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Product Details
PA5-50696
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human upstream binding protein 1
Conjugate
Form
Liquid
Concentration
2.7 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2636148
Product Specific Information
The antibody detects endogenous levels of total UBP1 protein.
Target Information
UBP1 functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NF2d9; Nuclear factor 2d9; Transcription factor LBP-1; Upstream-binding protein 1
Gene Aliases: Cp2b; LBP-1a; LBP-1B; LBP1; LBP1A; LBP1B; NF2d9; UBP1
UniProt ID: (Human) Q9NZI7, (Mouse) Q811S7
Entrez Gene ID: (Human) 7342, (Mouse) 22221
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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