat anti-rabbit IgG (A120-501P).
Product Details
A700-253
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
BLR253L
Immunogen
Recombinant protein representing the extracellular domain of Human Thrombomodulin (residues 17-515).
Conjugate
Form
Liquid
Concentration
500 µg/mL
Purification
purified
Storage buffer
BBS, pH 8.2, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunohistochemistry: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112. Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells. Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BDCA-3; CD141; CD141 antigen; DC141; Fetomodulin; sCD141; soluble CD141; Thrombomodulin; TM
Gene Aliases: AHUS6; BDCA3; CD141; THBD; THPH12; THRM; TM
UniProt ID: (Human) P07204
Entrez Gene ID: (Human) 7056
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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