Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
FIGURE: 1 / 1
Immunogen Sequence: GHQDKDTTFD LFSISNINRK TIGAKQFRGP DPGVPAYRFV RFDYIPPVNA DDLSKITKIM RQKEGFFLTA QLKQDGKSRG TLLALEGPGL SQRQFEIVSN GPADTLDLTY WIDGTRHVVS LEDVGLADSQ WKNVTVQVAG ETYSLHVGCD LIDSFALDEP FYEHLQAEKS RMYVAKGSAR ESHFRGLLQN VHLVFENSVE DILSKKGCQQ GQGAEINAIS ENTETLRLGP HVTTEYVGPS SERRPEVCER SCEELGNMVQ ELSGLHVLVN
The Thrombospondin proteins (TSP 1-5) compose a family of glycoproteins that are involved in cell-to-cell and cell-to-matrix signaling. These extracellular, cell-surface proteins form complexes of both homo- and hetero-multimers. Thrombospondins play a role in development, aggregation of platelets, adhesion and migration of cells and progression of cells through the growth cycle. Thrombospondin 1 is released from platelets in response to Thrombin stimulation and is a transient component of the extracellular matrix of developing and repairing tissues. Thrombospondin 2 shares a high degree of homology with Thrombospondin 1, and is thought to have overlapping but unique functions. Thrombospondin 3 is a developmentally regulated heparin-binding protein. Thrombospondin 4 is neuronally expressed and stimulates neurite outgrowth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Thrombospondin-2; Thrombospondin2; TSP2thrombospondin-2
Gene Aliases: THBS2; TSP2
UniProt ID: (Human) P35442
Entrez Gene ID: (Human) 7058
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