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MA1-10617 detects Trypsin from human samples.
MA1-10617 has been successfully used in ELISA applications.
The MA1-10617 immunogen is purified human pancreatic Trypsin.
Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is located in the gastrointestinal tract where it degrades proteins to large peptides. Trypsin prefers lysine and arginine residues. One of the substrates for trypsin is chymotrypsinogen which is cleaved to produce active chymotrypsin. High levels of immunoreactive trypsin in the bloodstream can indicate pancreatic malfunction and this indicator is used to screene for and diagnose Cystic Fibrosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Anionic trypsin I; Anionic trypsin-I; Beta-trypsin; Cationic trypsinogen; digestive zymogen; MGC120175; MGC149362; nonfunctional trypsin 1; Pretrypsinogen I; Protease Serine 1; Serine protease 1; TCR V beta 4.1; TRYP8; Trypsin I; Trypsin-1; trypsinogen; trypsinogen 1; trypsinogen A
Gene Aliases: PRSS1; TRP1; TRY1; TRY4; TRYP1
UniProt ID: (Human) P07477
Entrez Gene ID: (Human) 5644
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