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Product Details
PA5-65729
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human UBE2V1. Recombinant protein control fragment (Product #RP-104949).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2663244
Product Specific Information
Immunogen sequence: LLEELEEGQKG VGDGTVSWGL EDDEDMTLTR WTGMIIGPPR
Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.
Target Information
The TMEM189-UEV mRNA is an infrequent but naturally occurring co-transcribed product of the neighboring TMEM189 and UBE2V1 genes. Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein produced by this transcript has UEV1 B domains but the protein is localized to the cytoplasm rather than to the nucleus. The significance of this co-transcribed mRNA and the function of its protein product has not yet been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CROC-1; CROC-1UBE2V; CROC1B; DJ1185N5.1.3; DNA-binding protein; KUA-UEV; TRAF6-regulated IKK activator 1 beta Uev1A; ubiquitin conjugating enzyme E2 variant 1; Ubiquitin-conjugating enzyme E2 variant 1; UEV-1; UEV-1CIR1
Gene Aliases: CIR1; CROC-1; CROC1; P/OKcl.19; UBE2V; UBE2V1; UEV-1; UEV1; UEV1A
UniProt ID: (Human) Q13404
Entrez Gene ID: (Human) 7335
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
regulation of DNA repair
postreplication repair
regulation of transcription, DNA-templated
cell differentiation
Fc-epsilon receptor signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of transcription, DNA-templated
T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
nucleotide-binding oligomerization domain containing signaling pathway
protein K63-linked ubiquitination
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