Product References
Brief Communication: Histological Assessment of Nonhuman Primate Brown Adipose Tissue Highlights the Importance of Sympathetic Innervation.
Journal of obesity
Williams AG,Long M,Kavanagh K
PA1-24894 was used in Immunohistochemistry to support the development of safe sympathetic nervous system stimulants to activate brown adipose tissue for obesity treatment.
Thu Feb 02 00:00:00 EST 2023
Brief Communication: Histological Assessment of Nonhuman Primate Brown Adipose Tissue Highlights the Importance of Sympathetic Innervation.
Journal of obesity
Williams AG,Long M,Kavanagh K
PA1-24894 was used in Immunohistochemistry to support the development of safe sympathetic nervous system stimulants to activate brown adipose tissue for obesity treatment.
Thu Feb 02 00:00:00 EST 2023
Brief Communication: Histological Assessment of Nonhuman Primate Brown Adipose Tissue Highlights the Importance of Sympathetic Innervation.
Journal of obesity
Williams AG,Long M,Kavanagh K
PA1-24894 was used in Immunohistochemistry to support the development of safe sympathetic nervous system stimulants to activate brown adipose tissue for obesity treatment.
Thu Feb 02 00:00:00 EST 2023
Brief Communication: Histological Assessment of Nonhuman Primate Brown Adipose Tissue Highlights the Importance of Sympathetic Innervation.
Journal of obesity
Williams AG,Long M,Kavanagh K
PA1-24894 was used in Immunohistochemistry to support the development of safe sympathetic nervous system stimulants to activate brown adipose tissue for obesity treatment.
Thu Feb 02 00:00:00 EST 2023
Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice.
Nature communications
Efthymiou V,Ding L,Balaz M,Sun W,Balazova L,Straub LG,Dong H,Simon E,Ghosh A,Perdikari A,Keller S,Ghoshdastider U,Horvath C,Moser C,Hamilton B,Neubauer H,Wolfrum C
PA1-24894 was used in Western Blotting to propose AXL receptor as a target for the treatment of obesity.
Thu Jul 13 00:00:00 EDT 2023
Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice.
Nature communications
Efthymiou V,Ding L,Balaz M,Sun W,Balazova L,Straub LG,Dong H,Simon E,Ghosh A,Perdikari A,Keller S,Ghoshdastider U,Horvath C,Moser C,Hamilton B,Neubauer H,Wolfrum C
PA1-24894 was used in Western Blotting to propose AXL receptor as a target for the treatment of obesity.
Thu Jul 13 00:00:00 EDT 2023
A Proteomic Screen to Unravel the Molecular Pathways Associated with Warfarin-Induced or TNAP-Inhibited Arterial Calcification in Rats.
International journal of molecular sciences
Opdebeeck B,Neven E,Maudsley S,Leysen H,Walter D,Geryl H,D'Haese PC,Verhulst A
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Western Blot
Sat Feb 11 00:00:00 EST 2023
A Proteomic Screen to Unravel the Molecular Pathways Associated with Warfarin-Induced or TNAP-Inhibited Arterial Calcification in Rats.
International journal of molecular sciences
Opdebeeck B,Neven E,Maudsley S,Leysen H,Walter D,Geryl H,D'Haese PC,Verhulst A
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Western Blot
Sat Feb 11 00:00:00 EST 2023
Xenon-enhanced computed tomography assessment of brown adipose tissue distribution and perfusion in lean, obese, and diabetic primates.
Obesity (Silver Spring, Md.)
Garside JC,Kavanagh K,Block MR,Williams AG,Branca RT
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Immunohistochemistry
Thu Sep 01 00:00:00 EDT 2022
The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation.
Molecular metabolism
Song Z,Xiaoli AM,Li Y,Siqin G,Wu T,Strich R,Pessin JE,Yang F
PA1-24894 was used in Immunohistochemistry to indicate an important role of CCNC-Mediator in the regulation of BAT development and lipid accumulation in brown adipocytes.
Sat Oct 01 00:00:00 EDT 2022
COVID-19 instigates adipose browning and atrophy through VEGF in small mammals.
Nature metabolism
Jing X,Wu J,Dong C,Gao J,Seki T,Kim C,Urgard E,Hosaka K,Yang Y,Long S,Huang P,Zheng J,Szekely L,Zhang Y,Tao W,Coquet J,Ge M,Chen Y,Adner M,Cao Y
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Immunohistochemistry
Thu Dec 01 00:00:00 EST 2022
COVID-19 instigates adipose browning and atrophy through VEGF in small mammals.
Nature metabolism
Jing X,Wu J,Dong C,Gao J,Seki T,Kim C,Urgard E,Hosaka K,Yang Y,Long S,Huang P,Zheng J,Szekely L,Zhang Y,Tao W,Coquet J,Ge M,Chen Y,Adner M,Cao Y
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Immunohistochemistry
Thu Dec 01 00:00:00 EST 2022
COVID-19 instigates adipose browning and atrophy through VEGF in small mammals.
Nature metabolism
Jing X,Wu J,Dong C,Gao J,Seki T,Kim C,Urgard E,Hosaka K,Yang Y,Long S,Huang P,Zheng J,Szekely L,Zhang Y,Tao W,Coquet J,Ge M,Chen Y,Adner M,Cao Y
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Immunohistochemistry
Thu Dec 01 00:00:00 EST 2022
The Ubiquitin-Specific Peptidase USP18 Promotes Lipolysis, Fatty Acid Oxidation, and Lung Cancer Growth.
Molecular cancer research : MCR
Liu X,Lu Y,Chen Z,Liu X,Hu W,Zheng L,Chen Y,Kurie JM,Shi M,Mustachio LM,Adresson T,Fox S,Roszik J,Kawakami M,Freemantle SJ,Dmitrovsky E
PA1-24894 was used in Immunoprecipitation, Western Blot to reveal that USP18 is a pharmacologic target that controls fatty acid metabolism.
Thu Apr 01 00:00:00 EDT 2021
The Ubiquitin-Specific Peptidase USP18 Promotes Lipolysis, Fatty Acid Oxidation, and Lung Cancer Growth.
Molecular cancer research : MCR
Liu X,Lu Y,Chen Z,Liu X,Hu W,Zheng L,Chen Y,Kurie JM,Shi M,Mustachio LM,Adresson T,Fox S,Roszik J,Kawakami M,Freemantle SJ,Dmitrovsky E
PA1-24894 was used in Immunoprecipitation, Western Blot to reveal that USP18 is a pharmacologic target that controls fatty acid metabolism.
Thu Apr 01 00:00:00 EDT 2021
Oncostatin M suppresses browning of white adipocytes via gp130-STAT3 signaling.
Molecular metabolism
van Krieken PP,Odermatt TS,Borsigova M,Blüher M,Wueest S,Konrad D
PA1-24894 was used in Western Blot to support the notion that OSM negatively regulates thermogenesis in WAT and thus may be an attractive target for treating obesity.
Wed Dec 01 00:00:00 EST 2021
Oncostatin M suppresses browning of white adipocytes via gp130-STAT3 signaling.
Molecular metabolism
van Krieken PP,Odermatt TS,Borsigova M,Blüher M,Wueest S,Konrad D
PA1-24894 was used in Western Blot to support the notion that OSM negatively regulates thermogenesis in WAT and thus may be an attractive target for treating obesity.
Wed Dec 01 00:00:00 EST 2021
Oncostatin M suppresses browning of white adipocytes via gp130-STAT3 signaling.
Molecular metabolism
van Krieken PP,Odermatt TS,Borsigova M,Blüher M,Wueest S,Konrad D
PA1-24894 was used in Western Blot to support the notion that OSM negatively regulates thermogenesis in WAT and thus may be an attractive target for treating obesity.
Wed Dec 01 00:00:00 EST 2021
Adipose gene expression profiles reveal insights into the adaptation of northern Eurasian semi-domestic reindeer (Rangifer tarandus).
Communications biology
Weldenegodguad M,Pokharel K,Niiranen L,Soppela P,Ammosov I,Honkatukia M,Lindeberg H,Peippo J,Reilas T,Mazzullo N,Mäkelä KA,Nyman T,Tervahauta A,Herzig KH,Stammler F,Kantanen J
PA1-24894 was used in Immunohistochemistry (Paraffin), Western Blot to show that highly expressed genes in adipose tissues were associated with fat and lipid metabolism and thermal and energy homoeostasis, promoting the adaptation of reindeer to challenging northern Eurasian environments.
Thu Oct 07 00:00:00 EDT 2021
Adipose gene expression profiles reveal insights into the adaptation of northern Eurasian semi-domestic reindeer (Rangifer tarandus).
Communications biology
Weldenegodguad M,Pokharel K,Niiranen L,Soppela P,Ammosov I,Honkatukia M,Lindeberg H,Peippo J,Reilas T,Mazzullo N,Mäkelä KA,Nyman T,Tervahauta A,Herzig KH,Stammler F,Kantanen J
PA1-24894 was used in Immunohistochemistry (Paraffin), Western Blot to show that highly expressed genes in adipose tissues were associated with fat and lipid metabolism and thermal and energy homoeostasis, promoting the adaptation of reindeer to challenging northern Eurasian environments.
Thu Oct 07 00:00:00 EDT 2021
Integrins and extracellular matrix proteins modulate adipocyte thermogenic capacity.
Scientific reports
Gonzalez Porras MA,Stojkova K,Vaicik MK,Pelowe A,Goddi A,Carmona A,Long B,Qutub AA,Gonzalez A,Cohen RN,Brey EM
PA1-24894 was used in Western Blotting to demonstrate that extracellular matrix interactions regulate adipocyte thermogenic capacity and that ITA7 plays a role in beige adipose formation.
Mon Mar 08 00:00:00 EST 2021
Integrins and extracellular matrix proteins modulate adipocyte thermogenic capacity.
Scientific reports
Gonzalez Porras MA,Stojkova K,Vaicik MK,Pelowe A,Goddi A,Carmona A,Long B,Qutub AA,Gonzalez A,Cohen RN,Brey EM
PA1-24894 was used in Western Blotting to demonstrate that extracellular matrix interactions regulate adipocyte thermogenic capacity and that ITA7 plays a role in beige adipose formation.
Mon Mar 08 00:00:00 EST 2021
Sustained mitochondrial biogenesis is essential to maintain caloric restriction-induced beige adipocytes.
Metabolism: clinical and experimental
Mooli RGR,Mukhi D,Watt M,Edmunds L,Xie B,Capooci J,Reslink M,Eze C,Mills A,Stolz DB,Jurczak M,Ramakrishnan SK
PA1-24894 was used in Western Blot to propose that loss of beige adipocytes upon β3-AR agonist withdrawal could be attenuated by CR.
Mon Jun 01 00:00:00 EDT 2020
Dietary alpha-ketoglutarate promotes beige adipogenesis and prevents obesity in middle-aged mice.
Aging cell
Tian Q,Zhao J,Yang Q,Wang B,Deavila JM,Zhu MJ,Du M
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Western Blot
Wed Jan 01 00:00:00 EST 2020
Adipocyte-specific gp130 signalling mediates exercise-induced weight reduction.
International journal of obesity (2005)
Odermatt TS,Dedual MA,Borsigova M,Wueest S,Konrad D
PA1-24894 was used in Western Blot to investigate the role of adipocyte-specific IL-6 signalling in exercise-mediated appetite control and, hence, weight reduction in obesity.
Sun Mar 01 00:00:00 EST 2020
Cold Exposure Distinctively Modulates Parathyroid and Thyroid Hormones in Cold-Acclimatized and Non-Acclimatized Humans.
Endocrinology
Kovaničová Z,Kurdiová T,Baláž M,Štefanička P,Varga L,Kulterer OC,Betz MJ,Haug AR,Burger IA,Kiefer FW,Wolfrum C,Ukropcová B,Ukropec J
PA1-24894 was used in Western Blotting to suggest that regulation of PTH and thyroid hormones during cold exposure in humans varies by cold acclimatization level and/or cold stimulus intensity.
Wed Jul 01 00:00:00 EDT 2020
Combined extracts of Moringa oleifera, Murraya koeingii leaves, and Curcuma longa rhizome increases energy expenditure and controls obesity in high-fat diet-fed rats.
Lipids in health and disease
Kundimi S,Kavungala KC,Sinha S,Tayi VNR,Kundurthi NR,Golakoti T,Davis B,Sengupta K
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Western Blot
Fri Aug 28 00:00:00 EDT 2020
Combined extracts of Moringa oleifera, Murraya koeingii leaves, and Curcuma longa rhizome increases energy expenditure and controls obesity in high-fat diet-fed rats.
Lipids in health and disease
Kundimi S,Kavungala KC,Sinha S,Tayi VNR,Kundurthi NR,Golakoti T,Davis B,Sengupta K
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Western Blot
Fri Aug 28 00:00:00 EDT 2020
ASK1 inhibits browning of white adipose tissue in obesity.
Nature communications
Lucchini FC,Wueest S,Challa TD,Item F,Modica S,Borsigova M,Haim Y,Wolfrum C,Rudich A,Konrad D
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Western Blot
Thu Apr 02 00:00:00 EDT 2020
ASK1 inhibits browning of white adipose tissue in obesity.
Nature communications
Lucchini FC,Wueest S,Challa TD,Item F,Modica S,Borsigova M,Haim Y,Wolfrum C,Rudich A,Konrad D
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Western Blot
Thu Apr 02 00:00:00 EDT 2020
ASK1 inhibits browning of white adipose tissue in obesity.
Nature communications
Lucchini FC,Wueest S,Challa TD,Item F,Modica S,Borsigova M,Haim Y,Wolfrum C,Rudich A,Konrad D
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Western Blot
Thu Apr 02 00:00:00 EDT 2020
ASK1 inhibits browning of white adipose tissue in obesity.
Nature communications
Lucchini FC,Wueest S,Challa TD,Item F,Modica S,Borsigova M,Haim Y,Wolfrum C,Rudich A,Konrad D
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Western Blot
Thu Apr 02 00:00:00 EDT 2020
Ghrelin ameliorates tumor-induced adipose tissue atrophy and inflammation via Ghrelin receptor-dependent and -independent pathways.
Oncotarget
Liu H,Luo J,Guillory B,Chen JA,Zang P,Yoeli JK,Hernandez Y,Lee II,Anderson B,Storie M,Tewnion A,Garcia JM
PA1-24894 was used in Immunohistochemistry to characterize the pathways involved in AT atrophy in the Lewis Lung Carcinoma (LLC)-induced cachexia model and those mediating the effects of ghrelin in Ghsr +/+ and Ghsr -/- mice.
Tue Sep 01 00:00:00 EDT 2020
Ghrelin ameliorates tumor-induced adipose tissue atrophy and inflammation via Ghrelin receptor-dependent and -independent pathways.
Oncotarget
Liu H,Luo J,Guillory B,Chen JA,Zang P,Yoeli JK,Hernandez Y,Lee II,Anderson B,Storie M,Tewnion A,Garcia JM
PA1-24894 was used in Immunohistochemistry to characterize the pathways involved in AT atrophy in the Lewis Lung Carcinoma (LLC)-induced cachexia model and those mediating the effects of ghrelin in Ghsr +/+ and Ghsr -/- mice.
Tue Sep 01 00:00:00 EDT 2020
PGRMC2 is an intracellular haem chaperone critical for adipocyte function.
Nature
Galmozzi A,Kok BP,Kim AS,Montenegro-Burke JR,Lee JY,Spreafico R,Mosure S,Albert V,Cintron-Colon R,Godio C,Webb WR,Conti B,Solt LA,Kojetin D,Parker CG,Peluso JJ,Pru JK,Siuzdak G,Cravatt BF,Saez E
PA1-24894 was used in Western Blotting to uncover a role for PGRMC2 in intracellular haem transport, reveal the influence of adipose tissue haem dynamics on physiology and suggest that modulation of PGRMC2 may revert obesity-linked defects in adipocytes.
Sun Dec 01 00:00:00 EST 2019
Activation of Anxiogenic Circuits Instigates Resistance to Diet-Induced Obesity via Increased Energy Expenditure.
Cell metabolism
Xie X,Yang H,An JJ,Houtz J,Tan JW,Xu H,Liao GY,Xu ZX,Xu B
PA1-24894 was used in Western Blotting to reveal that increased activities in anxiogenic circuits can reduce body weight by promoting adaptive thermogenesis and basal metabolism via the sympathetic nervous system and suggest that amygdalar GABAergic neurons are a link between anxiety and metabolic dysfunction.
Tue Apr 02 00:00:00 EDT 2019
Inhibition of Mevalonate Pathway Prevents Adipocyte Browning in Mice and Men by Affecting Protein Prenylation.
Cell metabolism
Balaz M,Becker AS,Balazova L,Straub L,Müller J,Gashi G,Maushart CI,Sun W,Dong H,Moser C,Horvath C,Efthymiou V,Rachamin Y,Modica S,Zellweger C,Bacanovic S,Stefanicka P,Varga L,Ukropcova B,Profant M,Opitz L,Amri EZ,Akula MK,Bergo M,Ukropec J,Falk C,Zamboni N,Betz MJ,Burger IA,Wolfrum C
PA1-24894 was used in Western Blotting to investigate if protein geranylgeranylation plays an important role in the regulation of adipocyte browning, possibly through modulating the activity of small GTPases.
Tue Apr 02 00:00:00 EDT 2019
Mice lacking angiotensin type 2 receptor exhibit a sex-specific attenuation of insulin sensitivity.
Molecular and cellular endocrinology
Quiroga DT,Miquet JG,Gonzalez L,Sotelo AI,Muñoz MC,Geraldes PM,Giani JF,Dominici FP
PA1-24894 was used in Western Blotting to suggest a sexual dimorphism in the control of insulin action and glucose homeostasis by the AT2R and reinforce the notion that pharmacological modulation of the balance between the AT1R and AT2R receptor could be important for treatment of metabolic syndrome and type 2 diabetes.
Sun Dec 01 00:00:00 EST 2019
Rosiglitazone Enhances Browning Adipocytes in Association with MAPK and PI3-K Pathways During the Differentiation of Telomerase-Transformed Mesenchymal Stromal Cells into Adipocytes.
International journal of molecular sciences
Fayyad AM,Khan AA,Abdallah SH,Alomran SS,Bajou K,Khattak MNK
PA1-24894 was used in Western Blotting to study the role of brown adipose tissue in the treatment of obesity and related disorders.
Mon Apr 01 00:00:00 EDT 2019
Clonal derivation of white and brown adipocyte progenitor cell lines from human pluripotent stem cells.
Stem cell research & therapy
West MD,Chang CF,Larocca D,Li J,Jiang J,Sim P,Labat I,Chapman KB,Wong KE,Nicoll J,Van Kanegan MJ,de Grey ADNJ,Nasonkin IO,Stahl A,Sternberg H
PA1-24894 was used in Immunocytochemistry-immunoflourescence to describe an alternative approach involving the identification of clonal self-renewing human embryonic progenitor (hEP) cell lines following partial hPS cell differentiation and selection of scalable clones.
Tue Jan 08 00:00:00 EST 2019
Functional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic Improvements.
Cell metabolism
Fabbiano S,Suárez-Zamorano N,Chevalier C,Lazarević V,Kieser S,Rigo D,Leo S,Veyrat-Durebex C,Gaïa N,Maresca M,Merkler D,Gomez de Agüero M,Macpherson A,Schrenzel J,Trajkovski M
PA1-24894 was used in Immunohistochemistry-immunofluorescence to reveal signals critical for our understanding of the microbiota-fat signaling axis during CR and provide potential new anti-obesity therapeutics.
Tue Dec 04 00:00:00 EST 2018
Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors.
EMBO molecular medicine
Bayindir-Buchhalter I,Wolff G,Lerch S,Sijmonsma T,Schuster M,Gronych J,Billeter AT,Babaei R,Krunic D,Ketscher L,Spielmann N,Hrabe de Angelis M,Ruas JL,Müller-Stich BP,Heikenwalder M,Lichter P,Herzig S,Vegiopoulos A
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Western Blot
Wed Aug 01 00:00:00 EDT 2018
Uncoupling protein 1 expression in adipocytes derived from skeletal muscle fibro/adipogenic progenitors is under genetic and hormonal control.
Journal of cachexia, sarcopenia and muscle
Gorski T,Mathes S,Krützfeldt J
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Immunohistochemistry (Paraffin)
Sun Apr 01 00:00:00 EDT 2018
Uncoupling protein 1 expression in adipocytes derived from skeletal muscle fibro/adipogenic progenitors is under genetic and hormonal control.
Journal of cachexia, sarcopenia and muscle
Gorski T,Mathes S,Krützfeldt J
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Immunohistochemistry (Paraffin)
Sun Apr 01 00:00:00 EDT 2018
Jak-TGFβ cross-talk links transient adipose tissue inflammation to beige adipogenesis.
Science signaling
Babaei R,Schuster M,Meln I,Lerch S,Ghandour RA,Pisani DF,Bayindir-Buchhalter I,Marx J,Wu S,Schoiswohl G,Billeter AT,Krunic D,Mauer J,Lee YH,Granneman JG,Fischer L,Müller-Stich BP,Amri EZ,Kershaw EE,Heikenwälder M,Herzig S,Vegiopoulos A
PA1-24894 was used in Immunocytochemistry-immunoflourescence to show that the Jak family of kinases controlled TGFβ signaling in the adipose tissue microenvironment through Stat3 and thereby adipogenic commitment.
Tue Apr 24 00:00:00 EDT 2018
Jak-TGFβ cross-talk links transient adipose tissue inflammation to beige adipogenesis.
Science signaling
Babaei R,Schuster M,Meln I,Lerch S,Ghandour RA,Pisani DF,Bayindir-Buchhalter I,Marx J,Wu S,Schoiswohl G,Billeter AT,Krunic D,Mauer J,Lee YH,Granneman JG,Fischer L,Müller-Stich BP,Amri EZ,Kershaw EE,Heikenwälder M,Herzig S,Vegiopoulos A
PA1-24894 was used in Immunocytochemistry-immunoflourescence to show that the Jak family of kinases controlled TGFβ signaling in the adipose tissue microenvironment through Stat3 and thereby adipogenic commitment.
Tue Apr 24 00:00:00 EDT 2018
Regulator of Calcineurin 1 helps coordinate whole-body metabolism and thermogenesis.
EMBO reports
Rotter D,Peiris H,Grinsfelder DB,Martin AM,Burchfield J,Parra V,Hull C,Morales CR,Jessup CF,Matusica D,Parks BW,Lusis AJ,Nguyen NUN,Oh M,Iyoke I,Jakkampudi T,McMillan DR,Sadek HA,Watt MJ,Gupta RK,Pritchard MA,Keating DJ,Rothermel BA
PA1-24894 was used in Immunohistochemistry to provide evidence that Regulator of Calcineurin 1 (RCAN1) acts to suppress two distinctly different mechanisms of non-shivering thermogenesis (NST).
Sat Dec 01 00:00:00 EST 2018
Regulator of Calcineurin 1 helps coordinate whole-body metabolism and thermogenesis.
EMBO reports
Rotter D,Peiris H,Grinsfelder DB,Martin AM,Burchfield J,Parra V,Hull C,Morales CR,Jessup CF,Matusica D,Parks BW,Lusis AJ,Nguyen NUN,Oh M,Iyoke I,Jakkampudi T,McMillan DR,Sadek HA,Watt MJ,Gupta RK,Pritchard MA,Keating DJ,Rothermel BA
PA1-24894 was used in Immunohistochemistry to provide evidence that Regulator of Calcineurin 1 (RCAN1) acts to suppress two distinctly different mechanisms of non-shivering thermogenesis (NST).
Sat Dec 01 00:00:00 EST 2018
Regulator of Calcineurin 1 helps coordinate whole-body metabolism and thermogenesis.
EMBO reports
Rotter D,Peiris H,Grinsfelder DB,Martin AM,Burchfield J,Parra V,Hull C,Morales CR,Jessup CF,Matusica D,Parks BW,Lusis AJ,Nguyen NUN,Oh M,Iyoke I,Jakkampudi T,McMillan DR,Sadek HA,Watt MJ,Gupta RK,Pritchard MA,Keating DJ,Rothermel BA
PA1-24894 was used in Immunohistochemistry to provide evidence that Regulator of Calcineurin 1 (RCAN1) acts to suppress two distinctly different mechanisms of non-shivering thermogenesis (NST).
Sat Dec 01 00:00:00 EST 2018
Membrane Trafficking Protein CDP138 Regulates Fat Browning and Insulin Sensitivity through Controlling Catecholamine Release.
Molecular and cellular biology
Zhou QL,Song Y,Huang CH,Huang JY,Gong Z,Liao Z,Sharma AG,Greene L,Deng JZ,Rigor MC,Xie X,Qi S,Ayala JE,Jiang ZY
PA1-24894 was used in Western Blot to report that mice without CDP138 develop obesity under normal chow diet (NCD) or high-fat diet (HFD) conditions.
Sun Apr 15 00:00:00 EDT 2018
Short-term thermoneutral housing alters glucose metabolism and markers of adipose tissue browning in response to a high-fat diet in lean mice.
American journal of physiology. Regulatory, integrative and comparative physiology
Clayton ZS,McCurdy CE
PA1-24894 was used in Western Blotting to compare acute changes in glucose metabolism and the metabolic phenotype in lean mice in response to a control diet or high-fat diet (HFD) housed at standard vivarium (22°C) and thermoneutral (30°C) temperatures.
Mon Oct 01 00:00:00 EDT 2018
Short-term thermoneutral housing alters glucose metabolism and markers of adipose tissue browning in response to a high-fat diet in lean mice.
American journal of physiology. Regulatory, integrative and comparative physiology
Clayton ZS,McCurdy CE
PA1-24894 was used in Western Blotting to compare acute changes in glucose metabolism and the metabolic phenotype in lean mice in response to a control diet or high-fat diet (HFD) housed at standard vivarium (22°C) and thermoneutral (30°C) temperatures.
Mon Oct 01 00:00:00 EDT 2018
Glucagon-like peptide-1 regulates brown adipose tissue thermogenesis via the gut-brain axis in rats.
American journal of physiology. Regulatory, integrative and comparative physiology
Krieger JP,Santos da Conceição EP,Sanchez-Watts G,Arnold M,Pettersen KG,Mohammed M,Modica S,Lossel P,Morrison SF,Madden CJ,Watts AG,Langhans W,Lee SJ
PA1-24894 was used in Immunohistochemistry to determine the effect of vagal afferent neuron glucagon like peptide-1 receptor (VAN GLP-1R) signalling on brown adipose tissue thermogenesis.
Mon Oct 01 00:00:00 EDT 2018
Low temperature decreases bone mass in mice: Implications for humans.
American journal of physical anthropology
Robbins A,Tom CATMB,Cosman MN,Moursi C,Shipp L,Spencer TM,Brash T,Devlin MJ
PA1-24894 was used in Western Blotting to show that chronic exposure to low temperature impairs bone architecture, suggesting climate may contribute to phenotypic variation in humans and other hominins.
Thu Nov 01 00:00:00 EDT 2018
Loss of dorsomedial hypothalamic GLP-1 signaling reduces BAT thermogenesis and increases adiposity.
Molecular metabolism
Lee SJ,Sanchez-Watts G,Krieger JP,Pignalosa A,Norell PN,Cortella A,Pettersen KG,Vrdoljak D,Hayes MR,Kanoski SE,Langhans W,Watts AG
PA1-24894 was used in Western Blotting to show that DMH GLP-1R signaling plays a key role for BAT thermogenesis and adiposity.
Tue May 01 00:00:00 EDT 2018
Chronic administration of the angiotensin type 2 receptor agonist C21 improves insulin sensitivity in C57BL/6 mice.
Physiological reports
Quiroga DT,Muñoz MC,Gil C,Pffeifer M,Toblli JE,Steckelings UM,Giani JF,Dominici FP
PA1-24894 was used in Western Blotting to determine the role of angiotensin type 2 receptor.
Wed Aug 01 00:00:00 EDT 2018
Chronic administration of the angiotensin type 2 receptor agonist C21 improves insulin sensitivity in C57BL/6 mice.
Physiological reports
Quiroga DT,Muñoz MC,Gil C,Pffeifer M,Toblli JE,Steckelings UM,Giani JF,Dominici FP
PA1-24894 was used in Western Blotting to determine the role of angiotensin type 2 receptor.
Wed Aug 01 00:00:00 EDT 2018
Angiotensin type 2 receptor activation promotes browning of white adipose tissue and brown adipogenesis.
Signal transduction and targeted therapy
Than A,Xu S,Li R,Leow MK,Sun L,Chen P
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Western Blot
Tue Feb 02 00:00:00 EST 2021
Resveratrol supplementation of high-fat diet-fed pregnant mice promotes brown and beige adipocyte development and prevents obesity in male offspring.
The Journal of physiology
Zou T,Chen D,Yang Q,Wang B,Zhu MJ,Nathanielsz PW,Du M
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Western Blot
Wed Mar 01 00:00:00 EST 2017
Resveratrol supplementation of high-fat diet-fed pregnant mice promotes brown and beige adipocyte development and prevents obesity in male offspring.
The Journal of physiology
Zou T,Chen D,Yang Q,Wang B,Zhu MJ,Nathanielsz PW,Du M
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Western Blot
Wed Mar 01 00:00:00 EST 2017
Maternal Retinoids Increase PDGFRα+ Progenitor Population and Beige Adipogenesis in Progeny by Stimulating Vascular Development.
EBioMedicine
Wang B,Fu X,Liang X,Wang Z,Yang Q,Zou T,Nie W,Zhao J,Gao P,Zhu MJ,de Avila JM,Maricelli J,Rodgers BD,Du M
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Immunohistochemistry
Sat Apr 01 00:00:00 EDT 2017
Alcohol intake aggravates adipose browning and muscle atrophy in cancer-associated cachexia.
Oncotarget
Wang B,Zhang F,Zhang H,Wang Z,Ma YN,Zhu MJ,Du M
PA1-24894 was used in Western Blotting to identify that elevated adipose browning and muscle atrophy through aggravated cancer-associated cachexia is observed during alcohol intake.
Tue Nov 21 00:00:00 EST 2017
Alcohol intake aggravates adipose browning and muscle atrophy in cancer-associated cachexia.
Oncotarget
Wang B,Zhang F,Zhang H,Wang Z,Ma YN,Zhu MJ,Du M
PA1-24894 was used in Western Blotting to identify that elevated adipose browning and muscle atrophy through aggravated cancer-associated cachexia is observed during alcohol intake.
Tue Nov 21 00:00:00 EST 2017
Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein α.
The Journal of biological chemistry
Song Z,Xiaoli AM,Zhang Q,Zhang Y,Yang EST,Wang S,Chang R,Zhang ZD,Yang G,Strich R,Pessin JE,Yang F
PA1-24894 was used in Western Blotting to determine the role of cyclin C in the regulation of brown adipocyte formation.
Fri May 26 00:00:00 EDT 2017
Retinoic acid induces white adipose tissue browning by increasing adipose vascularity and inducing beige adipogenesis of PDGFRα+ adipose progenitors.
Cell discovery
Wang B,Fu X,Liang X,Deavila JM,Wang Z,Zhao L,Tian Q,Zhao J,Gomez NA,Trombetta SC,Zhu MJ,Du M
PA1-24894 was used in Immunohistochemistry to show that retinoic acid induces white adipose tissue browning via activating vascular endothelial growth factor signalling.
Thu Oct 01 00:00:00 EDT 2020
Proteomic Analysis of Human Brown Adipose Tissue Reveals Utilization of Coupled and Uncoupled Energy Expenditure Pathways.
Scientific reports
Müller S,Balaz M,Stefanicka P,Varga L,Amri EZ,Ukropec J,Wollscheid B,Wolfrum C
PA1-24894 was used in western blot to determine use of coupled and uncoupled energy expenditure pathways by proteomic analysis of human brown adipose tissue
Fri Jul 15 00:00:00 EDT 2016
The Gq signalling pathway inhibits brown and beige adipose tissue.
Nature communications
Klepac K,Kilić A,Gnad T,Brown LM,Herrmann B,Wilderman A,Balkow A,Glöde A,Simon K,Lidell ME,Betz MJ,Enerbäck S,Wess J,Freichel M,Blüher M,König G,Kostenis E,Insel PA,Pfeifer A
PA1-24894 was used in western blot to research how beige and brown adipose tissue are inhibited in the Gq signalling pathway
Wed Mar 09 00:00:00 EST 2016
Microbiota depletion promotes browning of white adipose tissue and reduces obesity.
Nature medicine
Suárez-Zamorano N,Fabbiano S,Chevalier C,Stojanović O,Colin DJ,Stevanović A,Veyrat-Durebex C,Tarallo V,Rigo D,Germain S,Ilievska M,Montet X,Seimbille Y,Hapfelmeier S,Trajkovski M
PA1-24894 was used in immunohistochemistry - paraffin section to elucidate how the microbiota-fat signaling axis affects beige-fat development
Tue Dec 01 00:00:00 EST 2015
Activation of natriuretic peptides and the sympathetic nervous system following Roux-en-Y gastric bypass is associated with gonadal adipose tissues browning.
Molecular metabolism
Neinast MD,Frank AP,Zechner JF,Li Q,Vishvanath L,Palmer BF,Aguirre V,Gupta RK,Clegg DJ
Published figure using UCP1 polyclonal antibody (Product # PA1-24894) in Immunohistochemistry
Fri May 01 00:00:00 EDT 2015
Apelin Enhances Brown Adipogenesis and Browning of White Adipocytes.
The Journal of biological chemistry
Than A,He HL,Chua SH,Xu D,Sun L,Leow MK,Chen P
PA1-24894 was used in western blot to investigate apelin signaling in brown adipocyte tissue
Fri Jun 05 00:00:00 EDT 2015
MiR-27 orchestrates the transcriptional regulation of brown adipogenesis.
Metabolism: clinical and experimental
Sun L,Trajkovski M
PA1-24894 was used in immunocytochemistry and western blot to study the central transcriptional role of miRNA-27 in brown adipose tissue adipogenesis following cold exposure
Sat Feb 01 00:00:00 EST 2014
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.jpg?time=20220826?time=20220826 "UCP1 Antibody (PA1-24894) in IHC (P)")
