Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 5
UCP2 Antibody (MA5-31946) in ICC/IF
Immunocytochemistry analysis of UCP2 in Hela cells (green). Sample was incubated with UCP2 monoclonal antibody (Product # MA5-31946) using a dilution of 1:200-1:1000 followed by DRAQ5 fluorescent DNA dye (blue), and Alexa Fluor- 555 phalloidin (red labeled actin filaments) .
Product Details
MA5-31946
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
3F1B9
Immunogen
Purified recombinant fragment of human UCP2 (AA: 1-309) expressed in E. coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2787569
Product Specific Information
MA5-31946 has been tested in indirect ELISA.
Target Information
UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. UCP2 gene is expressed in many tissues, with the greatest expression in skeletal muscle. UCP2 is thought to play a role in non shivering thermogenesis, obesity and diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Dicarboxylate carrier SLC25A8; Mitochondrial uncoupling protein 2; Solute carrier family 25 member 8; UCP 2; UCPH; uncoupling protein; uncoupling protein 2 (mitochondrial, proton carrier)
Gene Aliases: BMIQ4; SLC25A8; UCP2; UCPH
UniProt ID: (Human) P55851
Entrez Gene ID: (Human) 7351
response to superoxide
response to hypoxia
translation
transport
mitochondrial transport
female pregnancy
aging
positive regulation of cell death
proton transport
cellular response to insulin stimulus
cellular response to amino acid starvation
negative regulation of apoptotic process
regulation of mitochondrial membrane potential
negative regulation of insulin secretion involved in cellular response to glucose stimulus
response to fatty acid
cellular response to glucose stimulus
liver regeneration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support