Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
The Thrombospondin proteins (TSP 1-5) compose a family of glycoproteins that are involved in cell-to-cell and cell-to-matrix signaling. These extracellular, cell-surface proteins form complexes of both homo- and hetero-multimers. Thrombospondins play a role in development, aggregation of platelets, adhesion and migration of cells and progression of cells through the growth cycle. Thrombospondin 1 is released from platelets in response to Thrombin stimulation and is a transient component of the extracellular matrix of developing and repairing tissues. Thrombospondin 2 shares a high degree of homology with Thrombospondin 1, and is thought to have overlapping but unique functions. Thrombospondin 3 is a developmentally regulated heparin-binding protein. Thrombospondin 4 is neuronally expressed and stimulates neurite outgrowth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Thrombospondin-2; Thrombospondin2; TSP2thrombospondin-2
Gene Aliases: Thbs-2; THBS2; TSP-2; TSP2
UniProt ID: (Human) P35442, (Mouse) Q03350
Entrez Gene ID: (Human) 7058, (Mouse) 21826, (Rat) 292406
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support