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Trypsin Antibody (PA5-106876) in ICC/IF
Immunofluorescent analysis of Trypsin in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and Trypsin polyclonal antibody (Product # PA5-106876) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-106876
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PRSS1(Accession P07477), corresponding to amino acid residues V71-A121.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2854540
Product Specific Information
Antibody detects endogenous levels of total PRSS1.
Target Information
Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screene for and diagnose Cystic Fibrosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Anionic trypsin I; Anionic trypsin-1; Anionic trypsin-I; Beta-trypsin; Cationic trypsinogen; digestive zymogen; MGC120175; MGC149362; nonfunctional trypsin 1; pancreatic trypsin 1; Pretrypsinogen I; Protease Serine 1; protease, serine, 1; protease, serine, 1 (trypsin 1); protease, serine, 2; Serine protease 1; TCR V beta 4.1; TRYP8; trypsin 1; Trypsin I; Trypsin-1; trypsinogen; trypsinogen 1; trypsinogen 16; trypsinogen A
Gene Aliases: PRSS1; PTRYI; RATPTRYI; TRP1; Try-1; TRY1; TRY4; Trygn16; TRYP1
UniProt ID: (Human) P07477, (Rat) P00762
Entrez Gene ID: (Human) 5644, (Rat) 24691, (Mouse) 114228
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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