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Product Details
H00007335-B02P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
UBE2V1 (NP_071887.1, 1 a.a. approximately 103 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKEDLNLENF TAKTIYENRI YSLKIECGPK YPEAPPFVRF VTKINMNGVN SSNGVVDPRA ISVLAKWQNS YSIKVVLQEL RRLMMSKENM KLPQPPEGQC YSN
Target Information
The TMEM189-UEV mRNA is an infrequent but naturally occurring co-transcribed product of the neighboring TMEM189 and UBE2V1 genes. Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein produced by this transcript has UEV1 B domains but the protein is localized to the cytoplasm rather than to the nucleus. The significance of this co-transcribed mRNA and the function of its protein product has not yet been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CROC-1; CROC-1UBE2V; CROC1B; DJ1185N5.1.3; DNA-binding protein; KUA-UEV; TRAF6-regulated IKK activator 1 beta Uev1A; ubiquitin conjugating enzyme E2 variant 1; Ubiquitin-conjugating enzyme E2 variant 1; UEV-1; UEV-1CIR1
Gene Aliases: CIR1; CROC-1; CROC1; P/OKcl.19; UBE2V; UBE2V1; UEV-1; UEV1; UEV1A
UniProt ID: (Human) Q13404
Entrez Gene ID: (Human) 7335
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
regulation of DNA repair
postreplication repair
regulation of transcription, DNA-templated
cell differentiation
Fc-epsilon receptor signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of transcription, DNA-templated
T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
nucleotide-binding oligomerization domain containing signaling pathway
protein K63-linked ubiquitination
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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